A5072512851- Diabetes Treatment and Management
- Metabolism, Diabetes, and Cancer
- Chronic Disease Management Strategies
- Cancer Genomics and Diagnostics
- Epigenetics and DNA Methylation
- Diabetes Management and Research
- Nutrition and Health in Aging
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Health and Mental Health
- Health Systems, Economic Evaluations, Quality of Life
- Hip and Femur Fractures
- Tracheal and airway disorders
- Drug-Induced Hepatotoxicity and Protection
- Pharmacovigilance and Adverse Drug Reactions
- Laser Applications in Dentistry and Medicine
- Flavonoids in Medical Research
- Workplace Health and Well-being
- Vitamin K Research Studies
- Poisoning and overdose treatments
- Electrolyte and hormonal disorders
- Plant-based Medicinal Research
- Dysphagia Assessment and Management
- Healthcare Systems and Reforms
- Diabetes Management and Education
- Ocular Disorders and Treatments
Fudan University
2004-2024
Xuzhou Medical College
2023-2024
Chengde Medical University
2024
Zhongshan Hospital
2004-2023
Shaanxi University of Chinese Medicine
2023
Second Affiliated Hospital of Nanchang University
2013
Anhui Provincial Center for Disease Control and Prevention
2006
Objective: We aimed to evaluate alirocumab- and evolocumab-related adverse events (AEs) in real-world compared with all other drugs, overall by gender age subgroups; we also compare their risks of cognitive impairment, musculoskeletal disorders diabetes various statins ezetimibe. Methods: retrospectively extracted AE reports from the FDA Adverse Event Reporting System (FAERS) database during July 2015-June 2021. Disproportionality analyses were performed using reporting odds ratios (RORs)...
Abstract Background Individuals with diabetes have increased risk of depression, but there are limited nationally representative studies on this topic. We aimed to investigate the prevalence and predictors as well its impact all-cause cardiovascular mortality in adults type 2 (T2DM) using a prospective cohort study sample U.S. population. Methods analyzed National Health Nutrition Examination Survey (NHANES) data from 2005 2018 linked it most recent publicly available Death Index (NDI) data....
330 Background: Gastrointestinal (GI) cancers totally account for more than one third of the cancerous deaths, yet there is no cost-effective blood-based assay early detection GI cancers. We sought to develop GutSeer, a noninvasive test based on cell-free DNA (cfDNA) methylation and fragmentation signatures derived from single targeted sequencing panel, localization five major cancers, including colorectal (CC), gastric (GC), liver (LC), esophageal (EC), pancreatic cancer (PC). Methods: A...
Introduction: Oral semaglutide is a glucagon-like peptide-1 receptor agonist (GLP-1 RA) that improves glycated hemoglobin levels and body weight in patients with type 2 diabetes (T2DM). We aim to evaluate the cost-effectiveness of once-daily oral comparison placebo injectable GLP-1 RAs Chinese T2DM inadequately controlled on basal insulin. Methods: The United Kingdom Prospective Diabetes Study Outcomes Model (UKPDS OM2.1) was used estimate by calculating incremental ratio (ICER). Baseline...
Gastric aspiration is applied in oral and maxillofacial procedures to reduce postoperative vomiting (POV), yet its clinical benefit remains largely uncertain. Our study aimed determine the role of gastric amelioration POV by a meta-analysis.
The emergence of drug-resistant tuberculosis has necessitated novel treatments like the pretomanid, bedaquiline and linezolid (BPaL) regimen. This study investigated association drug-induced liver injury (DILI) with BPaL regimen compared to first-line antituberculosis drugs (isoniazid, rifampin, pyrazinamide ethambutol [HRZE]).
(1) Objective: To assess the reliability and validity of simplified Chinese version brief Diabetes Quality Life (DQoL) questionnaire in measuring health-related quality life (HRQoL) type 2 diabetes (T2D) patients. (2) Methods: A cross-sectional validation study including 277 patients was conducted at a tertiary hospital Shanghai, China during April–May, 2018. The English DQoL forward back-translated into Chinese. expert interview, exploratory factor analysis (EFA), Spearman correlation with...
Background: Evidence is lacking on risk factors for frailty and prefrailty their relationship with self-management behaviors in patients ≥40 years of age type 2 diabetes. Methods: Participants were selected as a cross-sectional cohort at five communities Shanghai, China during January–March 2021. The modified FRAIL scale the Summary Diabetes Self-Care Activities (SDSCA) measure used. Results: Of 558 participants, 10.2% classified 34.1% prefrailty. prevalence was higher males than females (p...
Objectives To describe the development of pharmaceutical retail market and community pharmacists in mainland China identify challenges from both government business perspectives. Design A retrospective cross-sectional study. Setting Community pharmacies providing primary care China. Participants all 31 provincial units registered National Medical Products Administration during 2014–2020. Number ranged 433 529 (2014) to 553 892 (2020). 129 895 541 264 Primary secondary outcome measures...
Rhabdomyolysis is a life-threatening adverse drug reaction that seldom reported in DPP-4 inhibitors. Here we present case which 58-year-old female suffered from severe swelling and pain bilateral lower limbs oliguria for 1 week after suicidal attempt she took vildagliptin 1,400 mg insulin aspart 60 IU. She was diagnosed with rhabdomyolysis, diabetic ketoacidosis (DKA), urinary tract infection (UTI) drug-induced liver injury (DILI). After 20 days of hospitalization, significant improvement...
Abstract Background This research aims to examine the frequency, age-related distribution, and intensity of preoperative hyponatremia among elderly individuals with hip fractures. study provide valuable insights into diagnosis in this patient population. Methods involved analysis clinical data obtained from 419 fractures (referred as fracture group) 166 undergoing routine health examinations (designated control group). A comprehensive comparison was conducted, examining baseline...
Rhabdomyolysis is a life-threatening syndrome associated with direct or indirect muscle damage that rarely reported dipeptidyl peptidase (DPP)-4 inhibitors. Here we presented case in which 58-year-old female suffered from severe swelling and pain bilateral lower limbs oliguria after suicidal vildagliptin overdose. Drug-induced rhabdomyolysis drug-induced liver injury were diagnosed based on laboratory radiological findings. The patient was treated fluid resuscitation, insulin, electrolyte...
Objectives To assess the contemporary prevalence and decadal trends of depression antidepressant use among adults with cardiovascular disease (CVD) in United States, as well their risk factors from 2009 to 2020. Materials methods We used National Health Nutrition Examination Survey data calculate weighted use. Adults aged 20 years or older CVD were included. Depression assessed by Patient Questionnaire (PHQ-9) self-report, respectively. Results A total 3,073 eligible participants >20...
Objective To investigate the effects of catheter balloon dilatation on patients with dysphagia caused by neurogenic cricopharyngeal achalasia.Methods Thirty-two achalasia were divided randomly into a treatment group (n =16) and control =16).The received therapy routine rehabilitation training; was treated training only.Both groups tested before treatment,after 3 weeks (after treatment) at 6 months after (follow-up).All cases evaluated using Saitoh's 7-grade swallowing assessment...
4069 Background: Esophageal and gastric cancer (EC GC) are two common types that severely impact patients’ health. The 5-year survival rate for EC GC is as low 19% 31%, respectively. However, early detection will significantly increase the rate: stage-1 has a of 51%, while it’s 69%. Invasive screening methods, such endoscopy biopsy, caused compliance. Computational tomography carcinoembryonic antigen were limited by sensitivity. To address this problem, we developed GaEsSeer, non-invasive...
4169 Background: Five major gastrointestinal (GI) cancers - colorectal (CRC), gastric (GC), liver (LC), esophageal (EC), and pancreatic cancer (PC) are responsible for hundreds of thousands mortalities annually worldwide. Unfortunately, there is a lack cost-effective, blood-based screening method their early detection. To address this issue, we aimed to develop GutSeer, noninvasive, targeted methylation sequencing-based test by leveraging fragmentomic signatures carried cell-free DNA...
Diabetic diarrhea is one of the chronic complications diabetes mellitus, which belongs to kind gastrointestinal autonomic neuropathy, and can seriously affect quality life patients. In recent years, Traditional Chinese medicine has achieved more satisfactory efficacy in treatment diabetic diarrhea. addition herbal medicine, acupuncture, acupoint plasters other special therapies significantly improve clinical symptoms patients life. This article mainly summarizes order provide new ideas for...
Diabetes peripheral neuropathy (DNP) is a chronic complication of nerve injury caused by long-term onset diabetes. In recent years, with the in-depth study Chinese medicine in diabetes neuropathy, Buyang Huanwu Decoction has made some progress its treatment. This article studies mechanism and clinical efficacy on provides new method for treatment neuropathy.
Objective To explore the therapeutic effect of radioactive 125I seeds combined with chemotherapy on treatment inoperative pancoast tumor by CT-guided percutaneous implantation planning system (TPS). Methods From December 2002 to 2010, 36 patients were confirmed imaging and pathology. Among them, 26 cases suffered from squamous cell carcinoma 10 adenocarcinoma. At 1 week after implantation, was administered as intravenous 000 mg / m2 gemcitabine at 8 d cisplatin 75 for 4 consecutive...