- Monoclonal and Polyclonal Antibodies Research
- Heme Oxygenase-1 and Carbon Monoxide
- Redox biology and oxidative stress
- Electron Spin Resonance Studies
- Autophagy in Disease and Therapy
- Neuroscience and Neuropharmacology Research
- Magnolia and Illicium research
- Viral Infections and Immunology Research
- Immune cells in cancer
- Sirtuins and Resveratrol in Medicine
- Hemoglobin structure and function
- Neuroinflammation and Neurodegeneration Mechanisms
- Sperm and Testicular Function
- Immune Response and Inflammation
- Crystal structures of chemical compounds
- Coccidia and coccidiosis research
- Paraquat toxicity studies and treatments
- MicroRNA in disease regulation
- Neurological Disorders and Treatments
- Phagocytosis and Immune Regulation
- Influenza Virus Research Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Sulfur Compounds in Biology
- Aquaculture disease management and microbiota
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Chinese Academy of Sciences
2021
Guangzhou Medical University
2021
University of Missouri
2021
Taiyuan Iron and Steel Group (China)
2020
Wuhan Children's Hospital
2018
Huazhong University of Science and Technology
2018
Mudanjiang Medical University
2017
Air Force Medical University
2000-2015
Xijing Hospital
2012-2015
Chinese Academy of Fishery Sciences
2015
Abstract In this study, we characterized the functional role of long noncoding RNA (lncRNA), brain derived neurotrophic factor anti‐sense (BDNF‐AS) in regulating D‐glucose‐induced (DGI) apoptosis human retinal pigment epithelial (RPE) cells. Human RPE cell line, ARPE‐19 cells were cultured vitro and treated with various concentrations D‐glucose for 24 h. A TUNEL assay was applied immunohistochemical quantitative approaches to assess apoptotic effect D‐glucose. Under condition 50 mM...
Abstract Excessive N-methyl-D-aspartate receptor (NMDAR) activation and the resulting of neuronal nitric oxide synthase (nNOS) cause injury. Homer1b/c facilitates NMDAR-PSD95-nNOS complex interactions, Homer1a is a negative competitor Homer1b/c. We report that was both upregulated by protected against NMDA-induced injury in vitro vivo . The neuroprotective activity associated with Ca 2+ influx, oxidative stress resultant downstream signaling activation. Additionally, we found functionally...
To explore the therapeutic effect of honokiol on particulate matter 2.5 (PM2.5)-induced lung injury in asthmatic mice and possible mechanisms. Methods: A total 32 BALB/C were randomly divided into four groups: a normal saline group, model PM2.5 group (n=8 each group). The asthma mouse was established by ovalbumin treatment. treated with physiological saline, ovalbumin, honokiol, respectively. Lung tissues serum collected. pathological changes evaluated. levels inflammatory cytokines...
The hepatitis A virus specific immunoglobulin M (IgM) antibody is a serological marker for early diagnosis of A. At present, the methods used at home or abroad detecting anti-HAV IgM are RIA, ELISA and SPHAI. dot immunogold combination assay that has been developed since 1989 new technique with property simple rapid immunological detection, by using red colloidal gold particles to label antibodies as indicator, millipore filtering membrane coated antigen carrier. Affected filtration...
A systematic investigation into the reactions of Cd(NO3)2·4H2O with o- and p-phenylenediacetic acid within presence semi-rigid 1,4-bis(imidazol-1-ylmethyl)benzene (bimb) co-ligands under similar conditions was carried out. In this study, two novel coordination polymers containing Cd(II) ions as metal {[Cd(μ-opda)(bimb)]·DMF}n (1, opda = 1,2-phenylenediacetate) [Cd(μ-ppda)(bimb)0.5]n (2, ppda 1,4-phenylenediacetate) have been prepared structurally characterized. Furthermore, inhibitory...
A method for the determination of flavomycin in shrimp by high performance liquid
Alveolar epithelial cells (AEC) are the basis of lung structure and function.Apoptosis AEC plays a crucial role under normal pathological conditions.Acute injury exists alveolar cell apoptosis,serious destruction tissue respiratory function badly damaged. In recent years,related research suggests that adjusting for apoptosis pathways is potential method treatment acute injury. Key words: Apoptosis; Alveolar cell; Acute
Abstract Background : Impairment of lineage specification and function gonadal somatic cells can lead to disorders sexual development (DSDs) fertility defects in humans. However, little is known about the protein phosphatases testis development. Results We showed that phosphatase 4 (PPP4) could maintain SOX9 expression Sertoli play an essential role cell maintenance male fertility. Conditional deletion Ppp4c, a PPP4 catalytic subunit gene, caused reprogramming granulosa-like postnatally by...