A5013583550- Palliative Care and End-of-Life Issues
- Cancer survivorship and care
- Family Support in Illness
- Childhood Cancer Survivors' Quality of Life
- Multiple Myeloma Research and Treatments
- Hepatitis C virus research
- Inflammatory Bowel Disease
- Healthcare professionals’ stress and burnout
- Peptidase Inhibition and Analysis
- Protein Degradation and Inhibitors
- Microscopic Colitis
- Neuroinflammation and Neurodegeneration Mechanisms
- Alzheimer's disease research and treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Spondyloarthritis Studies and Treatments
- Global and Cross-Cultural Management
- Viral Infections and Immunology Research
- Music Therapy and Health
- Optimism, Hope, and Well-being
- Systemic Lupus Erythematosus Research
- Business, Innovation, and Economy
- Multiple Sclerosis Research Studies
- Diverse Applied Research Studies
- Protein Interaction Studies and Fluorescence Analysis
- Obsessive-Compulsive Spectrum Disorders
Columbia University
2024
Columbia University Irving Medical Center
2024
The University of Texas MD Anderson Cancer Center
2016-2023
University of Puerto Rico System
2020
Santa Lucía University General Hospital
2013-2016
Hospital General Universitario Santa María del Rosell
2008
Abstract INTRODUCTION Evidence suggests microglial activation precedes regional tau and neurodegeneration in Alzheimer's disease (AD). We characterized microglia with translocator protein (TSPO) positron emission tomography (PET) within an AD progression model where global amyloid beta (Aβ) local neurodegeneration, resulting cognitive impairment. METHODS Florbetaben, PBR28, MK‐6240 PET, T1 magnetic resonance imaging, measures were performed 19 cognitively unimpaired older adults 22 patients...
Abstract Context : Palliative care encompasses an interdisciplinary team, including mental health professionals, to address psychological distress of cancer patients. Objectives To present the implementation outreach counseling program via videoconferencing or telephone patients receiving in outpatient palliative clinic and compare using this service those who only received our clinic. Methods We conducted a retrospective chart review seen for psychology services supportive center between...
Abstract Objectives Microglia monitor and respond to the brain ’ s microenvironment maintain homeostasis. However, in Alzheimer disease related dementias (ADRD), microglia may contribute pathology. We hypothesized that AD-related inflammatory changes, measured with TSPO PET, would be locally associated amyloid, tau, neurodegeneration, influence key pathways among them. Methods Participants (21 controls, 25 ADRD) from Longitudinal Imaging of Microglial Activation Different Clinical Variants...
Young adult (YA) aged cancer patients have unique psychosocial needs with studies indicating more symptoms and emotional distress compared to older patients. Our study aimed compare clinical characteristics symptom between YAs adults. We retrospectively studied 896 randomly selected across 3 age groups: 18–39 (n = 297), 40–64 300), 65 299). medical, history, Morphine Equivalent Daily Dose (MEDD), Edmonton Symptom Assessment Scale (ESAS) scores, Eastern Cooperative Oncology Group (ECOG)...
Describir el uso de bortezomib en un hospital comarcal como alternativa tratamiento gammapatías malignas. Análisis retrospectivo los pacientes tratados con nuestro desde noviembre 2005 hasta octubre 2007. A partir la revisión las historias clínicas se recogieron datos correspondientes al diagnóstico, tratamientos previos a bortezomib, fecha última progresión enfermedad, número ciclos respuesta éste, supervivencia global y libre progresión, complicaciones efectos secundarios. El 47%...
<h3>Background</h3> The use of drugs during pregnancy is always controversial. There limited information about the infliximab pregnancy. <h3>Purpose</h3> To describe effectiveness and safety in a patient with ankylosing spondylitis <h3>Material methods</h3> Retrospective observational study pregnant woman who was treated infliximab. data collected was: week gestation, dosage laboratory data: erythrocyte sedimentation rate (ESR) C-reactive protein (CRP). <h3>Results</h3> A 32-year-old...
Pediatric brain tumor survivors have an increased risk of psychological distress. They exhibit more symptoms depression, somatization, fatigue, and daytime sleepiness than their siblings.1 Severe distress is profoundly disabling, but the prevalence factors for specific mental disorders after treatment in pediatric patients with tumors unknown. The following case study sudden-onset obsessive-compulsive disorder (OCD) optic pathway glioma highlights this gap understanding.
<h3>Background</h3> Behçet's disease (BD) is a rheumatic characterised by polyarthritis, urogenital ulcers, uveitis, cutaneous lesions, alterations in the central nervous system and vascular disease. <h3>Purpose</h3> To describe use of adalimumab patient with BD whom immunosuppressant treatment had failed. <h3>Material methods</h3> Follow-up treated after trying other treatments without success. The most common parameters used when monitoring are: erythrocyte sedimentation rate (ESR)...
<h3>Background</h3> Since 1981, the year of first case infection with HIV/AIDS, about 60 million people have been infected virus, and some 20 died. But since appearance in 1995 so-called highly active antiretroviral therapy, there dramatic reductions observed morbidity mortality rates. <h3>Purpose</h3> To evaluate use elvitegravir/cobicistat/emtricitabine/tenofovir (EVG/COBI/FTC/TDF) patients HIV to check adequacy prescription, as indicated by Therapy Group regional Pharmacy Therapeutics...
<h3>Background</h3> Oncology patients are susceptible to malnutrition and this is a risk factor for morbidity mortality. <h3>Purpose</h3> To evaluate nutritional status in treated with oral chemotherapy tertiary hospital. <h3>Material methods</h3> Preliminary study including all antineoplastic drugs cited the outpatient pharmaceutical care consultation during May 2015. Patients less than 3 months were excluded. The variables collected were: age, sex, neoplasia, drug used, height, current...
<h3>Background</h3> Idiopathic thrombocytopenic purpura (ITP) is a disease characterised by decreased platelet count. Romiplostim and eltrombopag are thrombopoietin receptor agonists (TRAs) that stimulate production. <h3>Purpose</h3> To evaluate the effectiveness safety of TRAs in patients with ITP university hospital. <h3>Material methods</h3> Retrospective observational study including who were treated TRAs. The information collected was: age, gender, previous treatments, length treatment,...
230 Background: Despite high distress, a small percentage of cancer patients are referred for psychological care. MD Anderson’s interdisciplinary Palliative Care team recruited 2 clinical psychologists in 9/2013. The demand services exceeded capacity; thus 3rd psychologist and 3 counselors were added 6/2015. Methods: Retrospective review 2827 unique (6451 total contacts) from 9/1/2013 to 2/29/2016, including billable (psychologists) non-billable (counselors) services. Results: Psychologists...
Durante los últimos años, se han realizado grandes esfuerzos por mejorar la situación de niños, niñas y adolescentes. Si revisa el texto Ley Orgánica para Protección Niños, Niñas Adolescentes, evidencia en instrumento jurídico, que no establece sanciones funcionarios policiales denegación justicia adolescentes marco las garantías constitucionales debe recurrir a lo al respecto ha establecido Código Procedimiento Civil, donde, allí preceptuadas son pecuniarias. Desde esta perspectiva eleva...
<h3>Background</h3> Anti-TNF drugs show high inter-individual variability in efficacy and toxicity. Currently there are no genetic, biochemical or environmental markers to predict response treatment. <h3>Purpose</h3> To assess the influence of gene polymorphism rs2230229 TRAILR1 as a genetic marker treatment with infliximab patients diagnosed Crohn’s disease (CD). Will it enable us improve effectiveness drug? <h3>Materials Methods</h3> Prospective observational study all CD treated at our...
284 Background: Patients with cancer are considered a highly vulnerable group, especially during the COVID-19 pandemic. There is limited literature describing level of spiritual distress COVID pandemic and its association physical psychological in this population. Methods: Retrospective chart review 1264 patients seen by Outpatient Palliative Care Team from May 1st, 2020 to December 31st, (during COVID-19), 85% consults was delivered Telemedicine. The ESAS-FS symptoms, Spiritual Pain (SP),...
184 Background: MD Anderson’s interdisciplinary out-patient clinic, palliative care team includes mental health professionals who provide psychological care, including 3 full time Master’s level counselors. Counseling sessions are offered during the patient’s clinic appointments. To increase opportunity and access for additional counseling, patients follow-up counseling through an outreach program which videoconferencing or telephone sessions. The data presented represents almost 2 years of...
183 Background: From Jan 2013 to Dec 2015, only 23% of inpatient palliative care consults were referred for psychology (PSY) services. In an effort better understand referral practices, we compared those who PSY services not. Methods: A retrospective chart review 930 consecutive patients from 2015 was conducted collect demographic and clinical variables. 455 had at least one contact 475 no randomly selected. control age, selected 330 18-39 years, 300 40-64 65 older. Descriptive, univariate...
168 Background: Literature suggests that YA cancer patients have unique psychosocial issues and more emotional distress compared to older aged patients. Our study aimed evaluate clinical demographic factors of may impact physical symptom expression. Methods: A retrospective review was conducted on randomly selected seen during 2013-2015 3 age groups: 18-39 (YA), 40-64, 65 demographic, medical, history, Morphine Equivalent Daily Dose (MEDD), Edmonton Symptom Assessment Scare (ESAS) scores,...
La presente investigacion trato sobre el diagnostico turistico de la oferta pequenas empresas en parroquia Belisario Quevedo. metodologia utilizada permitio diagnosticar y caracterizar oferta, demanda asi como comunidad que se desarrollan, utilizacion los metodos: descriptivo campo, deductivo conocer realidad las empresas, mismas que encuentran lineas desarrollo, siendo un aporte para su fortalecimiento progreso, ya actualidad PYMES tienen rol importante turismo comunitario representan 40%...