A5041562246- Neuroendocrine regulation and behavior
- Memory and Neural Mechanisms
- Primate Behavior and Ecology
- Neural dynamics and brain function
- Neural and Behavioral Psychology Studies
- Face Recognition and Perception
- Evolutionary Psychology and Human Behavior
- Child and Animal Learning Development
- Psychology of Moral and Emotional Judgment
- Olfactory and Sensory Function Studies
- Motor Control and Adaptation
- Attachment and Relationship Dynamics
- Behavioral and Psychological Studies
- Action Observation and Synchronization
- Evolutionary Game Theory and Cooperation
- Visual perception and processing mechanisms
- Functional Brain Connectivity Studies
- Stress Responses and Cortisol
- Neurotransmitter Receptor Influence on Behavior
- Epilepsy research and treatment
- Decision-Making and Behavioral Economics
- Human-Animal Interaction Studies
- Neuroscience and Neuropharmacology Research
- Cancer therapeutics and mechanisms
- Tactile and Sensory Interactions
Yale University
2016-2025
Kavli Institute for Theoretical Sciences
2019-2024
Duke University
1998-2016
Institut des Sciences Cognitives Marc Jeannerod
2012
Washington University in St. Louis
2004-2010
Merck & Co., Inc., Rahway, NJ, USA (United States)
2002-2007
Acumentrics (United States)
2004
University of Connecticut
1998
Duke Medical Center
1998
Duke University Hospital
1998
People attend not only to their own experiences, but also the experiences of those around them. Such social awareness profoundly influences human behavior by enabling observational learning, as well motivating cooperation, charity, empathy, and spite. Oxytocin (OT), a neurosecretory hormone synthesized hypothalamic neurons in mammalian brain, can enhance affiliation or boost exclusion different species distinct contexts, belying any simple mechanistic neural model. Here we show that inhaled...
A neuroethological approach to human and nonhuman primate behavior cognition predicts biological specializations for social life. Evidence reviewed here indicates that ancestral mechanisms are often duplicated, repurposed, differentially regulated support behavior. Focusing on recent research from primates, we describe how the brain might implement functions by coopting extending preexisting previously supported nonsocial functions. This reveals highly specialized have evolved decipher...
Social decisions require evaluation of costs and benefits to oneself others. Long associated with emotion vigilance, the amygdala has recently been implicated in both decision-making social behavior. The signals reward punishment, as well facial expressions gaze Amygdala damage impairs interactions, neuropeptide oxytocin (OT) influences human decisions, part, by altering function. Here we show monkeys playing a modified dictator game, which one individual can donate or withhold rewards from...
Learning about the world is critical to survival and success. In social animals, learning others a necessary component of navigating world, ultimately contributing increasing evolutionary fitness. How humans nonhuman animals represent internal states experiences has long been subject intense interest in developmental psychology tradition, and, more recently, studies decision making involving self other. this review, we explore how conceptualizes process representing others, neuroscience...
What happens to others profoundly influences our own behavior. Such other-regarding outcomes can drive observational learning, as well motivate cooperation, charity, empathy, and even spite. Vicarious reinforcement may serve one of the critical mechanisms mediating influence on behavior decision-making in groups. Here we show that rhesus macaques spontaneously derive vicarious from observing rewards given another monkey, this them subsequently deliver or withhold other animal. We exploited...
Significance Many animals perform complex intelligent behaviors, but the question of whether are aware while doing so remains a long debated unanswered question. Here, we develop new approach to assess nonhuman have awareness by utilizing well-known double dissociation visual awareness—cases in which people behave completely opposite ways when stimuli processed consciously versus nonconsciously. Using this method, found that species—the rhesus monkey—exhibits very same behavioral signature...
The sensorimotor transformations for visually guided reaching were originally thought to take place in a series of discrete transitions from one systematic frame reference the next with neurons coding location relative fixation position (gaze-centered) occipital and posterior parietal areas, shoulder dorsal premotor cortex, muscle- or joint-based coordinates motor output neurons. Recent empirical theoretical work has suggested that spatial encodings use range idiosyncratic representations...
To reach for something we see, the brain must integrate target location with limb to be used reaching. Neuronal activity in parietal region (PRR) located posterior cortex represents targets Does this representation depend on used? We found a continuum of limb-dependent and limb-independent responses: some neurons represented movements either limb, whereas others only contralateral-limb targets. Only few cells ipsilateral-limb Furthermore, these representations were not dependent preferred...
Few studies have addressed the neural computations underlying decisions made for others despite importance of this ubiquitous behavior. Using participant-specific behavioral modeling with univariate and multivariate fMRI approaches, we investigated correlates decision-making self other in two independent tasks, including intertemporal risky choice. Modeling subjective valuation indicated that participants distinguished between themselves dissimilar preferences. Activity dorsomedial...
A key feature of most social relationships is that we like seeing good things happen to others. Research has implicated the anterior cingulate cortex (ACC) in attaching value outcomes. For example, single neurons macaque ACC selectively code reward delivery self, a partner, both monkeys, or neither monkey. Here, assessed whether ACC's contribution cognition causal by testing rhesus monkeys (Macaca mulatta) on vicarious reinforcement task before and after they sustained lesions. Prior...
Social gaze interaction powerfully shapes interpersonal communication. However, compared with social perception, very little is known about the neuronal underpinnings of real-life interaction. Here, we studied a large number neurons spanning four regions in primate prefrontal-amygdala networks and demonstrate robust single-cell foundations interactive orbitofrontal, dorsomedial prefrontal, anterior cingulate cortices, addition to amygdala. Many these areas exhibited high temporal...