A5081337273- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- COVID-19 and healthcare impacts
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiac Arrest and Resuscitation
- Cardiovascular and Diving-Related Complications
- Respiratory Support and Mechanisms
- Renal function and acid-base balance
- Sepsis Diagnosis and Treatment
- Cardiac Health and Mental Health
- Climate Change and Health Impacts
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Risk Factors
- Cardiovascular Health and Disease Prevention
- COVID-19 Impact on Reproduction
- Venous Thromboembolism Diagnosis and Management
- Cancer Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations and Hemangiomas
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Phonocardiography and Auscultation Techniques
- Atrial Fibrillation Management and Outcomes
- ECG Monitoring and Analysis
Rush University Medical Center
2017-2023
Cedars-Sinai Smidt Heart Institute
2021-2022
Sharp Memorial Hospital
2022
Cedars-Sinai Medical Center
2021-2022
University of Florida
2022
Thomas Jefferson University Hospital
2021-2022
Rush University
2018-2022
Augusta University
2020
Background: To investigate sex differences in coronavirus disease 2019 (COVID-19) outcomes a large Illinois-based cohort.
COVID-19 has significant case fatality. Glucocorticoids are the only treatment shown to improve survival, but among patients requiring supplemental oxygen. WHO advises seek medical care for "trouble breathing," hypoxemic frequently have no respiratory symptoms. Our cohort study of hospitalized shows that symptoms uncommon and not associated with mortality. By contrast, objective signs compromise-oxygen saturation rate-are markedly elevated findings support expanding guidelines include...
The novel COVID-19 has had an unprecedented and devastating spread internationally. infection can lead to a number of cardiovascular sequelae, including heart failure, which may portend worse clinical outcomes. Here, we report rare case 57-year-old woman who developed acute left ventricular systolic dysfunction with apical ballooning consistent takotsubo cardiomyopathy (TCM), mixed cardiogenic septic shock in the setting disease. We briefly review pathophysiology diagnosis TCM (also...
Background Venous thromboembolism (VTE) contributes significantly to COVID-19 morbidity and mortality. The urokinase receptor system is involved in the regulation of coagulation. Levels soluble plasminogen activator (suPAR) reflect hyperinflammation are strongly predictive outcomes COVID-19. Whether suPAR levels identify patients with at risk for VTE unclear. Methods Results We leveraged a multinational observational study hospitalized D-dimer measured on admission. In 1960 (mean age, 58...
Abstract Background Recent evidence challenges the current standard of offering surgery to patients with ileocecal Crohn’s disease only when they present complications disease. Methods A retrospective, multicenter comparative analysis was performed including operated for primary CD at 12 referral centers. Patients were divided in 2 groups, according indication inflammatory (ICD) or complicated (CCD) phenotype. Short-term results compared. on isolated ileocaecal (last 50 cm terminal ileum and...
7533 Background: Patients (p) with low BRCA1 mRNA levels attained longer survival when treated cisplatin-based chemotherapy (Taron et al. 2004), while p high taxanes-based therapy (Quinn 2007). Early NSCLC whose tumors had significantly worse (Rosell Upregulated is part of a characteristic gene signature in aggressive lung cancers (Deeb Methods: Adjuvant was customized based on 84/100 completely resected N1 and N2 p. 11 received docetaxel (doc); 29 intermediate doc/cisplatin (cis); 44...
Focused transthoracic echocardiography (fTTE) has emerged as a critical diagnostic tool during the COVID-19 pandemic, allowing for efficient cardiac imaging while minimizing staff exposure. The utility of fTTE in predicting clinical outcomes remains under investigation.We conducted retrospective study 2,266 hospitalized patients at Rush University Medical Center with infection between March and November 2020 who received fTTE. data were analyzed association primary adverse (60-day mortality)...
To compare the characteristics and outcomes of COVID-19 patients with a hyperdynamic LVEF (HDLVEF) to those normal or reduced LVEF.Retrospective study.Rush University Medical Center.Of 1682 adult hospitalized COVID-19, 419 had transthoracic echocardiogram (TTE) during admission met study inclusion criteria.Participants were divided into (LVEF < 50%), (≥50% <70%), (≥70%) groups.LVEF was assessed as predictor 60-day mortality. Logistic regression used adjust for age BMI.There no difference in...
Patients with pre-existing cardiovascular disease may carry a higher risk for mortality from COVID-19. This study examined the association between individuals admitted COVID-19 and their clinical outcomes.A retrospective cohort was conducted on patients to Rush University System Health (RUSH) identify factors associated increased major adverse events (MACE; composite of death, stroke, myocardial injury, heart failure exacerbation). Multivariable logistic regression used adjust demographic...
Chest computed tomography (chest CT) is routinely obtained to assess disease severity in COVID-19. While pulmonary findings are well-described COVID-19, the implications of cardiovascular less well understood. We evaluated impact on chest CT adverse composite outcome (ACO) hospitalized COVID-19 patients.
Lymphoepithelioma-likethymic carcinoma is a rare neoplasm that presents with compressive symptoms or as an incidental radiological finding of anterior mediastinal mass. It aggressive high rate invasion, metastasis and recurrence. Its diagnosis usually carries poor prognosis largely due to propensity for late diagnosis. To date, guidance treatment remains limited. This case lymphoepithelioma-like thymic in young male adult who presented initially back pain. Despite prompt initiation...
Patent foramen ovale (PFO) is present in about 25% of the population. Platypnea-orthodeoxia syndrome (POS), which dyspnea and hypoxemia upright position that relieved when supine, a rare manifestation PFO. We describe case 74-year-old woman who presented with new-onset hypoxia. A PFO dilated aorta causing POS were found on workup. Symptoms resolved after undergoing percutaneous closure. This highlights mechanism by an ascending aortic aneurysm can alter hemodynamics through existing PFO,...
In the coronavirus disease 2019 (COVID-19) global pandemic, patients with cardiovascular represent a vulnerable population higher risk for contracting COVID-19 and worse prognosis case fatality rates. However, relationship between heart failure (HF) is unclear, specifically whether HF an independent factor severe infection or if other accompanying comorbidities are responsible increased risk.This retrospective analysis of 1331 adult diagnosed March June 2020 admitted at Rush University...
Introduction: The novel coronavirus disease 2019 (COVID-19) pandemic has affected millions of people worldwide. Higher COVID-19 mortality in men compared to women seen many countries is not yet explained. We analyzed sex differences outcomes a large Illinois-based cohort. Methods: This multicenter retrospective cohort study confirmed infections from March 1–June 3, 2020 Rush University System. and with infection for the rates hospitalization, intensive care unit (ICU) admission, vasopressor...
Study the clinical outcomes associated with number of concomitant vasopressors used in critically ill COVID-19 patients.
This study sought to assess the predictive value of H2FPEF score in patients with COVID-19.Retrospective study.Rush University Medical Center.A total 1682 had an echocardiogram year preceding their COVID-19 admission a preserved ejection fraction (≥50%). A 156 met inclusion criteria.Patients were divided into low (0-2), intermediate (3-5), and high (6-9) groups outcomes compared.Adjusted multivariable logistic regression models evaluated association between group composite outcome for severe...
Abstract Introduction Preventing hospital readmissions can improve a patient's quality of life and decrease healthcare costs. While prior work has focused on pre-existing comorbidities to predict COVID-19 readmissions, the prognostic role in-hospital data complications been less studied. Methods Data was collected adult patients diagnosed with admitted multicenter system in Illinois between March November 2020. Our cohort consisted hospitalization survivors excluding those discharged hospice...