A5020916543- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Fetal and Pediatric Neurological Disorders
- Functional Brain Connectivity Studies
- Muscle activation and electromyography studies
- Cerebrovascular and Carotid Artery Diseases
- Sports injuries and prevention
- Neonatal and fetal brain pathology
- Traumatic Brain Injury and Neurovascular Disturbances
- Neural dynamics and brain function
- Nanoparticle-Based Drug Delivery
- Sports Performance and Training
- Migraine and Headache Studies
- MRI in cancer diagnosis
- Lower Extremity Biomechanics and Pathologies
- Face Recognition and Perception
- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Lanthanide and Transition Metal Complexes
- Acute Ischemic Stroke Management
- Transplantation: Methods and Outcomes
Semmelweis University
2016-2025
Introduction: One of the major challenges in clinical translation nanoparticles is development formulations combining favorable efficacy and optimal safety. In past, iron oxide have been introduced as an alternative for gadolinium-containing contrast agents; however, candidates available at time were not free from adverse effects. Methods: Following a potent oxide-based agent SPION Dex , we now performed systematic comparison this formulation with conventional ferucarbotran ferumoxytol,...
To test utility of diffusion MRI-derived indices in carotid endarterectomy (CEA), change tensor imaging (DTI) metrics, cerebral white matter (WM) volumes were evaluated and predictors overall mortality determined. Prospectively enrolled participants had preoperative, immediate late postoperative DTI after CEA. WM volumes, metrics (fractional anisotropy, FA; axial, radial, mean diffusivities; AD, RD, MD, respectively) calculated for the index/contralateral hemispheres at all time points....
Abstract Background Schizophrenia (SZ) is a complex disorder characterized by range of behavioral and cognitive symptoms as well structural functional alterations in multiple cortical subcortical structures. SZ associated with reduced network connectivity involving core regions such the anterior cingulate cortex (ACC) thalamus. However, little known whether effective coupling, directed influence one structure over other, altered during rest ACC–thalamus network. Methods We collected...
Abstract Background Identification of early signs hypoxic ischemic encephalopathy (HIE) with magnetic resonance imaging (MRI) has proven prognostic significance. Yet, the importance intracranial hemorrhage (ICH), being present concomitantly had not been investigated yet, despite known influence hypothermia on hemostasis. We aimed to determine whether presence ICH MRI alongside HIE have an impact prognosis in neonates clinical diagnosis HIE. Methods A retrospective study consecutively sampled...
Abstract Aim To assess the long‐term neurodevelopmental outcome of neonates born at term diagnosed with perinatal haemorrhagic stroke (PHS) and investigate associations among brain territorial involvement, clinical risk factors, outcomes. Method We conducted a population‐based study enrolling 55 PHS confirmed by magnetic resonance imaging between 2007 2017. Long‐term was assessed using Bayley Scales Infant Development, Second Edition, Brunet–Lézine test, Stanford–Binet Intelligence Scales,...
Background Diffusion-tensor imaging can be applied to describe the microstructural integrity of whole brain. As findings about alterations in migraine are inconsistent, we aimed replicate most frequent results and assess a relationship between parameters changes microstructure. Methods Diffusion-weighted MRI data 37 patients 40 controls were collected. Two indices diffusion water molecules, fractional anisotropy mean diffusivity used voxel-wise analysis. Group comparisons carried out SPM12...
Quantitative MRI methods have recently gained extensive interest and are seeing substantial developments; however, their application in single patient vs control group comparisons is often limited by inherent statistical difficulties. One such detecting malformations of cortical development (MCDs) behind drug resistant epilepsies, a task that, especially when based solely on conventional MR images, may represent serious challenge. We aimed to develop novel straightforward voxel-wise...
describing the changes of modularity in different clinical states can help to understand alterations global processing mechanisms. In current study we applied a local scale. The method is based on measuring decrease caused by shifting node from its own module another module. On one hand measures influence formation modular organization. other evaluated differences community membership nodes between structures two groups. was tested resting-state fMRI data 20 young and elderly subjects....
Abstract Purpose We assessed diffusion tensor imaging (DTI) metric changes of the corpus callosum and cingulum correlated to postprocedural ischemic lesion load (ILL) cognitive performance in transcatheter aortic valve replacement (TAVR). Methods TAVR subjects had DTI post-TAVR (≤ 8 days) at 6 months (78 participants, males 56%, age 78.8 years ± 6.3) four neurocognitive tests (pre-TAVR, post-TAVR, months, 1 year). metrics (fractional anisotropy (FA), mean diffusivity (MD), axial (AD), radial...
Háttér és cél – Az MRI First! projekt keretén belül 2020. január 1-jétől ictalis neurológiai góctünettel jelentkező betegek esetében elsődleges modalitásként MRI-vizsgálatot végzünk. Célunk a klinikai tüneteket magyarázó eltérések kimutatása, további potenciális kezeléshez minél pontosabb adatok közlése parenchyma állapotáról, perfúziós vascularis viszonyokról. Módszerek A vizsgálatokat 1,5 Tesla Philips Ingenia MR-készüléken végeztük. Vizsgálati protokollként koponyáról axialis FLAIR, DWI...