A5030306554- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Lung Cancer Diagnosis and Treatment
- Immune Cell Function and Interaction
- Epigenetics and DNA Methylation
- Cancer Diagnosis and Treatment
- Cancer-related gene regulation
- Neuroendocrine Tumor Research Advances
- Cancer Immunotherapy and Biomarkers
- Metastasis and carcinoma case studies
- Lung Cancer Treatments and Mutations
- Medical Imaging and Pathology Studies
- Occupational Health and Safety Research
- Lung Cancer Research Studies
- RNA modifications and cancer
- Immunotherapy and Immune Responses
- IL-33, ST2, and ILC Pathways
- Infrastructure Maintenance and Monitoring
- Advanced Mathematical Physics Problems
- Pleural and Pulmonary Diseases
- Extracellular vesicles in disease
- Advanced Steganography and Watermarking Techniques
- Medicinal Plants and Bioactive Compounds
- Inflammatory Biomarkers in Disease Prognosis
University of Science and Technology of China
2019-2025
Shanghai Jiao Tong University
2022-2024
China Southern Power Grid (China)
2024
Tongji Hospital
2022
Huazhong University of Science and Technology
2022
Xi'an Jiaotong University
2022
Anhui Medical University
2008-2021
Anhui Provincial Hospital
2008-2021
Xi'an Chest Hospital
2021
Wannan Medical College
2021
Importance The association of neoadjuvant chemoimmunotherapy (NCIT) vs chemoradiotherapy (NCRT) with tumor downstaging and survival in locally advanced esophageal squamous cell carcinoma (ESCC) remains unclear because limited evidence. Objective To compare the associations NCIT NCRT regression long-term patients ESCC. Design, Setting, Participants In this comparative effectiveness research study, from January 2016 to March 2023, ESCC who underwent esophagectomy following or were identified a...
Construction sites have complex environments and high accident rates. Human intrusion into static hazardous areas is a significant cause of accidents. Traditional engineering safety management mainly relies on manual methods, such as patrol inspection by supervisors, which time-consuming labor-intensive, it difficult to achieve complete supervision. In recent years, the emergence artificial intelligence technology computer vision has provided new scheme for detection. However, existing...
NK cells are a major component of the antitumour immune response that limits tumour progression. However, it has been reported tumour-infiltrating (TINK) from patients with non-small-cell lung carcinoma (NSCLC) exhibit profound defects in degranulation and IFN-γ production. In support this notion, we report novel mechanism associated escape cell-mediated immunity carcinoma. study, investigated phenotypic profile TINK based on expression NK-cell maturation markers CD11b CD27. Interestingly,...
In order to reveal the heat transfer performance of nanofluids in solar collectors, thermal conductivity and dynamic viscosity five kinds graphene oxide nanofluids, with a mass fraction 0.002% 0.01%, were studied temperature range 25–50 °C. To ensure dispersion stability prepared UV–Vis absorption spectrum, zeta potential particle size distribution employed for nanofluid characterization. Agglomeration sedimentation after standing 20 days observed, showing good oxide–water nanofluid. The...
Small cell carcinoma of the esophagus (SCCE) is a rare, highly aggressive tumor characterized by early dissemination and poor prognosis. Surgery, chemotherapy, radiotherapy have been used alone or in combination for treatment this rare disease. The aim retrospective study was to analyze role surgery management limited-stage SCCE at high-volume center. We retrospectively evaluated 73 patients with who received an esophagectomy our center from January 1994 December 2011. clinical...
The p53 gene has the highest mutation frequency in tumors, and its inactivation can lead to malignant transformation, such as cell cycle arrest apoptotic inhibition. Persistent high-risk human papillomavirus (HR-HPV) infection is leading cause of cervical cancer. P53 was inactivated by HPV oncoprotein E6, promoting abnormal proliferation carcinogenesis. To study treatment intraepithelial neoplasia (CIN) cancer restoring expression inactivating oncoprotein, verify effectiveness nano drugs...
From January 2018 to May 2018, 108 patients with thoracic esophageal cancer underwent esophagectomy two- three-field lymph node dissection. Serum cytokeratin 19 fragment antigen 21-1 (CYFRA21-1), squamous cell carcinoma antigen, and carcinoembryonic levels were detected before surgery. Preoperative serum of CYFRA21-1 correlated closely pN stage ( P = 0.000 0.045). pathological T status independent predictors metastasis 0.000). The area under the curve values for predicting 0.731 =0.000)...
Significance As a master transcription factor, the tumor suppressor p53 regulates variety of cellular processes by modulating target gene expression. Although well known as transcriptional activator, is also able to repress expression number protein-coding genes. However, it remains largely unknown whether long noncoding RNA (lncRNA) repression involved in regulation function. Here, we show that can transcriptionally lncRNA E2F1 messenger (mRNA) stabilizing factor (EMS) and vice versa EMS...
SAHA, a member of histone deacetylase inhibitors (HDACIs), which emerged as class novel antitumor drug, has been used in clinical treatment cancers. However, experience SAHA solid tumors disappointing. Nevertheless, the underlying mechanism this deficiency is not clearly understood. In present study, we found that could induce epithelial-mesenchymal transitions (EMT) lung cancer A549 cells, was associated with increased migration capability and cellular morphology changes. We showed...
Abstract Background Minimally invasive approaches are increasingly being used in oesophagectomy. The aim of this study was to compare the short‐term clinical outcomes minimally I vor– L ewis oesophagectomy ( MIILE ) technique with those open OILE technique. Methods We identified 131 patients who underwent combined thoracoscopy and laparoscopy. These were compared 248 between J anuary 2012 D ecember 2013. Results produced similar post‐operative hospital mortality 2.3 versus 2%; P = 1.000)....
Abstract A method of transmission highly confidential information in power communication network based on digital watermarking technology is proposed order to reduce the leakage risk and achieve purpose safe private information. This establishes data topology model connects receiving sending terminals. Digital used embed be transmitted, encrypt information, optimize DES encryption algorithm twice, so as realize The experimental results show that watermark embedding rate, decryption rate...
Purpose Workers' unsafe behavior is the main cause of construction safety accidents, thereby highlighting critical importance behavior-based management. To compensate for limitations computer vision in tackling knowledge-intensive issues, semantic-based methods have gained increasing attention field Knowledge graph provides an efficient and visualized method identification various behaviors. Design/methodology/approach This study proposes framework by integrating knowledge graph–based...
Although jejunostomy is widely used in complete thoracoscopic and laparoscopic minimally invasive Ivor-Lewis esophagectomy, its clinical effectiveness remains undefined. This study aimed to assess the therapeutic side effects of patients undergoing esophagectomy for thoracic segment esophageal carcinoma.A total 1400 with carcinoma who underwent Thoracic Surgery our hospital from 2015 2018 were retrospectively evaluated. Of these, 356 1044 treated nasojejunal feeding tubes (Nasojejunal group)...
The aim of this study was to evaluate the effect sequential pulmonary resections by uniportal video-assisted thoracoscopic surgery (VATS) for bilateral multiple nodules (BMPNs). A single-center, prospective, nonrandomized performed on patients who underwent one-stage or two-stage operations VATS. clinical, pathological and perioperative data were summarized analyzed from January 2021 December 2021. total 80 included during period. Sequential resection VATS in 40 patients. There no deaths...
Pretreatment inflammation-based biomarkers and the prognostic nutrition index (PNI) have been used to evaluate prognosis in cancer patients. However, few studies focused on value of post-treatment PNI ESCC We aimed investigate values pre/post-treatment inflammatory parameters for establishing a nomogram predict overall survival (OS) A retrospective review was performed 268 patients with esophagectomy. The indexes were evaluated. Based results multivariable Cox analysis, developed. predictive...
The therapeutic strategy for patients with spontaneous rupture of the esophagus includes surgical repair, endoscopic therapy, supportive care, and others. However, no evidence exists to direct clinical decision-making regarding choice operative nonoperative management. aim this study was determine efficacy different strategies in both general stratified patients.