Alessandro Giovinazzo

ORCID: 0000-0003-4420-6257
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About
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Research Areas
  • DNA Repair Mechanisms
  • Microfluidic and Bio-sensing Technologies
  • Cancer-related Molecular Pathways
  • Genomics and Phylogenetic Studies
  • SARS-CoV-2 and COVID-19 Research
  • Chromosomal and Genetic Variations
  • Mitochondrial Function and Pathology
  • COVID-19 Clinical Research Studies
  • Immune cells in cancer
  • Signaling Pathways in Disease
  • Acute Myeloid Leukemia Research
  • CRISPR and Genetic Engineering
  • Diabetes and associated disorders
  • Hematopoietic Stem Cell Transplantation
  • Phagocytosis and Immune Regulation
  • 3D Printing in Biomedical Research
  • Tryptophan and brain disorders
  • Toxin Mechanisms and Immunotoxins
  • Immune Cell Function and Interaction
  • Galectins and Cancer Biology
  • Electrical and Bioimpedance Tomography

Institute of Cell Biology and Neurobiology
2021-2024

University of Rome Tor Vergata
2018-2023

Coronavirus disease 2019 (COVID-19) is characterized by immune-mediated lung injury and complex alterations of the immune system, such as lymphopenia cytokine storm, that have been associated with adverse outcomes underlining a fundamental role host response in severe acute respiratory syndrome coronavirus 2 infection pathogenesis disease. Thymosin alpha 1 (Tα1) one molecules used management COVID-19, because it known to restore homeostasis system during infections cancer.In this study, we...

10.1093/ofid/ofaa588 article EN cc-by-nc-nd Open Forum Infectious Diseases 2020-12-05

Background: Thymosin alpha 1 (Tα1) is a well-recognized immune response modulator in wide range of disorders, particularly infections and cancer. The bioinformatic analysis public databases allows drug repositioning, predicting new potential area clinical intervention. We aimed to decipher the cellular network induced by Tα1 treatment confirm present use identify applications.Research design methods: used transcriptional profile human peripheral blood mononuclear cells treated vitro with...

10.1080/14712598.2018.1474198 article EN Expert Opinion on Biological Therapy 2018-05-31
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