- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Venous Thromboembolism Diagnosis and Management
- Heart Failure Treatment and Management
- Cardiac Structural Anomalies and Repair
- Cardiac electrophysiology and arrhythmias
- Infectious Aortic and Vascular Conditions
- Cardiac Valve Diseases and Treatments
- Cardiac Arrest and Resuscitation
- Vascular Procedures and Complications
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Function and Risk Factors
- Cardiac and Coronary Surgery Techniques
- Body Composition Measurement Techniques
- Lipoproteins and Cardiovascular Health
- Mechanical Circulatory Support Devices
- Advanced Glycation End Products research
- Coronary Artery Anomalies
- Protease and Inhibitor Mechanisms
- Chronic Kidney Disease and Diabetes
Pusan National University Hospital
2014-2024
Christie's
2016
Pusan National University
2013-2014
Background: Treatment of critical limb ischemia (CLI) by bypass operation or percutaneous vascular intervention is occasionally difficult. The safety and efficacy multiple intramuscular adipose tissue-derived mesenchymal stem cells (ATMSC) injections in CLI patients was determined the study. Methods Results: study included 15 male with ischemic resting pain 1 with/without non-healing ulcers necrotic foot. ATMSC were isolated from tissue thromboangiitis obliterans (TAO) (B-ATMSC), diabetes...
<h3>Abstract</h3> A ubiquitous finding in cognitive science across a wide variety of tasks is that humans tend to slow down after making an error. The dominant account this post error slowing people engage adaptive control and are simply more cautious However, explanation challenged by the fact that, although slower, accuracy typically does not improve following Errors negatively impact processing, but characterizing nature error-based impairments has been challenge standard paradigms. Here,...
To evaluate the utility of cardiovascular magnetic resonance (CMR)-derived myocardial strain measurement for prediction poor outcomes in patients with acute myocarditis.We retrospectively analyzed data from 37 myocarditis who underwent CMR. Left ventricular (LV) size, LV mass index, ejection fraction and presence late gadolinium enhancement (LGE) were analyzed. circumferential (EccSAX), radial (ErrSAX) mid-ventricular level short-axis cine views longitudinal (EllLV), (ErrLax) measurements...
Adipose-derived stem cells (ADSCs) are known to be potentially effective in regeneration of damaged tissue. We aimed assess the effectiveness intracoronary administration ADSCs reducing infarction area and improving function after acute transmural myocardial (MI) a porcine model.ADSCs were obtained from each pig's abdominal subcutaneous fat tissue by simple liposuction. After 3 passages 14-days culture, 2 million injected into coronary artery 30 min MI. At baseline 4 weeks ADSC injection,...
Background/Aims Chronic thromboembolic pulmonary hypertension (CTEPH) is a life-threatening complication after acute embolism (APE) and associated with substantial morbidity mortality. This study aimed to investigate the incidence of CTEPH APE in Korea determine echocardiographic predictors CTEPH. Methods Among 381 patients confirmed by chest computed tomography (CT) between January 2007 July 2013, 246 consecutive available data were enrolled this study. was defined as persistent right...
Accurate volume measurement is important in the management of patients with congestive heart failure or renal insufficiency. A bioimpedance analyser can estimate total body water litres and has been widely used clinical practice due to its non-invasiveness ease results interpretation. To change impedance data volumetric data, analysers use equations derived from healthy subjects, which may not apply other conditions. Bioelectrical vector analysis (BIVA) was developed overcome dependence on...
Abstract The risk of malnutrition in acute kidney injury and mortality coronary artery disease patients has not been studied. This study aimed to evaluate whether nutritional status assessed by Onodera’s prognostic index (PNI) was related percutaneous intervention (PCI) outcomes. A total 3731 who received PCI between January 2010 December 2018 were included. relationship PNI at the time occurrence contrast-associated (AKI) all-cause death evaluated using logistic regression Cox proportional...
Background Diabetic cardiomyopathy (DM CMP) is defined as cardiomyocyte damage and ventricular dysfunction directly associated with diabetes independent of concomitant coronary artery disease or hypertension. Matrix metalloproteinases (MMPs), especially MMP-2, have been reported to underlie the pathogenesis DM CMP by increasing extracellular collagen content. Purpose We hypothesized that two discrete MMP-2 isoforms (full length FL-MMP-2; N-terminal truncated NTT-MMP-2) are induced high...
Statins remain the mainstay of secondary coronary artery disease (CAD) prevention, but n-3 polyunsaturated fatty acids (ω-3 PUFA) display biological effects that may also reduce risk atherosclerosis and CAD. However, data on possible antiatherosclerotic benefits adding ω-3 PUFA to statin therapy are limited. This study aimed investigate potential additive regression in CAD patients receiving stent implantation. Seventy-four undergoing percutaneous intervention (PCI) with implantation were...
BACKGROUND We evaluated the impact of normal vs. high presenting blood pressure (BP) on clinical outcomes and cardiac function in patients with ST-elevation myocardial infarction (MI). METHODS In 11,292 patients, in-hospital mortality major adverse events (MACE; all-cause death, nonfatal MI, or any revascularization) during follow-up were compared between (≥100mm Hg ≤139mm Hg) (≥140mm systolic BP at presentation. RESULTS Compared to BP, had significantly higher (1.5% 3.7%; P &lt; 0.001),...
Purpose: Thiazolidinediones are insulin-sensitizing agents that reduce neointimal proliferation and the adverse clinical outcomes associated with percutaneous coronary intervention (PCI) in patients diabetes mellitus (DM).There is little data on whether or not low dose pioglitazone reduces outcomes.Materials Methods: The study population included 121 DM artery disease they were randomly assigned to 60 taking 15 mg of daily addition their diabetic medications 61 placebo after index procedure...
Abstract Introduction Risk factors of embolic stroke (ES) after atrial fibrillation (AF) ablation have not been fully elucidated especially among the Asian subjects, particularly regarding epicardial adipose tissue (EAT) in cardiac imaging. We aimed to assess incidence ES during a long‐term follow‐up period AF and identify risk associated with postablation ES, specifically focusing on EAT. Methods Results enrolled patients who experienced control subjects from consortium registries three...
Primary percutaneous coronary intervention (PCI) is recommended for ST-segment elevation myocardial infarction (STEMI) patients even when the patient must be transported to a PCI-capable hospital. This study aimed evaluate long-term clinical outcomes of STEMI who were transferred primary PCI compared arrived directly hospitals.A total 3,576 with less than 12 h symptom onset-to-door time from Korea Acute Myocardial Infarction Registry divided into transfer (n = 2,176) and direct-arrival...
Objectives Obesity is a well-known cardiovascular disease risk factor. We evaluated the relationship between waist–hip ratio (WHR), as surrogate marker of central obesity, and clinical outcomes in patients with non-ST-segment elevation myocardial infarctions (NSTEMIs) undergoing percutaneous coronary interventions (PCIs). Methods Between 2008 2010, NSTEMI who underwent PCI had available anthropometric data were divided into three groups according to their WHR tertile range. Clinical...
Coronary cameral fistula (CCF) is a rare anomaly, where communication exists between an epicardial coronary artery and cardiac chamber. Assessing the hemodynamic significance of crucial to make decision concerning management process. We present two cases CCF, draining into left ventricle, in which was assessed by fractional flow reserve.
We aimed to investigate if left ventricular electromechanical delay (LVEMD) prolongation predicts trastuzumab-induced cardiotoxicity (TIC) in breast cancer patients.LVEMD on serial echocardiograms could be an indicator of subclinical TIC.We included 237 patients receiving trastuzumab chemotherapy, who underwent echocardiography at baseline and 6 12 months after initiation. LVEMD was defined as the time from electrical activation myocardial contraction. TIC ejection fraction (LVEF) worsening...
Background: We investigated the effect of nicorandil on infarct size, cardiac function assessed by magnetic resonance imaging (CMR) and outcomes in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI). Methods: In a prospective, randomised, controlled trial, 83 with STEMI receiving PCI were randomised into (n = 40) or placebo 43) groups. Nicorandil was administered emergency room before as an intravenous bolus 4 mg followed...
We evaluated whether prior statin therapy reduces in-hospital ventricular tachycardia/ventricular fibrillation (VT/VF) in percutaneous coronary intervention (PCI) patients with acute myocardial infarction (MI). Among the 1177 from Acute Myocardial Infarction Registry-National Institutes of Health (KAMIR-NIH), 823 (70%) received therapy. Prior was associated a reduced risk VT/VF events both adjusted propensity score analysis (odds ratio [OR] 0.414, 95% confidence interval [CI], 0.198-0.865, P...