A5020514601- Antimicrobial agents and applications
- Coronary Interventions and Diagnostics
- Occupational exposure and asthma
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Air Quality and Health Impacts
- Acute Myocardial Infarction Research
- Counseling Practices and Supervision
- Cardiac Imaging and Diagnostics
- Psychosocial Factors Impacting Youth
- Environmental Chemistry and Analysis
- Occupational and environmental lung diseases
- Biopolymer Synthesis and Applications
- Primate Behavior and Ecology
- biodegradable polymer synthesis and properties
- Nanoparticles: synthesis and applications
- IL-33, ST2, and ILC Pathways
- Animal testing and alternatives
- Indoor Air Quality and Microbial Exposure
- Biomarkers in Disease Mechanisms
- Immune Cell Function and Interaction
- Heart Failure Treatment and Management
- Veterinary Pharmacology and Anesthesia
- Inflammasome and immune disorders
- T-cell and B-cell Immunology
- Dermatology and Skin Diseases
Korea Institute of Toxicology
2014-2025
Children's Hospital of Fudan University
2019-2022
Korea Research Institute of Chemical Technology
2008-2021
Pusan National University Hospital
2013-2018
National Youth Policy Institute
2017
Busan Medical Center
2009-2014
Pusan National University
2011-2014
Abstract Background Invasive fungal disease (IFD) is a common complication observed in inborn errors of immunodeficiency (IEI) patients, and little known about the overall prevalence IFD IEI patients. We aimed to summarize spectrum outcomes IFDs Chinese cohort hospitalized patients with IEI. Methods In this retrospective study, 607 from January 2018 June 2022 were included. Demographic, clinical, infection data patient characteristics collected analyzed according classification. Results One...
Nonhuman primates are increasingly used in biomedical research since they highly homologous to humans compared other rodent animals. However, there is limited reliable reference data of the clinical pathology parameters cynomolgus monkeys, and particular, only some coagulation urinalysis have been reported. Here, we reported chemical, hematological, blood coagulation, monkeys. The role sex differences was analyzed several (including hematocrit, hemoglobin, red cell, urea nitrogen, total...
Insufficient exploration of multicultural social justice competence in research methodology and procedures may contribute to lingering clinical problems for diverse populations. Using transcultural theory evaluate the effectiveness cross‐national research, authors examined various methodological challenges during design, analysis, interpretation stages. Recommendations focus on expanding Multicultural Social Justice Counseling Competencies (Ratts, Singh, Nassar‐McMillan, Butler, &...
Abstract This year, France banned the application of titanium dioxide nanoparticles as a food additive (hereafter, E171) based on insufficient oral toxicity data. Here, we investigated subchronic toxic responses E171 (0, 10, 100, and 1,000 mg/kg) tried to elucidate possible mechanism using AGS cells, human stomach epithelial cell line. There were no dose‐related changes in Organisation for Economic Cooperation Development test guideline‐related endpoints. Meanwhile, deeply penetrated cells...
Exposure to diesel exhaust particles (DEPs) is inevitable and closely linked with increased health hazards, causing pulmonary abnormalities by increasing inflammation, hypoxia, so on. Moreover, long-term exposure DEPs may trigger whole-body toxicity behavioral alterations. Therefore, nutritional intervention natural components be desirable prevent and/or ameliorate DEP-inducible pathophysiology in mammals. Quercetin has been demonstrated reduce metabolic complications possessing...
Polyhexamethylene guanidine phosphate (PHMG-P), a cationic biocide, is widely used in household products due to its strong bactericidal activity and low toxicity. However, it causes fatal lung damage when inhaled. In this study, we investigated why PHMG-P injury inhaled, demonstrated that the disruption of membrane integrity through ionic interaction-a molecular initiating event PHMG-P-determines Mice were injected intravenously with 0.9 or 7.2 mg/kg (IV group), instilled intratracheally...
Many ST-segment elevation myocardial infarction (STEMI) patients have multivessel disease. There is still controversy in treatment strategy STEMI with We compared clinical outcomes of revascularization infarct- related artery (IRA) patients.The 1,644 disease (1,106 IRA group, 538 group) who were received primary percutaneous coronary intervention (PCI) analyzed from a nationwide Korea Acute Myocardial Infarction Registry. Primary endpoint was 12-month major adverse cardiac events (MACE,...
As chronic exposure to welding fumes causes pulmonary diseases, such as pneumoconiosis, public concern has increased regarding continued these hazardous gases in the workplace. In a previous study, inflammatory response fume was analysed rat lungs case of recurrent and recovery periods. Thus using lung samples, well-annotated by histological observation biochemical analysis, this study examines gene expression profiles identify phenotype-anchored genes corresponding inflammation repair...
Repeated exposure to welding fumes promotes a reversible increase in pulmonary disease risk, but the molecular mechanisms by which induce lung injury and how recovers from such insults are unclear. In present study, function gene-expression profiles were analyzed Affymetrix GeneChip microarray after 30 days of consecutive manual metal arc combined with stainless-steel (MMA-SS) fumes, again recovery MMA-SS fume exposure. total, 577 genes identified as being either up-regulated or...
The number of individuals with underlying medical conditions has been increasing steadily. These are relatively vulnerable to harmful external factors. But it not proven that the effects hazardous chemicals may differ depending on their physicochemical properties. This study determines toxic two high indoor exposure risk and different properties an disease model. A pulmonary arterial hypertension (PAH) model was constructed by a single subcutaneous injection monocrotaline (MCT; 60 mg/kg)...
Purpose: Thiazolidinediones are insulin-sensitizing agents that reduce neointimal proliferation and the adverse clinical outcomes associated with percutaneous coronary intervention (PCI) in patients diabetes mellitus (DM).There is little data on whether or not low dose pioglitazone reduces outcomes.Materials Methods: The study population included 121 DM artery disease they were randomly assigned to 60 taking 15 mg of daily addition their diabetic medications 61 placebo after index procedure...