A5101783730- Advanced Fiber Laser Technologies
- Solid State Laser Technologies
- Photonic Crystal and Fiber Optics
- Laser Design and Applications
- Spectroscopy and Laser Applications
- Advanced Chemical Physics Studies
- Pediatric Urology and Nephrology Studies
- Optical Imaging and Spectroscopy Techniques
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Advanced Fiber Optic Sensors
- Molecular Spectroscopy and Structure
- RNA modifications and cancer
- Ureteral procedures and complications
- Quantum, superfluid, helium dynamics
- Dermatologic Treatments and Research
- Laser-Matter Interactions and Applications
- Atmospheric Ozone and Climate
- Photorefractive and Nonlinear Optics
- Facial Nerve Paralysis Treatment and Research
- Fiber-reinforced polymer composites
- Prostate Cancer Diagnosis and Treatment
- Non-Invasive Vital Sign Monitoring
- Heart Rate Variability and Autonomic Control
- Esophageal and GI Pathology
Wuhan Sports University
2025
Zhejiang Cancer Hospital
2020-2025
Hospital Universitario de La Princesa
2024
First Affiliated Hospital Zhejiang University
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
National Engineering Research Center of Electromagnetic Radiation Control Materials
2024
Chinese People's Liberation Army
2020-2023
Sir Run Run Shaw Hospital
2013-2022
Shandong University
2016-2022
Zhejiang University
2013-2022
Importance The association of neoadjuvant chemoimmunotherapy (NCIT) vs chemoradiotherapy (NCRT) with tumor downstaging and survival in locally advanced esophageal squamous cell carcinoma (ESCC) remains unclear because limited evidence. Objective To compare the associations NCIT NCRT regression long-term patients ESCC. Design, Setting, Participants In this comparative effectiveness research study, from January 2016 to March 2023, ESCC who underwent esophagectomy following or were identified a...
Circular RNA (circRNA) is a type of circular endogenous produced by special selective splicing and participates in progression diverse diseases. However, the role circRNA clear cell renal carcinoma (ccRCC) still rarely reported.We detected lower circ-AKT3 expression ccRCC using microarray. Then, qPCR array was applied to verify between 60 tissues adjacent normal tissues, as well lines human kidney (HK-2). We investigated function vitro vivo underlying mechanisms Western blotting,...
Clear cell renal carcinoma (ccRCC) is the most lethal urological cancer and characterized by a high rate of metastasis relapse. N6-Methyladenosine (m6A) implicated in various stages development. However, thorough understanding m6A-modified lncRNAs ccRCC lacking. The results showed that METTL14 had decreased expression tissues. In addition, was negatively correlated to prognosis, stage, tumor grade. silencing shown significantly increase vitro vivo. High-throughput methylated RNA...
Abstract Materials combining efficient thermal insulation and high mechanical properties are needed in many areas of technology. Various aerogels provide a convenient design framework for insulators, but they often brittle. Furthermore, the spectrum advanced is constantly expanding while requirements to degree control three‐dimensional gel‐forming network increasing. Here, we report on biomimetic aramid nanofibers with structure replicating articular cartilage, prepared by supercritical...
Purpose: Locked nucleic acid (LNA)-modified anti-microRNAs have been demonstrated to target mesenchymal stem cells (MSCs) treat bone diseases. However, the "off-target" effect limits its clinical application. Methods: We selected specific aptamer M4 of MSCs and employed three-way junction (3WJ) as core scaffold construct nanoparticles (3WJ-M4-LNA) for delivery anti-miRNA 138. Results: Our results suggested that 3WJ-M4-LNA nanoparticles, not 3WJ-M4 or 3WJ-LNA, can specifically deliver MSCs,...
In the system of tracking and detection based on four-quadrant detector (4-QD), energy distribution incident spot blind area photosensitive surface will affect location accuracy. The current model is ideal circular Gauss spot, which makes error caused by shape easily ignored. this paper, improved, can adapt to elliptical distribution. width also added response models so that output each quadrant localization algorithm be calculated more accurately. simulation results show measurement...
This study tried to explore the molecular mechanism underlying progression of lung adenocarcinoma (LUAD) and discuss extracellular communication between cancer cells vascular endothelial cells. Roughly, differential analysis was carried out note that miR-30a-5p lowly expressed in LUAD, whereas CCNE2 highly expressed. Cell functional experiments demonstrated overexpressed led suppressed cell abilities proliferation, migration invasion. Dual-luciferase reporter gene assay RNA...
Seminoma is the most common testicular germ cell tumor worldwide and mainly occurs in 15‐35‐year‐old young men. Early studies have indicated that nuclear receptor 4 ( TR 4) first cloned from testis involved invasion metastasis of several human tumors; however, little attention paid to function seminoma. Our immunohistochemical IHC ) staining results showed patients with advanced stage tumors tended higher expression 4. Importantly, there was a significant association between elevated reduced...
The overtone band of 2ν2(l=2)←0 H+3 in the 2 μm infrared region has been observed absorption by using a difference frequency laser spectrometer. LiIO3 nonlinear optical system assembled Bawendi and bidirectional multiple path arrangement with velocity modulation have enabled us to observe 34 vibrational–rotation transitions from 5094 4557 cm−1. Liquid-N2 cooled plasmas were used for involving low rotational levels, while gaseous-N2 high up J,K=(9,9). From relative intensities transitions,...
Spontaneous spinal epidural hematoma (SSEH) is a relatively rare but potentially disabling disease, and the classical presentation of it includes an acute onset severe, sometimes radiating back or neck pain, followed by signs symptoms rapidly evolving nerve root cord compression.Here, we report 26-year-old female patient presented with weakness in bilateral lower extremities, progressing to intense paraplegia anesthesia without recent medical history trauma, infection, surgery, drug use.A...
Purpose Clear cell renal carcinoma(ccRCC) is the most common type of carcinoma. While it curable when detected at an early stage, some patients presented with advanced disease have poor prognosis. We aimed to identify key genes and miRNAs associated clinical prognosis in ccRCC. Methods The microarray datasets were obtained from Gene Expression Omnibus database. Differentially expressed (DEGs) differentially (DEMs) analyzed by using GEO2R. Then, Functional enrichment analysis was performed...
Percutaneous coronary intervention (PCI) helps treat artery disease but only provides short-term relief and doesn't stop progression. Exercise rehabilitation can improve outcomes for patients after PCI lower the risk of death new heart problems, many struggle to stick with their exercise routines. Spouses play a crucial role in supporting helping them stay committed rehabilitation. This study aims evaluate effectiveness couple-based program improving adherence among post-PCI patients. used...
A rich spectrum composed of hundreds sharp features (HWHM\ensuremath{\lesssim}20 MHz) has been observed in the fundamental Q branch solid ${\mathrm{H}}_{2}$, representing first case phase linear spectroscopy which high-resolution capabilities laser have fully exploited. These are interpreted as splittings o-${\mathrm{H}}_{2}$ pairs based on work by Hardy, Berlinsky, and Harris.