Zhongping Gu

ORCID: 0000-0002-3564-0943
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About
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Research Areas
  • Lung Cancer Treatments and Mutations
  • Lung Cancer Diagnosis and Treatment
  • Gastric Cancer Management and Outcomes
  • Congenital Diaphragmatic Hernia Studies
  • Esophageal and GI Pathology
  • Esophageal Cancer Research and Treatment
  • Pectus Deformity Diagnosis and Treatment
  • Appendicitis Diagnosis and Management
  • Gastrointestinal Tumor Research and Treatment
  • Cervical and Thoracic Myelopathy
  • Medical Research and Treatments
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Abdominal Surgery and Complications
  • Respiratory Support and Mechanisms
  • Urological Disorders and Treatments
  • Pancreatic function and diabetes
  • Colorectal Cancer Treatments and Studies
  • Telomeres, Telomerase, and Senescence
  • Cancer Genomics and Diagnostics
  • Gastroesophageal reflux and treatments
  • Myofascial pain diagnosis and treatment
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Pleural and Pulmonary Diseases
  • HER2/EGFR in Cancer Research
  • Pathogenesis and Treatment of Hiccups

Shanghai Jiao Tong University
2024

Air Force Medical University
2007-2024

Tang Du Hospital
2024

Shanghai Chest Hospital
2024

Ningbo College of Health Sciences
2022

The benefit of neoadjuvant camrelizumab plus chemotherapy for resectable stage IIIA or IIIB non-small cell lung cancer (NSCLC) remains unknown.To assess the efficacy and safety vs alone patients with NSCLC.In this randomized phase 2 clinical trial conducted at hospitals in China, aged 18 to 70 years (T3N2) NSCLC were enrolled between April 7, 2020, January 12, 2022.Patients randomly assigned receive 3 cycles (200 mg) (nab-paclitaxel, 130 mg/m2, platinum [cisplatin, 75 mg/m2; carboplatin,...

10.1001/jamaoncol.2023.2751 article EN cc-by JAMA Oncology 2023-08-03

The purpose of this report was to discuss a new surgical procedure in treating esophageal stent related large tracheoesophageal fistula without tracheal resection.Clinical records 5 patients with stent-related fistulas treated hospital between 1997 and 2006 were reviewed.All had insertion covered self-expanding stent, 1 for benign stricture 4 perforation resulting from various causes. A double patch technique, which the wall used as protective repairing defect on trachea, performed an...

10.1016/j.jtcvs.2008.07.050 article EN publisher-specific-oa Journal of Thoracic and Cardiovascular Surgery 2009-01-19

Background: Alterations in MET exon 14 (METex14) and its flanking intronic regions have been identified a variety of cancers.Patients with METex14 alterations often benefit from inhibitors such as crizotinib.Given the unique mutation profiles Chinese lung cancer patients, it is necessary to investigate prevalence large cohort patients.Patients methods: Cases carrying were screened 26,391 patients by next-generation sequencing (NGS), clinicopathologic molecular characteristics...

10.7150/jca.49391 article EN cc-by-nc Journal of Cancer 2020-12-16

Neurogenic cervical spondylosis is the most common type of spondylosis, accounting for approximately 60% percent incidence spondylosis. Cervical spine Long manipulation and sling exercise training (SET) have obtained good therapeutic results in clinical rehabilitation. The aim this study was to evaluate effect combined with SET on neurogenic In assessor-blind, randomized controlled trial, 90 eligible patients will be into a combination treatment group (Long SET), conventional massage group....

10.1097/md.0000000000028861 article EN cc-by-nc Medicine 2022-03-04

The aim of this study was to evaluate the efficacy and safety non-thoracoscopic extrapleural approach Nuss procedure for correction pectus excavatum in children.From October 2007 January 2009, 42 patients with were treated Tangdu Hospital, Xi'an, China, surgical through procedure. Among them, 20 underwent a thoracoscopic guidance, other 22 approach, which bilateral tunnel edge sternum created using blunt dissection thoracic skin incisions. Without introducing thoracoscopy into cavity, steel...

10.1016/j.ejcts.2009.08.024 article EN European Journal of Cardio-Thoracic Surgery 2009-09-24

As acute lung injury (ALI) caused high mortality rate, it is important to explore the protection and treatment of ALI. The aim current study evaluate effect low molecular weight heparin (LMWH) nebulization on attenuating associated mechanism.The arterial blood gas, total protein content in bronchoalveolar lavage fluid, wet/dry ratio, malondialdehyde (MDA) content, superoxide dismutase (SOD) glutathione peroxidase (GSH-Px) activity, Akt phosphorylation were evaluated after ALI rabbits treated...

10.1155/2017/3169179 article EN cc-by BioMed Research International 2017-01-01

The current grading system only includes six pathological subtypes. In clinical work, we would encounter mucinous adenocarcinoma and mixed containing both non-mucinous adenocarcinoma. And none of these types can be applied with systems to classify risk levels predict prognosis. This retrospective study included 553 patients lung invasive or without LIMA components (stage I–III) from Shanghai Chest Hospital 6962 in the SEER database. We introduced re-classified IASLC system. validity revised...

10.1016/j.esmoop.2024.102688 article EN cc-by-nc-nd ESMO Open 2024-03-01

The present retrospective cohort study aims to evaluate the efficacy and safety of neoadjuvant immunochemotherapy for resectable esophageal cancer report preliminary short-term survival. A multicenter, was conducted concerning patients who received PD-1 agents plus platinum-based chemotherapy between January 2019 2022. primary endpoint tumor pathologic complete response (pCR) rate. Two hundred thirteen with initial stage cI-IVA were identified. resection(R0) rate 99.1%. pCR 31.9%, overall...

10.1097/js9.0000000000002011 article EN cc-by-nc-nd International Journal of Surgery 2024-08-05

The increasing incidence and mortality associated with lung cancer (LC) is a significant global health challenge. underlying mechanisms contributing to LC remain inadequately understood. However, emerging evidence suggests that the epigenetic modifier protein arginine methyltransferase 5 (PRMT5) plays complex role in various cellular processes, including DNA repair, gene transcription, alternative splicing, through its function catalyzing symmetric dimethylation of both histone non-histone...

10.3389/fonc.2024.1478672 article EN cc-by Frontiers in Oncology 2024-11-29

Video-Assisted Thoracic Surgery (VATS) lobectomy is well established and performed all around the world. With growing experience with technique, it now generally accepted that outcome of a VATS procedure at least as good as, even more superior to via traditional thoracotomy (1). Compared open surgery, may provide patients lower rate morbidity mortality, reduced pain, shorter length stay, better pulmonary function, earlier return regular activities without compromising quality procedures (2).

10.3978/j.issn.2072-1439.2013.07.33 article EN PubMed 2013-08-01

A case of esophageal lipoma resembling a paraesophageal omental herniation is described herein. 68-year-old male with symptoms epigastric gas pains was noted. barium swallow examination showed large mass in the lower esophagus, which could move up and down along esophagus easily intermittently. Computed tomography scan chest upper abdomen demonstrated fatty like density at thoracic esophagus. left posterior-lateral thoracotomy performed. Histological revealed mature lipocytes diagnosed....

10.1258/rsmsmj.54.3.58c article EN Scottish Medical Journal 2009-08-01

Objective The aim of this study was to evaluate the efficacy and safety approach Nuss procedure for correction pectus excavatum in children without thoracoscopy.Methods From Oct 2007 May 2009,48 patients with underwent procedure.Among them 22 were done under thoracoscopic guidance,and other 26 a non-thoracoscopic way,in which,a bilateral extrapleural tunnel edge sternum created using blunt dissection via thoracic skin incision.Without introducing thoracoscopy into cavity,a steel bar inserted...

10.3760/cma.j.issn.1001-4497.2010.03.010 article EN Chinese Journal of Thoracic and Cardiovaescular Surgery 2010-06-18
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