A5078545244- Neural and Behavioral Psychology Studies
- HIV/AIDS Research and Interventions
- HIV-related health complications and treatments
- Functional Brain Connectivity Studies
- HIV Research and Treatment
- Advanced MRI Techniques and Applications
- Mental Health Research Topics
- Visual perception and processing mechanisms
- Neuroscience and Neuropharmacology Research
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Nutritional Studies and Diet
- Metabolomics and Mass Spectrometry Studies
- Neural dynamics and brain function
- Neuroinflammation and Neurodegeneration Mechanisms
- Diet and metabolism studies
- Memory and Neural Mechanisms
- Behavioral Health and Interventions
- Health and Well-being Studies
- Cannabis and Cannabinoid Research
- Decision-Making and Behavioral Economics
- Frailty in Older Adults
- Multisensory perception and integration
- Diverse Music Education Insights
- Peripheral Artery Disease Management
- Liver Disease Diagnosis and Treatment
University of Florida
2020-2025
Florida College
2023-2025
University of Florida Health
2022
Cognitive Research (United States)
2020-2022
McKnight Brain Research Foundation
2022
Texas A&M University
2019-2020
Statistical regularities in distractor location trigger suppression of high-probability locations during visual search. The degree to which such reflects generalizable, persistent changes a spatial priority map has not been examined. We demonstrate that persists after probabilities are equalized and likely genuine reshaping the rather than more transient effects selection history. Statistically learned generalizes across contexts within task learning but does generalize between paradigms...
Attention is biased toward stimuli that have been associated with aversive outcomes in the past. This bias has previously interpreted as reflecting automatic orienting threat signals. However, many prior studies, either threatening stimulus provided valuable predictive information, signaling possibility of an otherwise unavoidable punishment and thereby allowing participants to brace themselves, or event could be avoided fast accurate task performance. Under these conditions, monitoring for...
The neurometabolic timecourse of healthy aging is not well-established, in part due to diversity quantification methodology. In this study, a large structured cross-sectional cohort male and female subjects throughout adulthood was recruited investigate changes as function age, using consensus-recommended magnetic resonance spectroscopy methods.102 volunteers, with approximately equal numbers participants each decade age from the 20s, 30s, 40s, 50s, 60s, were IRB approval. MR spectroscopic...
Abstract Age-related alterations in GABAergic function, including depletion of cortical GABA concentrations, is likely associated with declining cognitive performance normative aging. However, the extent to which function perturbed highest-functioning stratum oldest-old (85+) population unknown. For first time, we report stability this population. We extend our previously-reported Individual Participant Data Meta-Analysis levels across lifespan, integrating four large cross-sectional...
Attention prioritizes stimuli previously associated with reward or punishment. The present study examined whether this attentional bias, widely considered to be involuntary and automatic, could suppressed sufficient motivation. Participants performed visual search for a shape-defined target. One color-singleton distractor predicted the possibility of receiving another an electric shock, each outcome occurring infrequently. were informed that likelihood earn avert punishment depended on fast...
Obesity is associated with adverse effects on brain health, including an increased risk of neurodegenerative diseases. Changes in cerebral metabolism may underlie or precede structural and functional changes. While bariatric surgery known to be effective inducing weight loss improving obesity-related medical comorbidities, few studies have examined whether it able improve metabolism. In the present study, we changes metabolite concentrations participants obesity who underwent surgery....
Abstract Cortical GABA levels are reduced in older age; age-related differences may be associated with cognitive change. The nature of the highest-functioning stratum oldest-old (85+) population is not yet known. We extend our previously-reported Individual Participant Data Meta-Analysis (Porges et al., 2021) across lifespan four novel datasets sampling cognitively-intact oldest-old. slope adults flattens after roughly age 80. interpret these findings as an effect survivorship: inclusion...
Abstract Purpose The neurometabolic timecourse of healthy aging is not well-established, in part due to diversity quantification methodology. In this study, a large structured cross-sectional cohort male and female subjects throughout adulthood was recruited investigate changes as function age, using consensus-recommended magnetic resonance spectroscopy methods. Methods 102 volunteers, with approximately equal numbers participants each decade age from the 20s, 30s, 40s, 50s, 60s, were IRB...
The metabolic timecourse of healthy aging is not well-established, in part due to diversity quantification methodology. This study recruited a large structured cross-sectional cohort throughout adulthood investigate changes as function age, and applied consensus-recommended methods. Positive age correlations tCho, tCr, mI were observed for CSO PCC, while none was found tNAA, Glu or Glx either region. PCC GABA decreased with Scyllo increased, we higher female subjects. Our results establish...
Objective: To determine the association between in-vivo spectroscopy metabolite data, local connectome, and markers of initial injury severity (I.e., history loss consciousness; LoC) in traumatic brain (TBI), a heterogenous sample Veterans non-Veterans with remote mild-to-moderate TBI >6 months). Participants Methods: complete PRESS magnetic resonance (MRS) diffusion weighted imaging (DWI) data (N = 41) were sampled from larger multisite study chronic (Nmiid 38; Nmoderate 3; 54% LoC; 46%...
Stimuli associated with aversive outcomes such as shock and monetary loss automatically capture attention. In many common experimental paradigms, can be either avoided fast accurate responses or are unrelated to behavior probabilistic, meaning that the stimuli also occasional withholding of an anticipated event. It therefore remains unclear whether resulting attentional biases driven by learning from trials on which delivered (punishment learning) withheld (negative reinforcement), extension...