Xufeng Guo

ORCID: 0000-0001-9684-7107
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About
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Research Areas
  • Esophageal Cancer Research and Treatment
  • Esophageal and GI Pathology
  • Tracheal and airway disorders
  • Gastric Cancer Management and Outcomes
  • Lung Cancer Diagnosis and Treatment
  • Metastasis and carcinoma case studies
  • Enhanced Recovery After Surgery
  • Orthopedic Infections and Treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Dupuytren's Contracture and Treatments
  • Colorectal Cancer Surgical Treatments
  • Bioactive Compounds and Antitumor Agents
  • Surgical site infection prevention
  • Enzyme function and inhibition
  • Diabetic Foot Ulcer Assessment and Management
  • Respiratory Support and Mechanisms
  • Endoplasmic Reticulum Stress and Disease
  • Radiopharmaceutical Chemistry and Applications
  • Lymphoma Diagnosis and Treatment
  • FOXO transcription factor regulation
  • Medical Imaging and Pathology Studies
  • Genomics, phytochemicals, and oxidative stress
  • Airway Management and Intubation Techniques
  • Immune Cell Function and Interaction
  • Gas Sensing Nanomaterials and Sensors

Shanghai Chest Hospital
2017-2025

Shanghai Jiao Tong University
2017-2025

Guangdong Medical College
2024

Soochow University
2023-2024

Wuxi Ninth People's Hospital
2020-2024

Xi'an Jiaotong University
2024

Importance The association of neoadjuvant chemoimmunotherapy (NCIT) vs chemoradiotherapy (NCRT) with tumor downstaging and survival in locally advanced esophageal squamous cell carcinoma (ESCC) remains unclear because limited evidence. Objective To compare the associations NCIT NCRT regression long-term patients ESCC. Design, Setting, Participants In this comparative effectiveness research study, from January 2016 to March 2023, ESCC who underwent esophagectomy following or were identified a...

10.1001/jamasurg.2025.0220 article EN cc-by JAMA Surgery 2025-03-19

Despite the growing number of studies exhibiting an association diabetes mellitus (DM) and lung cancer progression, concrete mechanism DM aggravating has not been elucidated. The present study was to investigate whether how high glucose (HG) contributes proliferation migration non-small-cell (NSCLC) cells in vitro. In study, we confirmed that HG promoted NSCLC cells, also induced anti-apoptotic effect on cells. Moreover, inhibited expression growth arrest-specific 5 (GAS5) but elevated...

10.1042/bsr20171014 article EN Bioscience Reports 2018-01-25

Post-esophagectomy airway fistula (PEAF) is a serious complication after esophageal cancer resection. At present, the clinical characteristics, treatments and prognosis of PEAF patients remain inconclusive. We aimed to investigate these problems with through multi-center retrospective cohort study.We included consecutive who underwent esophagectomy for in seven major Chinese centers from January 2010 December 2020. Based on anatomic characteristics patients, PEAFs were divided into Union...

10.21037/tlcr-22-141 article EN Translational Lung Cancer Research 2022-03-01

Esophageal cancer remains a significant burden of lethal cancers worldwide, particularly in China. This is an annual report Shanghai Chest Hospital (SCH) on surgical treatment for esophageal patients 2017.

10.21037/jtd-24-49 article EN Journal of Thoracic Disease 2024-05-01

The present retrospective cohort study aims to evaluate the efficacy and safety of neoadjuvant immunochemotherapy for resectable esophageal cancer report preliminary short-term survival. A multicenter, was conducted concerning patients who received PD-1 agents plus platinum-based chemotherapy between January 2019 2022. primary endpoint tumor pathologic complete response (pCR) rate. Two hundred thirteen with initial stage cI-IVA were identified. resection(R0) rate 99.1%. pCR 31.9%, overall...

10.1097/js9.0000000000002011 article EN cc-by-nc-nd International Journal of Surgery 2024-08-05

ABSTRACT. Tuberculous arthritis of the elbow joint (TAEJ) is a relatively rare infectious bone and disease. Misdiagnosed owing to inconspicuous early symptoms, often has suffered serious damage at time treatment. This study retrospectively investigated clinical manifestations, population characteristics, diagnosis, surgical treatment, functional recovery tuberculosis (TB). A retrospective 40 patients was conducted. These were diagnosed with tuberculous from June 2007 August 2021 TAEJ by...

10.4269/ajtmh.24-0152 article EN American Journal of Tropical Medicine and Hygiene 2024-09-10

Nasopharyngeal carcinoma (NPC) originates in the nasopharyngeal mucosa, lateral wall of nasopharynx. A significant challenge NPC management is skull-base bone invasion (SBBI), which affects prognosis and treatment planning. Magnetic resonance imaging (MRI) primary diagnostic tool for SBBI patients; however, detection can be challenging due to complexity overlapping MRI signals.

10.21037/qims-24-265 article EN Quantitative Imaging in Medicine and Surgery 2024-09-23

Postoperative complications of esophageal cancer are important factors that affect the prognosis cancer. With development minimally invasive esophagectomy (MIE), incidence postoperative has decreased significantly. In this article, we introduce main and etiology, diagnosis, treatment complication. Anastomotic leakage is one most serious surgical complications, which always been a problem for surgeons. techniques, mechanical staplers, application enteral parenteral nutritional support,...

10.21037/shc.2018.06.10 article EN Shanghai Chest 2018-01-01

A sixty-six year-old woman came to hospital, complaining of dysphagia and weight loss.Esophagoscope showed a neoplasm between 15 20 cm from the incisors, biopsy revealed esophageal squamous cell carcinoma.Chest computed tomography (CT) that cervical wall became thicker, narrowing lumen extended downwards upper thoracic esophagus.Tumor invaded membranous parts 5th 12th rings trachea, no swollen lymph nodes were observed in mediastinum.The clinical stage was cT4N0M0 with borderline resectable...

10.21037/jgo-21-685 article EN Journal of Gastrointestinal Oncology 2021-12-01

Background: Ileocolonic interposition was an alternative method of esophageal substitution for patients whom gastric tube cannot be used.The migration anastomosis caused by the redundant ileum rarely reported.Therefore, this study reported that a patient with cancer who received esophagectomy and ileocolic via posterior mediastinum developed complication.Case Description: The complained dyspnea intermittent low fever 7 days after operation.Computed tomography (CT) scan indicated right...

10.21037/shc-22-20 article EN Shanghai Chest 2023-01-01

To explore the effects of pedicled flap combined with membrane induction technique in repairing foot and ankle wounds diabetic patients.

10.3760/cma.j.cn501225-20221212-00534 article EN PubMed 2023-04-20

Abstract Objective To investigate the feasibility and safety of early removal gastric tube thoracic drainage after minimally invasive esophagectomy. Methods A retrospective analysis was performed on 93 patients undergoing thoraco-laparoscopic assisted esophagectomy between January 2022 September 2022. All were divided into two groups, group conventional group. The differences in volume first day operation, days indwelling, replacement, incidence rate pleural effusion, atelectasis,...

10.1007/s44178-023-00052-x article EN cc-by Holistic Integrative Oncology 2023-08-04

Abstract: The concept and pattern of enhanced recovery after surgery (ERAS) have been used for nearly 20 years. However, the clinical application popularization ERAS in esophagectomy greatly restricted due to complexity operation high incidence postoperative complications. In recent years, with growing maturity minimally invasive technique thoracic laparoscopy, attention tissue organ protection, improvement making gastric tube presentation new concepts, has made a breakthrough field...

10.21037/shc.2018.06.07 article EN Shanghai Chest 2018-01-01

Abstract Background Access to the cervicothoracic junction, whether by lower anterior cervical or transthoracic approach, is particularly difficult. It has been found that cervicosternotomy allows exposure of upper thoracic esophagus level carina. Our goal in this study summarize experience resection segment through cervicosternal splitting approach combined with laparoscopy and discuss choice surgical clearance lymph node treatment postoperative complications. Methods From January 2016...

10.1093/dote/doy089.ps01.088 article EN Diseases of the Esophagus 2018-09-01

Objective: To evaluate the safety and effectiveness of esophageal replacement with ileocolon graft. Methods: Totally 34 cases graft from July 2015 to November 2017 at Department Thoracic Surgery, Shanghai Chest Hospital, Jiaotong University were analyzed retrospectively, including 24 male 10 female, aging 7 72 years old. Esophageal by right and/or middle colic artery as a blood supply using retrosternal route except one subcutaneous route. The primary disease, postoperative complication rate...

10.3760/cma.j.issn.0529-5815.2018.e011 article EN PubMed 2018-04-01

Objective To investigate the distribution of pathogenic bacteria in wounds patients with orthopaedic incision infection, and to analyze expression levels autophagy-associated protein microtubule-binding light chain protein-3 (LC-3), autophagy-specific gene-1 (Beclin-1) ubiquitin-binding (P62) infection. Methods Total 276 treated Xi’an Ninth Hospital from May 2014 August 2017 were selected as research subjects, 40 stage infection observation group, was analyzed. While 36 cases...

10.3877/cma.j.issn.1674-1358.2020.01.011 article EN Chin J Exp Clin Infect Dis (Electronic Edition) 2020-02-15

There are few studies on the impact of body position variations in circulation and breathing, it has not been confirmed whether changes can reduce pulmonary complications thoracoscopic-assisted oesophagectomy.A single-center retrospective study included patients undergoing oesophagectomy prone or semiprone between 1 July 2020, 30 June 2021, at Shanghai Chest Hospital. were 103 with final analysis, including 43 position. Postoperative complication (PPC) incidence was primary endpoint. The...

10.3389/fonc.2022.919910 article EN cc-by Frontiers in Oncology 2022-08-09
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