A5041333791- Migraine and Headache Studies
- Trigeminal Neuralgia and Treatments
- Neurosurgical Procedures and Complications
- Anesthesia and Pain Management
- Glaucoma and retinal disorders
- Sympathectomy and Hyperhidrosis Treatments
- Pharmacological Effects and Toxicity Studies
- Advanced Neuroimaging Techniques and Applications
- Neurological Disorders and Treatments
- Metalloenzymes and iron-sulfur proteins
- Endometrial and Cervical Cancer Treatments
- Neuroscience of respiration and sleep
- Neuroendocrine Tumor Research Advances
- Cerebral Venous Sinus Thrombosis
- Cardiovascular Syncope and Autonomic Disorders
- IgG4-Related and Inflammatory Diseases
- Biochemical effects in animals
- Optical Coherence Tomography Applications
- Dental Anxiety and Anesthesia Techniques
- Reproductive Health and Contraception
- Ocular Diseases and Behçet’s Syndrome
- Psychosomatic Disorders and Their Treatments
- Neuroendocrine regulation and behavior
- Neuropeptides and Animal Physiology
- Nicotinic Acetylcholine Receptors Study
Balıkesir University
2014-2024
Sağlık Bilimleri Üniversitesi
2021-2024
University of Health Sciences Antigua
2024
Bursa Uludağ Üni̇versi̇tesi̇
2023
Bursa Yuksek Ihtisas Egitim Ve Arastirma Hastanesi
2023
Gazi University
2012-2021
Izmir University
2021
Gaziantep University
2019
The present study aimed to investigate the effects of selective calcitonin gene related peptide (CGRP) receptor antagonist (MK-8825) on cortical spreading depression (CSD) induced pain behavior and anxiety in freely-moving rats, neuronal activation correlated anatomical regions.CSD was while keeping all meningeal layers BBB intact MK-8825 administered two different doses. Regional cerebral blood flow (rCBF), arterial pressure DC shift were recorded. Behavioral studies conducted rats....
Abstract This study investigated the effect of repetitive cortical spreading depression ( CSD ) on behaviour and anatomical physiological patterns cellular activation subcortical areas in awake, moving rats. Rat behaviours response to events evoked by application KC l were quantified with electrophysiological recording. Immunohistochemistry was used quantify regions activation. The effects acute valproic acid administration behavioural parameters evaluated. significantly decreased locomotor...
Retinal atrophy is well known in adult-onset multiple sclerosis but remains unexplored children. We aimed to determine retinal nerve fiber layer thickness and macular volume pediatric patients, with without optic neuritis their relations visual evoked potentials. also examined changes at month 12. of all quadrants were measured 28 relapsing remitting eyes 30 control using optical coherence tomography found reduced patients compared controls. This reduction was more prominent longer time...
The present study evaluated the diagnostic accuracy of immune system algorithms with aim classifying primary types headache that are not related to any organic etiology. They divided into four types: migraine, tension, cluster, and other headaches. After we took this main objective consideration, three different neurologists were required fill in medical records 850 patients our web-based expert hosted on project web site. In evaluation process, Artificial Immune Systems (AIS) used as...
The complexity of clinical practice extends far beyond the controlled settings trials, and there is a need for real-world studies aimed at identifying which patients will respond to anti-CGRP monoclonal antibodies in different countries. This study investigate efficacy safety galcanezumab treating migraine real-life setting Turkey, as well identify predictors treatment response.A total 476 who diagnosed with according ICHD-3 criteria treated by headache specialists were voluntarily...
Abstract Background: Cerebral autosomal dominant arteriopathy with subcortical infarctions and leukoencephalopathy (CADASIL) is the most common hereditary form of cerebral small vessel disease. It clinically, radiologically, genetically heterogeneous caused by NOTCH3 mutations. Methods: In this study, we analyzed in 368 patients suspected CADASIL using next-generation sequencing. The significant variants detected were reported along clinical radiological features patients. Results:...
In this study, we aimed to compare the efficacy of greater occipital nerve (GON) block alone and GON combined with supraorbital (SON) in treatment medication overuse headache (MOH).82 patients were divided into two groups: 41 administered bilateral while other + SON block. Nerve blocks every 10 days for a total 5 sessions. After each administration 20 after last injection, information on pre post numerical rating scale (NRS) score, number painful days, analgesic intake, duration pain...
The Sphenopalatine Ganglion (SPG) is the target of interventional procedures in musculoskeletal pain, especially headaches, due to its role autonomic nervous system. Our study aimed investigate effect transnasal sphenopalatine ganglion blockade (SPGB) on functional capacity, sleep, and depression fibromyalgia patients.
Greater occipital nerve (GON) blockade injections can be used to prevent episodic and chronic cluster headaches. In recent studies, prophylactic treatment has been in addition the GON blockade. this study, we aimed elucidate effect of on attack frequency, pain intensity, duration patients diagnosed with
Immunoglobulin G4 (IgG4)-related disease is an immune-mediated, fibroinflammatory condition that causes multisystemic contrast enhancement and predominantly observed in elderly male patients. The most prominent features of IgG4-related are systemic involvement affecting from two to six systems. In the central nervous system, these enhancements typically found meninges orbit. This case study describes a 78-year-old female patient with persistent headaches constant diarrhea who underwent...
Cortical spreading depression (CSD) is implicated in migraine. Pain behavior important for experimental migraine studies.
Objective: To assess the effectiveness of sphenopalatine ganglion blockade (SPGB) as an alternative treatment for patients with chronic migraine resistant to medical treatment. Methods: In total, 23 underwent 4 sessions bilateral transnasal SPGB bi-weekly, and monthly number headache days, duration, numerical rating scale (NRS) response results were recorded. Results: Compared before SPGB, frequency attacks per month (23.66 ± 9.8 vs. 10.5 11.9 days), duration headaches (31.3 16.8 18.4 h),...
Brain areas affected during neurodegenerative disease progression are considered anatomically connected to the first areas. The dorsolateral prefrontal cortex (DLPFC) has connections with medial temporal lobe (MTL), which includes regions that become atrophic in Alzheimer’s disease. In this study, we aimed investigate degree of volumetric asymmetry DLPFC and MTL structures. This is a cross-sectional study involving 25 patients healthy adults who underwent MRI 3D turbo spin echo sequence at...
Purpose of Investigation: To evaluate the authors’ experience and clinical outcomes extraperitoneal pelvic lymph node dissection (EPLND) subsequent radiotherapy with concomitant chemotherapy in 21 patients invasive cervical cancer found simple hysterectomy. Materials Methods: The authors reviewed data occult (OICC) detected after hysterectomy carried out for benign gynecologic conditions or preinvasive lesions from 2007 to 2017. Results: All were classified into three groups as low risk,...
Objective: Tension-type headache (TTH) with an average lifetime prevalence of 46% (12-78%) in adults is the most common primary type. Acupuncture treatment one adjunctive therapy tension type so we wanted to evaluate response difference acupuncture between genders.
 Material and Methods: In this retrospective study, medical records TTH patients, aged 18 60, who did not receive conventional (patient refusing or intolerance due drug side effects) completed pre-determined sessions...