A5087600444- Dental materials and restorations
- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- Laser Applications in Dentistry and Medicine
- Photopolymerization techniques and applications
- Dental Radiography and Imaging
- Dental Erosion and Treatment
- Additive Manufacturing and 3D Printing Technologies
- Periodontal Regeneration and Treatments
- Endodontics and Root Canal Treatments
- Electrospun Nanofibers in Biomedical Applications
- Photodynamic Therapy Research Studies
- Advanced Drug Delivery Systems
- Advanced materials and composites
- Mesenchymal stem cell research
- Aerogels and thermal insulation
- Oral microbiology and periodontitis research
- 3D Printing in Biomedical Research
- Hydrogels: synthesis, properties, applications
- Dental Anxiety and Anesthesia Techniques
- biodegradable polymer synthesis and properties
- Biopolymer Synthesis and Applications
- Bone and Dental Protein Studies
- Contact Dermatitis and Allergies
- Cerebrovascular and Carotid Artery Diseases
University of Debrecen
2015-2024
Medical University of South Carolina
2024
Baranya Megyei Kórház
2014-2020
Hungarian Academy of Sciences
2012
Institute of Materials and Environmental Chemistry
2007
Red Deer Regional Hospital
2006
University of Münster
2001
University of British Columbia
1988-1989
Vancouver Hospital and Health Sciences Centre
1988
Objectives: Using dental Ti implants has become a well-accepted and used method for replacing missing dentition. It evident that in many cases peri-implant inflammation develops. The objective was to create evaluate the antibacterial effect of silver nanoparticle (Ag-NP) coated surfaces can help prevent such processes if applied on surface implants. Methods: Annealing I, Ag ion implantation by beam an Electron Cyclotron Resonance Ion Source (ECRIS), Physical Vapor Deposition (PVD), II...
Bone morphogenetic protein 2 (BMP-2) is a member of the transforming growth factor-β superfamily, it known to be factor involved in skeletal development and capable inducing vitro osteogenic differentiation mesenchymal stem cells (MSCs). Dental pulp (DPSCs) isolated from extracted third molar teeth are an ideal resource for bone tissue engineering regeneration applications, due their convenient isolation, safe cryopreservation, easy maintenance cell cultures. The aims this study were deliver...
In this study, scaffolds were prepared via an electrospinning method for application in oral cavities. The hydrophilicity of the fiber mesh is paramount importance, as it promotes cell spreading; however, most commonly used polyvinyl alcohol (PVA) and other hydrophilic meshes immediately disintegrate aqueous media. contrast, excessive hydrophobicity already inhibits cells adhesion on surface. Therefore, needed to be optimized. Scaffolds with different (PVA)/chitosan/citric acid ratios...
Electrospinning has recently been recognized as a potential method for use in biomedical applications such nanofiber-based drug delivery or tissue engineering scaffolds. The present study aimed to demonstrate the electrospinning preparation and suitability of β-tricalcium phosphate-modified aerogel containing polyvinyl alcohol/chitosan fibrous meshes (BTCP-AE-FMs) bone regeneration under vitro vivo conditions. mesh physicochemical properties included 147 ± 50 nm structure, aqueous media...
The in situ application of the combination different types drugs revolutionized area periodontal therapy. purpose this study was to develop nanocomposite hydrogel (NCHG) as a pH-sensitive drug delivery system. To achieve local applicability NCHG dental practice, routinely used blue-light photopolymerization chosen for preparation. setting time 60 s, which resulted stable structures. Universal Britton-Robinson buffer solutions were investigate effect pH range 4-12 on release that can be...
Background and Purpose —This study aimed to determine the correlation of in vivo ultrasound measurements intima-media thickening (IMT), lumen diameter, cross-sectional area common carotid artery (CCA) with corresponding obtained by gross pathology histology. Methods —Sixty-six moribund neurological patients (mean age 71 years) underwent B-mode CCA a few days before death. During autopsy, specimens were removed toto. Carotid arteries ligated cannulated for injection hydrophilic embedding...
Poly(ADP-ribose) polymerase-1 (PARP1) is a pro-inflammatory protein, whose properties were demonstrated in human. The of PARP1 shown Th1- and Th2-mediated inflammatory pathologies, but not Th17-mediated inflammation. Thus, we studied the role imiquimod-induced model psoriasis. To our surprise, psoriasis, acted as an anti-inflammatory factor its genetic deletion exacerbated symptoms. We showed that absence PARP1, epidermis thickened number TUNEL-positive cells decreased epidermis. These data...
Gold nanoparticles (AuNPs) display surface plasmon resonance (SPR) as a result of their irradiation at targeted light frequency. SPR also results in heat production that increases the temperature surrounding environment, affecting polymerization. The aim was to investigate effect AuNPs on dimethacrylate-based photopolymer system. tested composites were designed overlap illumination required for polymerization and effect. 5 nm-sized dodecanethiol capped applied different concentrations matrix...
Our knowledge on the bonding mechanisms between metal and ceramic parts of dental systems is very limited. This work tested hypothesis that details interface processes can be described in framework a chemical diffusion model. The development interfacial phases was investigated by cross-sectional analytical transmission electron microscopy NiCr (Wiron 99) alloy three different ceramics (Carat, Vita VMK 95, Vision). All were at normal firing conditions (suggested manufacturer) increased times...
Bone morphogenetic protein-2 (BMP-2), is a potential factor to enhance osseointegration of dental implants. However, the appropriate cellular system investigate osteogenic effect BMP-2 in vitro standardized manner still needs be defined. The aim this study was examine on cell proliferation and differentiation human progenitors various origins: pulp stem cells (DPSC), osteosarcoma line (Saos-2) embryonic palatal mesenchymal (HEPM). For induction differentiation, culture medium supplemented...
In this paper, the synthesis, characterization, and properties of crosslinked poly(ε-caprolactone)-based polyurethanes as potential tissue replacement materials are reported. The polyurethane prepolymers were prepared from poly(ε-caprolactone)diol (PCD), polyethylene glycol (PEG)/polylactic acid diol (PLAD), 1,6-hexamethylene diisocyanate (HDI). these segmented polyurethanes, role PEG/PLAD was to tune hydrophobic/hydrophilic character resulting polymer while sucrose served a crosslinking...
Abstract The inhibitory phosphorylation of endothelial nitric oxide (NO) synthase (eNOS) at Thr497 (eNOS pThr497 ) by protein kinase C or RhoA-activated is a major regulatory determinant eNOS activity. signalling mechanisms involved in the dephosphorylation have not yet been clarified. This study identifies myosin phosphatase (MP) holoenzyme consisting phosphatase-1 catalytic subunit (PP1c) and MP target subunit-1 (MYPT1) as an phosphatase. In support this finding are: (i) MYPT1 interacts...
The surface properties of metallic implants play an important role in their clinical success. Improving upon the inherent shortcomings Ti implants, such as poor bioactivity, is imperative for achieving use. In this study, we have developed a implant modified with Ca or dual + Si ions on using electron cyclotron resonance ion source (ECRIS). physicochemical and biological ion-implanted surfaces were analyzed various analytical techniques, analyses, potentiodynamic polarization cell culture....
BMP-7 has shown inductive potential for in vitro osteogenic differentiation of mesenchymal stem cells, which are an ideal resource regenerative medicine. Externally applied, recombinant was able to induce the DPSCs but based on our previous results with BMP-2, we aimed study effect tetracyclin-inducible expression these cells. DPSC, mock, and DPSC-BMP-7 cell lines were cultured presence or absence doxycycline, then alkaline phosphatase (ALP) activity, mineralization, mRNA levels different...