- Constructed Wetlands for Wastewater Treatment
- Coastal wetland ecosystem dynamics
- Plant Stress Responses and Tolerance
- Antibiotic Resistance in Bacteria
- Plant responses to water stress
- Wastewater Treatment and Nitrogen Removal
- Antibiotics Pharmacokinetics and Efficacy
- Biocrusts and Microbial Ecology
- Power System Reliability and Maintenance
- Energy Load and Power Forecasting
- Machine Fault Diagnosis Techniques
- Chromium effects and bioremediation
- Bacterial biofilms and quorum sensing
- Remote Sensing in Agriculture
- Plant Micronutrient Interactions and Effects
- Signaling Pathways in Disease
- Berberine and alkaloids research
- Total Knee Arthroplasty Outcomes
- Legume Nitrogen Fixing Symbiosis
- Antimicrobial Resistance in Staphylococcus
- Aquatic Ecosystems and Phytoplankton Dynamics
- Heavy metals in environment
- Immune Response and Inflammation
- Nephrotoxicity and Medicinal Plants
- Intravenous Infusion Technology and Safety
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2025
Harbin Medical University
2022-2024
Second Affiliated Hospital of Harbin Medical University
2024
Jinan University
2024
First Affiliated Hospital of Harbin Medical University
2022
Changhai Hospital
2022
Second Military Medical University
2022
Zhejiang Chinese Medical University
2021-2022
North China Electric Power University
2021
Shenyang Pharmaceutical University
2018-2020
Abstract Doxorubicin (DOX) is an effective anticancer agent, but its clinical utility constrained by dose‐dependent cardiotoxicity, partly due to cardiomyocyte ferroptosis. However, the progress of developing cardioprotective medications counteract ferroptosis has encountered obstacles. Protosappanin A (PrA), anti‐inflammatory compound derived from hematoxylin, shows potential against DOX‐induced cardiomyopathy (DIC). Here, it reported that PrA alleviates myocardial damage and dysfunction...
Abstract The plants effect in subsurface flow constructed wetlands (SSF-CWs) is controversial, especially at low temperatures. Consequently, several SSF-CWs planted with Iris pseudacorus (CW I ) or Typha orientalis Presl. T and unplanted ones C were set up fed secondary effluent of sewage treatment plant during the winter Eastern China. 16S rDNA Illumina Miseq sequencing analysis indicated positive effects . on bacterial community richness diversity substrate. Moreover, compositions bacteria...
Methicillin-resistant Staphylococcus aureus (MRSA) infection is a serious clinical threat, and D-Serine (D-Ser) showed significant sensitization effects on β-lactams against MRSA in our previous study. Quantitative PCR analysis found the elevated expression of dlt operon with D-Ser combination, which responsible for wall teichoic acid (WTA) modification involving D-Alanine (D-Ala). This study aims to verify effect WTA through pathway explore related bacteria. The DltA DltC were recombined,...
Haemophilic arthropathy (HA), a common complication of haemophilia, is secondary to recurrent joint bleeding and increases the prevalence end-stage osteoarthritis (OA). Total knee arthroplasty (TKA) reliable treatment for haemophilia patients. This study was performed evaluate mid-term outcomes TKA HA. We hypothesized that rate complications higher patients with than without haemophilia.Patients HA undergoing from January 2015 December 2016 in our centre were retrospectively reviewed. All...
Polymyxin B and polymyxin E (colistin) are presently considered the last line of defense against human infections caused by multidrug-resistant Gram-negative organisms such as carbapenemase-producer Enterobacterales, Acinetobacter baumannii, Klebsiella pneumoniae. Yet resistance to this last-line drugs is a major public health threat rapidly increasing. S2 (S2) analogue previously synthesized in our institute with obviously high antibacterial activity lower toxicity than colistin. To predict...
The decline of submerged plants resulting from low light and high ammonia nitrogen (ammonia-N) has become a serious problem worldwide. In the present study, three levels ammonia-N concentrations (0, 3 6mgL–1) four intensity (control, 15, 2.5 0.75% underwater light) were designed to investigate combined effects stress on plant Vallisneria natans. examined by measuring relative growth rate (RGR), chlorophyll content superoxide dismutase (SOD) peroxidase (POD) activity in response stressors....
To investigate the role and microorganism-related mechanisms of macrophytes assess feasibility Oenanthe javanica (Blume) DC. in promoting nitrogen removal free-water surface constructed wetlands (FWS-CWS) under low temperatures (<10 °C), pilot-scale FWS-CWS, planted with O. javanica, were set up run for batch wastewater treatment eastern China during winter. The presence observably improved rates ammonia (65%–71%) total (41%–48%) (p < 0.05), a sharp increase chemical oxygen demand...
Background. The decline of submerged plant populations due to high heavy metal (e.g., Cu) levels in sediments and ammonia nitrogen (ammonia-N) accumulation the freshwater column has become a significant global problem. Previous studies have evaluated effect ammonia-N on macrophytes, but few focused influence sediment Cu macrophytes their combined effects. Methods. In this paper, we selected three (0, 3, 6 mg L −1 ) (25.75 ± 6.02 as control, 125.75 6.02, 225.75 kg ), investigate Vallisneria...
Constructed floating wetlands (CFWs) are used to treat waste waters of various origins either alone or as part water treatment trains. The aim the present study was determine extent nitrogen removal by CFWs planted with Oenanthe javanica (Blume) DC. at low temperatures (<10°C) and whether vesuvianite a substrate perform better than those without substrate. A batch model used, O. (Tc), (Ts), (Tp) mats only (To) control. average rates NH4+-N, NO3–-N total were 78.3, 44.4 49.7% respectively...
To identify the facilitation effect of a cool-season aquatic macrophyte (FEam) for use in effluent purification via constructed floating wetlands (CFWs) and to determine possible pathways used during winter period with an average temperature less than 5 °C, pilot-scale CFWs were planted cold-season Oenanthe clecumbens operated as batch systems. Although some leaves withered, roots retained relatively high levels activity winter, which had air water temperatures 3.63 5.04 respectively. The N...
Abstract Background Infections caused by drug-resistant Staphylococcus aureus , especially vancomycin-intermediate (VISA), leave clinicians with limited therapeutic options for treatment. Persister cells is a leading cause of recalcitrant infection and antibiotic treatment failure, there no drug in clinical use that specifically targets persister currently. Here, we report promising combination therapy sodium new houttuyfonate (SNH) berberine chloride (BBR) which able to eradicate both...
Sepsis has become a global health concern owing to its increasing incidence and high mortality rate. In the present study, we investigated novel drug candidate ASK0912 on protective effects in mice with Acinetobacter baumannii 20-1-induced sepsis, studied related mechanisms.To analyze effect of septic mice, survival rates, body temperature, organ blood bacterial loads, white cell platelet counts, damage, cytokine levels were determined.ASK0912 remarkably increased rate sepsis induced by A....
Rheumatoid arthritis (RA) is a chronic, systemic autoimmune inflammatory disorder. Diet recognized as modifiable factor that may influence inflammation and potentially accelerate RA progression. Nevertheless, the effects of diverse dietary patterns their combined impact on progression long-term mortality remain inadequately understood. This study examined association between in patients with RA, focusing Healthy Eating Index (HEI-2015) Dietary Inflammatory (DII) evaluating effects. The...
Numerous studies have demonstrated the feasibility of remotely sensing water clarity lakes, reservoirs, and larger rivers using medium-resolution spatial images. However, addressing relatively small or river sections is very challenging due to adjacency effect from riverbanks. The objectives this study are quantify minimum width for quality remote validate images estimating Secchi disk depth (SDD). A methodology was developed high-resolution WorldView-2 Pléiades. Our results suggest that...
The ability to maintain redox homeostasis is critical for Mycobacterium tuberculosis (Mtb) survive the stress of host. There are many antioxidant systems in Mtb ensure its normal replication and survival host, cysteine thiols one them. S-sulfenylation reversible modifications resist oxidative stress. In study, we investigated total modification proteome under provided by hydrogen peroxide. To determine quantify modified proteins, high specific IodoTMT6plex reagents resolution mass...