A5012998605- Lung Cancer Diagnosis and Treatment
- Carcinogens and Genotoxicity Assessment
- Calpain Protease Function and Regulation
- Tracheal and airway disorders
- Retinoids in leukemia and cellular processes
- Acute Lymphoblastic Leukemia research
- Arsenic contamination and mitigation
- Air Quality and Health Impacts
- RNA regulation and disease
- Adipose Tissue and Metabolism
- Amoebic Infections and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Effects and risks of endocrine disrupting chemicals
- Birth, Development, and Health
- Bone and Dental Protein Studies
- Energy and Environment Impacts
- Epigenetics and DNA Methylation
- SARS-CoV-2 and COVID-19 Research
- Parasitic infections in humans and animals
- Meat and Animal Product Quality
- Biotin and Related Studies
- Cell death mechanisms and regulation
- dental development and anomalies
- Cancer-related Molecular Pathways
- Medical Imaging and Pathology Studies
Universidad Nacional Autónoma de México
2015-2025
University of Chile
2019
Pontificia Universidad Javeriana
2019
Janssen (United States)
2017
Universidad del Rosario
2014
Instituto Venezolano de Investigaciones Científicas
2013
City of Knowledge
2012
Instituto de Investigaciones Científicas y Servicios de Alta Tecnología
2012
University of Louisville
2009
Thomas Jefferson University Hospital
1993-2004
One of the indications for rapidly expanding use thoracoscopic surgery as an alternative to thoracotomy is excision peripheral lung nodules. Nodules judged too small or far from pleural surface be seen palpated during thoracoscopy must localized beforehand. The purpose this study was evaluate feasibility and effectiveness percutaneous placement spring hookwires localize such nodules before video-assisted thoracoscopy.Under CT guidance, 17 in 14 patients were preoperatively with Kopans breast...
Abstract Successful treatment of neoplastic disease has been impeded by the lack therapeutic agents which specifically destroy tumor cells. Enzymes selectively deplete substrates required cells, but not normal tissue, could improve indices dramatically. Presently, microbial asparaginases are used clinically for treating acute lymphocytic leukemia. While these enzymes should cells and spare tissues, their use is accompanied many toxic effects immunosuppression. The administration Escherichia...
Abstract A viable strategy for addressing the aflatoxin issue using two enterosorbents prepared from marigold petals and guava leaves was validated. The were characterized via Fourier transform infrared spectroscopy (FTIR), field-emission scanning electron microscopy (FESEM), energy dispersive X-ray fluorescence (EDS), diffraction (XRD) to obtain information about surface functional groups, microstructure, multi-elemental composition, degree of crystallinity, phase analysis. potential in...
PURPOSE: To evaluate incidental pulmonary emboli detected at helical computed tomography (CT) and the effect on patient care. MATERIALS AND METHODS: A computer search of reports from 1,879 consecutive contrast material-enhanced CT scans identified 28 cases in which were suggested. These rereviewed by three radiologists to confirm intraluminal defects. Six excluded (three because tumor invasion, two arterial stump thrombi after pneumonectomy, one artifact). In four cases, clinically suspected...
Amelogenesis imperfecta (AI) is a group of enamel development disorders that alter the structure and chemical composition tissue. There great variability in clinical presentation; according to Witkop, AI can be categorized into 14 subtypes, which makes its diagnosis extremely complex.This study aimed describe determine frequency radiographic features inheritance patterns found 41 Chilean families diagnosed with diverse types AI.We analyzed records, photographs, pedigrees radiographs 121...
Heat shock proteins (HSP) genes are a superfamily responsible for encoding highly conserved that important antigen presentation, immune response regulation, and cellular housekeeping processes. These can be increased by stress related to pollution, example, smoke from biomass burning and/or tobacco smoking. Single nucleotide polymorphisms (SNPs) in these could affect the levels of their proteins, as well susceptibility developing lung diseases, such chronic obstructive pulmonary disease...
The relationship of thoracic lymphadenopathy to pulmonary interstitial disease in diffuse and limited systemic sclerosis: CT findings.R J Wechsler, R M Steiner, P W Spirn, S Rubin, A Salazar, Shah, K Russell, Jimenez VargaAudio Available | Share
Smoking and smoke from biomass burning (BB) are the main environmental risk factors for COPD. Clinical differences have been described between COPD related to smoking wood smoke, but no studies shown genetic patients exposed these two factors.To investigate a possible association of tumor necrosis factor (TNF) promoter polymorphisms, we conducted case-control study. A total 1,322 subjects were included in four groups: with diagnosis secondary (COPD-S, n=384), (COPD-BB, n=168), smokers...
The standard treatment for glioblastoma multiforme (GBM) is surgery followed by chemo/radiotherapy. A major limitation on patient improvement the high resistance of tumors to drug treatment, likely responsible their subsequent recurrence and rapid progression. Therefore, alternatives therapy are necessary. aim present study was evaluate whether mifepristone, an antihormonal agent, has a synergistic effect with temozolomide (used in gliomas). Whereas mechanism involves damage tumor DNA...
Studies associate particulate matter (PM) exposure with pulmonary, cardiovascular, and neurologic diseases. Elevated levels of coarse (PM10) fine (PM2.5) PM have been reported in the Mexico City metropolitan area during last two decades. There is limited information if these conditions affect newborns. We associated maternal to by monitoring stations considering place residence each participant presence genotoxic damage (cytome analysis) umbilical cord blood (UCB) lymphocytes. Eighty‐four...
SummaryGastric inhibitory polypeptide (GIP) induces dose-dependent increases in superior mesenteric blood flow the anesthetized cat. There was no concommitant change systemic arterial pressure or femoral indicating a specific decrease vascular resistance.
A study was realized to ascertain whether eight selected pesticides would induce double strand breaks (DSB) in lymphocyte cultures and this damage greater levels of proteins Rad51 participating homologous recombination or p-Ku80 nonhomologous end joining. Only five were found DSB which only glyphosate paraoxon induced a significant increase protein, indicating that joining recombinational DNA repair system be activated. The type gamma-H2AX foci observed comparable by etoposide at similar...