A5080411201- Diphtheria, Corynebacterium, and Tetanus
- Mycobacterium research and diagnosis
- Genomics and Phylogenetic Studies
- Bacterial Genetics and Biotechnology
- Bacteriophages and microbial interactions
- Bioinformatics and Genomic Networks
- Bacterial Identification and Susceptibility Testing
- Microbial Community Ecology and Physiology
- Enzyme-mediated dye degradation
- Gene Regulatory Network Analysis
- Microbial Metabolic Engineering and Bioproduction
- Biofuel production and bioconversion
- RNA and protein synthesis mechanisms
- Genetics, Bioinformatics, and Biomedical Research
- Machine Learning in Bioinformatics
- Microbial Metabolism and Applications
- Gene expression and cancer classification
- Plant biochemistry and biosynthesis
- Microbial Natural Products and Biosynthesis
- Brain Tumor Detection and Classification
- Bacterial biofilms and quorum sensing
- Veterinary medicine and infectious diseases
- Scientific Computing and Data Management
- CRISPR and Genetic Engineering
Universidade Federal de Minas Gerais
2015-2025
Technical University of Munich
2020-2021
Methods based around statistics and linear algebra have been increasingly used in attempts to address emerging questions microarray literature. Microarray technology is a long-used tool the global analysis of gene expression, allowing for simultaneous investigation hundreds or thousands genes sample. It characterized by low sample size large feature number created non-square matrix, incomplete rank, that can generate countless more solution classifiers. To avoid problem 'curse...
The genus Pseudomonas includes metabolically versatile microorganisms occupying diverse niches, from environmental habitats to plant pathogens, and has clinically significant strains. For this reason, spp. might act as a reservoir of antimicrobial resistance genes, which have been detected even in isolated environments. aim study was report the susceptibility profile 25 fluorescens isolates soil samples collected on King George Island (Antarctic Peninsula), select non-clonal with unusual...
Abstract We present the newest version of CoryneRegNet, reference database for corynebacterial regulatory interactions, available at www.exbio.wzw.tum.de/coryneregnet/ . The exponential growth next-generation sequencing data in recent years has allowed a better understanding bacterial molecular mechanisms. Transcriptional regulation is one most important mechanisms adaptation and survival. These may be understood via an organism’s network interactions. Although Corynebacterium genus medical,...
Iron is an essential micronutrient for the growth and development of virtually all living organisms, playing a pivotal role in proliferative capability many bacterial pathogens. The impact that bioavailability iron has on transcriptional response species CMNR group been widely reported some members group, but it hasn't yet as deeply explored Corynebacterium pseudotuberculosis. Here we describe first time comprehensive RNA-seq whole transcriptome analysis T1 wild-type Cp13 mutant strains C....
Trametes villosa is a remarkable white-rot fungus (WRF) with the potential to be applied in lignocellulose conversion obtain chemical compounds and biofuels. Lignocellulose breakdown by WRF carried out through secretion of oxidative hydrolytic enzymes. Despite existing knowledge about this process, complete molecular mechanisms involved regulation metabolic system have not yet been elucidated. Therefore, order understand genes pathways regulated during degradation, strain T. CCMB561 was...
Antarctica is a mosaic of extremes. It harbors active polar volcanoes, such as Deception Island, marine stratovolcano having notable temperature gradients over very short distances, with the reaching up to 100 °C near fumaroles and subzero temperatures being noted in glaciers. From sediments we isolated representatives genus Anoxybacillus, widely spread that mainly encountered thermophilic environments. However, phylogeny this its adaptive mechanisms geothermal sites cold environments remain...
Corynebacterium pseudotuberculosis is a pathogenic bacterium which has been rapidly spreading all over the world, causing economic losses in agricultural sector and sporadically infecting humans. Six C. strains were isolated from goats, sheep, horses with distinct abscess locations. For first time, Mexican genomes of this sequenced studied silico. All using Ion Personal Genome Machine sequencer, assembled Newbler SPAdes software. The automatic genome annotation was done software RAST...
The number of draft genomes deposited in Genbank from the National Center for Biotechnology Information (NCBI) is higher than complete ones. Draft are assemblies that contain fragments misassembled regions (gaps). Such present a hindrance to understanding biology and evolution organism since they lack genomic information. To overcome this problem, strategies improve assembly process developed continuously. Also, greatest challenge progress presence repetitive DNA regions. This article...
In order to develop efficient microbial recycling strategies for rubber waste materials, it is required that we understand the degradation pathway of polymer and how regulated. However, only little known about transcriptional regulation pathway, which seems be upregulated in presence polymer. We identified a novel key regulator (CRP VH2 ) regulates several parts potent rubber-degrader G. polyisoprenivorans VH2. Furthermore, provide evidence widespread involvement CRP regulators various other...
Background: Transcriptional regulation of gene expression is crucial for the adaptation and survival bacteria. Regulatory interactions are commonly modeled as Gene Networks (GRNs) derived from experiments such RNA-seq, microarray ChIP-seq. While reconstruction GRNs fundamental to decipher cellular function, even economically important bacteria Corynebacterium glutamicum incomplete. Materials Methods: Here, we analyzed predictive power if used in silico models investigated consistency C. GRN...
We present here the complete genome sequence of Corynebacterium pseudotuberculosis strain 12C, isolated from a sheep abscess in Brazil. The sequencing was performed with Ion Torrent Personal Genome Machine (PGM) system, fragment library, and coverage ~48-fold. presented is circular chromosome 2,337,451 bp length, 2,119 coding sequences, 12 rRNAs, 49 tRNAs, G+C content 52.83%.
Small RNAs (sRNAs) are one of the key players in post-transcriptional regulation bacterial gene expression. These molecules, together with transcription factors, form regulatory networks and greatly influence landscape. Little is known concerning sRNAs their on machinery genus Corynebacterium , despite its medical, veterinary biotechnological importance. Here, we expand corynebacterial knowledge by integrating interactions into transcriptional six species, covering four human animal...