A5103174124- Soybean genetics and cultivation
- Legume Nitrogen Fixing Symbiosis
- Agronomic Practices and Intercropping Systems
- Nematode management and characterization studies
- Plant responses to water stress
- Seed Germination and Physiology
- Plant pathogens and resistance mechanisms
- Plant Virus Research Studies
- Ion Transport and Channel Regulation
- Plant and Fungal Interactions Research
- Foreign Body Medical Cases
- Flowering Plant Growth and Cultivation
- Protein Hydrolysis and Bioactive Peptides
- Plant Disease Resistance and Genetics
- Esophageal and GI Pathology
- Cholesterol and Lipid Metabolism
- Synthesis of Indole Derivatives
- Genomics and Rare Diseases
- Plant Stress Responses and Tolerance
- Advanced Breast Cancer Therapies
- Cellular transport and secretion
- Soft tissue tumors and treatment
- Renal function and acid-base balance
- Moyamoya disease diagnosis and treatment
- Phagocytosis and Immune Regulation
Hokkaido Research Organization
2014-2025
Nagoya City University
2019-2023
Yokohama National University
2023
Nagoya Ekisaikai Hospital
2022
Mizuho (Japan)
2022
Takeda (Japan)
2021
Toyohashi Municipal Hospital
2017-2019
Ritsumeikan University
2019
Novartis (Japan)
2019
Mie University
2016
FLOWERING LOCUS T (FT) is an important floral integrator whose functions are conserved across plant species. In soybean, two orthologs, FT2a and FT5a, play a major role in initiating flowering. Their expression response to different photoperiods controlled by allelic combinations at the maturity loci E1 E4, generating variation flowering time among cultivars. We determined molecular basis of quantitative trait locus (QTL) for linkage group J (Chromosome 16). Fine-mapping delimited QTL...
The number and distribution of branches in soybean plants influence seed yield through effects on the efficiency light utilization as well tolerance to lodging. We have developed recombinant inbred lines (RILs) from a cross between two experimental determinant lines, which differ branching number. 172 RILs were divided into four maturity groups according their alleles for loci, E1 E3, planted separately avoid confounding competition. late-maturity RIL with genotype grown different locations,...
Lodging tolerance (LT) is an important trait for high yield and combine-harvesting efficiency in soybean [Glycine max (L.) Merr.]. Many previous studies have investigated quantitative loci (QTLs) lodging score (LS) soybean. Most of the QTLs were located proximal region maturity or growth habit loci. The aim this study was to identify genetic factors LT not associated with habit. QTL analysis performed using a recombinant inbred line (RIL) population derived from cross between 'Toyoharuka'...
Gastric glomus tumors are rare submucosal mesenchymal tumors. Because gastric and resemble gastrointestinal stromal (GISTs), preoperative diagnosis is difficult. We present a case of tumor that was removed by laparoscopy endoscopy cooperative surgery (LECS). A 67-year-old female taken to the emergency room at our hospital due epigastric pain. An upper revealed (SMT) located in lesser curvature body stomach. Endoscopic ultrasonography an intraluminal hypoechoic third or fourth layer stomach...
In Hokkaido, northern Japan, soybean [Glycine max (L.) Merr.] crops are damaged by cold weather. Chilling temperatures result in the appearance of cracking seeds (CS) crops, especially those grown eastern and Hokkaido. Seed coats CS severely split on dorsal side, cotyledons exposed frequently separated. occurrence causes unstable production because these have no commodity value. However, little is known about phenomenon. The aims this study were to identify cold-sensitive stage associated...
Five isolates of Cucumber mosaic virus (CMV) from Lilium sp. (lily), which were isolated specimens in Japan, Korea and Taiwan, unable to support satellite RNA (satRNA) accumulation. In order map the CMV sequences that are involved satRNA support, HL-CMV (Japanese lily isolate), Y-CMV (ordinary strain) Y-satellite (Y-sat) used as source material. The pseudorecombinants between revealed RNA1 was essential for replication lily. results chimeric constructs various mutations showed two amino acid...
Early maturity is an important trait for soybean [Glycine max (L.) Merr.] growing in Hokkaido where the period restricted because of short fall season and early snowfall. Development early-maturing line without decreased seed yield difficult positive correlation between days to yield. In this study, we developed two breeding lines, Tokei 1067 (T1067) Toiku 251 (T251), that were derived from crosses Japanese Polish cultivars. T1067 T251 had a significantly earlier maturing time than...
ABSTRACT In Hokkaido, northern Japan, soybean [ Glycine max (L.) Merr.] crops are damaged by cold weather. Chilling temperatures result in the appearance of cracked seeds (CSs) crops, especially those grown eastern and Hokkaido. The seed coats CSs severely split on dorsal side, cotyledons exposed frequently separated. occurrence causes unstable production because these have no commodity value. aims this study were to identify quantitative trait loci (QTL) associated with CS tolerance. a...
ABSTRACT Cold weather damages soybean [ Glycine max (L.) Merr.] crops in high‐latitude countries. The decreased seed yields caused by low temperatures are attributed to three main factors: poor growth during the early stage, abscission of flowers and pods at flowering insufficient grain filling pod‐filling stage. is most important factor that contributes reduced yields. There differences chilling tolerance among cultivars developed Japan This study screened for chilling‐tolerant (CT)...
Abstract A two‐compartment system (NICOPELIQ; NICO, Terumo Co., Tokyo, Japan) has recently been developed to neutralize icodextrin peritoneal dialysis fluid (PDF). In this study, a nonclinical evaluation of NICO was carried out evaluate biocompatibility as well water transport ability. Glucose degradation products (GDPs) in the PDFs were analyzed via high‐performance liquid chromatography (HPLC). The cell viability human mesothelial cells derived from effluent (PDE‐HPMCs) evaluated amount...
Abstract SLC26A4 is a known iodide transporter, and localized at the apical membrane of thyrocytes. Previously, we reported that SLC26A7 also involved in transport Slc26a7 novel causative gene for congenital hypothyroidism. However, its detailed role vivo remains to be elucidated. We generated mice were deficient Slc26a4 delineate differences associations their roles transport. −/− showed goitrous hypothyroidism mild growth failure on normal diet. with low iodine environment marked failure....
Abstract Recently, whole-exome sequencing (WES) has been used for genetic diagnoses of patients who remain otherwise undiagnosed. WES was performed in 177 Japanese with undiagnosed conditions were referred to the Tokai regional branch Initiative on Rare and Undiagnosed Diseases (IRUD) (TOKAI-IRUD). This study included only had not previously received genome-wide testing. Review meetings specialists various medical fields held evaluate diagnosis each case, which based guidelines American...
Lodging tolerance is an important trait of soybean [ Glycine max (L.) Merr.] that affects yield stability and combine‐harvesting efficiency. Previously, a quantitative locus analysis lodging scores was performed using recombinant inbred lines developed by crossing the lodging‐susceptible cultivar Toyomusume with lodging‐tolerant Toyoharuka, major qLS19‐1 identified. However, morphological traits associated remain unclear. To develop high‐precision DNA markers for , it necessary to identify...
In Hokkaido, the northernmost region of Japan, soybean [Glycine max (L.) Merr.] crops are damaged by cold weather. Chilling temperatures negatively affect seed appearance causing coat discoloration around hilum region, which is called cold-induced (CD). An assay for CD tolerance using a phytotron was developed, and two quantitative trait loci (QTLs) associated with were identified. The major QTL located in proximal I locus, structural variation this locus can serve as useful DNA marker, Ic...
ABSTRACT Soybean [ Glycine max (L.) Merr.] develops inflorescence meristems on each node, including the shoot apex. The flower clusters of soybean raceme have a highly branched structure, and their racemes are classified as terminal, primary, secondary, so on. Raceme phenotype is an important trait associated with number floral buds pods, dependent genotype. breeding line 1532–1 was characterized by remarkably long at apex main stem. To identify quantitative loci (QTLs) conditioning terminal...
Abstract Organophotoredox-catalyzed oxidative generation of o-quinone methides (o-QMs) for inverse-electron-demand [4+2] cycloaddition reactions has been developed. One-electron oxidation 2-(sulfanylmethyl)phenols by thioxanthylium photoredox catalyst generated o-QMs, which reacted with various styrenes to produce chromanes high regioselectivity. This reaction offers a valuable approach in situ generating o-QMs via one-electron process under irradiation mild green light.