- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- Liver Disease and Transplantation
- Gallbladder and Bile Duct Disorders
- Liver Disease Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Dysphagia Assessment and Management
- Biliary and Gastrointestinal Fistulas
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Gastroesophageal reflux and treatments
- Organ Transplantation Techniques and Outcomes
- Pancreatitis Pathology and Treatment
- Tracheal and airway disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Gastrointestinal Tumor Research and Treatment
- Intraperitoneal and Appendiceal Malignancies
- Intestinal Malrotation and Obstruction Disorders
- Intestinal and Peritoneal Adhesions
- Genetic factors in colorectal cancer
- Hepatitis C virus research
- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Esophageal Cancer Research and Treatment
- Eosinophilic Esophagitis
Franciscan Health
2022-2025
Bellevue Hospital Center
2023
Virginia Mason Medical Center
2019-2022
Troy Gastroenterology
2022
Kaiser Permanente
2022
University of Iowa Hospitals and Clinics
2016-2020
University of Arkansas for Medical Sciences
2014-2018
University of Iowa
2017
University of Arkansas at Little Rock
2015
Yahoo (United Kingdom)
2015
Objectives: Diagnosing minimal hepatic encephalopathy (MHE) is challenging, and point-of-care tests are needed. Stroop EncephalApp has been validated for MHE diagnosis in single-center studies. The objective of the study was to validate a multicenter study. Methods: Outpatient cirrhotics (with/without prior overt (OHE)) controls from three sites (Virginia (VA), Ohio (OH), Arkansas (AR)) underwent two gold standards, psychometric score (PHES) inhibitory control test (ICT)....
Postmenopausal women with nonalcoholic steatohepatitis are at an increased risk of hepatic fibrosis compared premenopausal women. Whether duration estrogen deficiency in postmenopausal state dictates individual's remains uninvestigated. We assessed the associations age menopause and time from severity fatty liver disease. Data 488 (1) histologic diagnosis disease (2) self‐reported information on were analyzed. The premature (age <40 years) study enrollment ‐ menopause, (stage 0‐4) using...
Expert endoscopists previously reported ERCP outcomes for the first commercialized single-use duodenoscope. We aimed to document usability of this device by with different levels experience.Fourteen "expert" (>2000 lifetime ERCPs) and 5 "less-expert" performed consecutive ERCPs in patients without altered pancreaticobiliary anatomy. Outcomes included completion intended indication, rate crossover another endoscope, performance ratings, serious adverse events.Two hundred including 81 (40.5%)...
<b><i>Background:</i></b> Only a small proportion of patients with biliary tree infection grow microorganisms in blood cultures. Antibiotics chosen or tailored based on organisms identified cultures have potential for under-treatment and unfavorable outcomes, including recurrent early stent occlusion. In our current practice, we collect bile culture if an Endoscopic Retrograde Cholangio-Pancreatography (ERCP) is performed suspected cholangitis. this study, compare the...
Summary Background Guidelines recommend withholding sofosbuvir ( SOF ) in patients with an estimated glomerular filtration rate eGFR of less than 30 mL/min. Aim To assess the risk acute kidney injury AKI no renal contraindications for ‐based treatment. Methods This multicenter retrospective observational study included all consecutive that were treated or telaprevir/boceprevir (TVR/BOC)‐based regimens at two tertiary university centers North America. was defined as increase ≥0.3 mg/ dL...
Abstract Background Interval colorectal cancers may be associated with a low serrated polyp detection rate (SDR) and advanced adenoma (AADR). We aimed to determine the SDR AADR for endoscopists in United States multicenter cohort. Methods included average-risk screening colonoscopies from five medical centers States. Endoscopists data on at least 100 were included. calculated median adequate rates (ADRs) > 25 %. analyzed relationship between ADR SDR, using nonparametric Spearman...
Myasthenia gravis (MG) is a neuromuscular disorder that typically affects the ocular, bulbar, neck, proximal limbs and respiratory muscles. Dysphagia can occasionally be only presenting symptom leading to extensive but ultimately futile gastrointestinal workup. Delay in diagnosis use of certain pharmacological agents interim lead myasthenic crisis, which though diagnostic life threatening. We document case dysphagia as myasthenia, diagnosed after magnesium infusion precipitated crisis. A...
Peroral endoscopic myotomy (POEM) is a novel procedure for the treatment of achalasia and spastic esophageal disorders. Experience with POEM limited, but its reported outcomes are excellent. It deemed safe even patients prior interventions.This retrospective review included who underwent at tertiary US center. was performed in multidisciplinary approach by advanced endoscopists foregut surgeons. Clinical success defined as post-POEM Eckardt score ≤3.A total 125 were included. Median...
Hypermagnesemia is a rare and under-recognized cause of paralytic ileus. We report case 21-year-old primigravida who was managed aggressively for preeclampsia presented with postpartum Detailed history employed to consider hypermagnesemia-induced ileus as the working diagnosis, patient improved correction electrolyte imbalance. Hypermagnesemia-induced lethargy, decreased reflexes, muscle weakness, flaccid paralysis, respiratory cardiac arrest are well-described; however, intestinal smooth...
Russell body gastritis (RBG) is a rare entity with unestablished pathophysiology, endoscopic findings, clinical manifestations and treatments. Literature scarce on this unclear significance. Of 18 cases reported, 12 tested (+) for Helicobacter pylori improved treatment, but it remains whether link coincidental or bears some We describe case of elderly woman who had follow-up oesophagogastroduodenoscopy chronic peptic ulcers, biopsy showed positive immunohistochemical stains κ λ, indicating...
Tracheobronchopathia osteochondroplastica (TPO) is a rare disorder characterised by development of cartilaginous and bony nodules in the trachea. It usually affects elderly males with total prevalence disease reported to be around 0.1%. Even though multiple theories associations have been described, exact cause remains unknown. Its presentation non-specific many cases being diagnosed incidentally. Chronic cough dyspnoea are most common presenting symptoms, but some may present severe airway...
<b><i>Background/Aims:</i></b> Serious gastrointestinal (GI) pathologies are common in older adults compared to young (≤40 years). Data on the diagnostic yield (DY) of colonoscopy with lower GI symptoms lacking. We aimed evaluate overall DY colonoscopy; and stratified by presence or absence bright red blood per rectum (BRBPR) ≤40 years. <b><i>Methods:</i></b> reviewed colonoscopies performed 18 gastroenterologists at 2 different institutions...
ABSTRACT Asparaginase is a part of combination chemotherapy for acute lymphoblastic leukemia. We present 58-year-old woman with refractory leukemia who developed asparaginase-induced hepatotoxicity after receiving intravenous PEG-L-asparaginase-based chemotherapy. The patient presented hyperbilirubinemia and transaminitis. was diagnosed drug-induced liver injury due to PEG-L-asparaginase thorough evaluation all other causes received treatment L-carnitine vitamin B complex normalization...