Wiston William
A5057357384- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- HIV Research and Treatment
- HIV/AIDS drug development and treatment
- Virology and Viral Diseases
- vaccines and immunoinformatics approaches
- HIV/AIDS oral health manifestations
- SARS-CoV-2 and COVID-19 Research
- Adolescent Sexual and Reproductive Health
- Digital Imaging for Blood Diseases
National Institute for Medical Research
2022-2023
Objective: To describe challenges posed by COVID-19 on TB commodity supply, care cascade, active case finding, and responses taken healthcare workers (HCWs) community health (CHWs) during the first year of pandemic (March 2020 to February 2021). Design: A qualitative descriptive study involving 25 in-depth interviews 10 focus group discussions conducted in July 2022. Setting: 37 treatment facilities were purposively selected from seven regions due high notifications 2019 their provision...
Abstract Background The Pox-Protein Public-Private Partnership is performing a suite of trials to evaluate the bivalent subtype C envelope protein (TV1.C and 1086.C glycoprotein 120) vaccine in context different adjuvants priming agents for human immunodeficiency virus (HIV) type 1 (HIV-1) prevention. Methods In HIV Vaccine Trials Network 111 trial, we compared safety immunogenicity DNA prime followed by DNA/protein boost with coadministration injected intramuscularly via either...
Abstract Human immunodeficiency virus type 1 (HIV-1)-neutralizing antibodies (nAbs) that prevent infection are the main goal of HIV vaccine discovery. But as no nAb-eliciting vaccines yet available, only data from HIV-1 neutralizers—persons with who naturally develop broad and potent nAbs—can inform about dynamics durability nAb responses in humans, knowledge which is crucial for design future regimens. To address this, we assessed HIV-1-neutralizing immunoglobulin G (IgG) 2,354 persons on...
Background: Rapid diagnostic tests (RDTs) have played a critical role in the detection and monitoring of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections globally. A number RDTs are currently available, their accuracy is dependent on several factors that include disease stage, circulating virus variants at particular time, population being tested. This study aimed to evaluate performance characteristics two RDTs, StandardTM Q IgM/IgG Wantai SARS-CoV-2 Ab Test, for...
PrEP literacy is influenced by many factors including the types of information available and how it interpreted. The level may influence acceptability uptake.We conducted 25 in-depth interviews in a HIV vaccine trial preparedness cohort study. We explored what participants knew about PrEP, sources knowledge much they know PrEP. used framework approach to generate themes for analysis guided Social Ecological Model examined levels using individual interpersonal constructs SEM.We found that...
HIV-care programmes are faced with significant challenges in getting newly diagnosed People Living Human Immunodeficiency Virus (PLHIV) linked to care despite massive investment HIV prevention, treatment and care. This study assessed the performance of mobile Testing Counseling service (mHTC) provision HIV-testing linkage PLHIV from Key Vulnerable Populations (KVPs). A retrospective review records 25,248 clients was extracted mHTC database October-2016 September-2018. Of clients, 51.71% were...