A5054298712- Glaucoma and retinal disorders
- Retinal Imaging and Analysis
- Retinal Diseases and Treatments
- Ophthalmology and Visual Impairment Studies
- Retinal and Optic Conditions
- Corneal surgery and disorders
- Neurological Disorders and Treatments
- Connexins and lens biology
- Spatial Neglect and Hemispheric Dysfunction
- Blood Pressure and Hypertension Studies
- Alzheimer's disease research and treatments
- Ophthalmology and Visual Health Research
- Retinopathy of Prematurity Studies
- Circadian rhythm and melatonin
- Ophthalmology and Eye Disorders
- Trace Elements in Health
- Cerebral Venous Sinus Thrombosis
- Multiple Sclerosis Research Studies
- Pain Mechanisms and Treatments
- Nerve injury and regeneration
- Facial Trauma and Fracture Management
- Infrared Thermography in Medicine
- Cardiovascular Health and Disease Prevention
Sun Yat-sen University
2020-2025
Massachusetts Eye and Ear Infirmary
2020-2024
Smith-Kettlewell Eye Research Institute
2020-2024
Harvard University
2020-2023
Leipzig University
2020-2021
Zhongshan Ophthalmic Center, Sun Yat-sen University
2019-2020
Abstract Aims/hypothesis As the prevalence of insulin resistance and glucose intolerance is increasing throughout world, diabetes-induced eye diseases are a global health burden. We aim to identify distinct optical bands which closely related metabolism, using non-invasive, high-resolution spectral domain coherence tomography (SD-OCT) in large, population-based dataset. Methods The LIFE-Adult-Study randomly selected 10,000 participants from population registry Leipzig, Germany....
Development of novel therapeutics for retinal ganglion cells (RGCs) protection and axon regeneration in neurodegenerative diseases, example, glaucoma, are critical challenges clinical treatment. Utilization N, N', N'-tetrakis-(2-Pyridylmethyl) ethylenediamine (TPEN), a specific chelator Zn2+, revealed positive medical potentials. However, its therapeutic effect promoting RGCs survival is restricted due to the inefficient drug delivery limited absorption. To address this, this work developed...
The purpose of this study was to determine the influence optic nerve head (ONH) rotation and tilt on structure-function (S-F) relationship differences between early open-angle glaucoma (OAG) with without high myopia (HM). A total 164 eyes, including 69 highly myopic (HMG) 60 OAG 35 healthy HM were included. All eyes underwent spectral-domain optical coherence tomography, standard automated perimetry, fundus photography simultaneously. S-F relationships analyzed by comparing peripapillary...
Circumpapillary retinal nerve fiber layer thickness (RNFLT) measurement aids in the clinical diagnosis of glaucoma. Spectral domain optical coherence tomography (SD-OCT) machines measure RNFLT and provide normative color-coded plots. In this retrospective study, we investigate whether percentiles (pRNFLT) from Spectralis SD-OCT improve prediction glaucomatous visual field loss over raw RNFLT.
Purpose: To develop and test machine learning classifiers (MLCs) for determining visual field progression. Methods: In total, 90,713 fields from 13,156 eyes were included. Six different progression algorithms (linear regression of mean deviation, linear the index, Advanced Glaucoma Intervention Study algorithm, Collaborative Initial Treatment pointwise [PLR], permutation PLR) applied to classify each eye as progressing or stable. MLCs (logistic regression, random forest, extreme gradient...
To assess 3-dimensional surface shape patterns of the optic nerve head (ONH) and peripapillary retinal fiber layer (RNFL) in glaucoma with unsupervised artificial intelligence (AI).
Purpose: Artificial intelligence (AI) methods are changing all areas of research and have a variety capabilities analysis in ophthalmology, specifically visual fields (VFs) to detect or predict vision loss progression. Whereas most the AI algorithms implemented Python language, which offers numerous open-source functions algorithms, majority VF offered R language. This paper introduces PyVisualFields, developed package address this gap make available Methods: For first version, libraries for...
While research has associated parental visual functions with child vision, little is known about whether dysfunction related to early childhood development (ECD) outcomes other than vision. Considering that parents conditions may encounter difficulties in engaging some daily activities, the children of these possibly have fewer opportunities acquire and refine certain ECD skills. This explores associations between different a community sample families from Beijing, China. Participants were...