A5046136400- Cancer survivorship and care
- Cancer-related molecular mechanisms research
- Complementary and Alternative Medicine Studies
- RNA modifications and cancer
- Organ Transplantation Techniques and Outcomes
- Transplantation: Methods and Outcomes
- Head and Neck Cancer Studies
- Acute Myeloid Leukemia Research
- Nitric Oxide and Endothelin Effects
- Molecular Biology Techniques and Applications
- Birth, Development, and Health
- RNA and protein synthesis mechanisms
- Neuropeptides and Animal Physiology
- Veterinary Oncology Research
- RNA Research and Splicing
- Gene expression and cancer classification
- RNA Interference and Gene Delivery
- Pregnancy and Medication Impact
- Chronic Lymphocytic Leukemia Research
- Circular RNAs in diseases
- Virus-based gene therapy research
- Cancer Genomics and Diagnostics
- Childhood Cancer Survivors' Quality of Life
- Acupuncture Treatment Research Studies
- Cancer-related cognitive impairment studies
Fujian Medical University
2019-2025
Wuhan University
2018-2025
China University of Petroleum, East China
2025
First Hospital of Lanzhou University
2025
Lanzhou University
2025
Nanjing University of Chinese Medicine
2025
Institute for Systems Biology
2023-2024
InSysBio (Russia)
2024
Anqing Normal University
2024
Southern Medical University
2014-2024
At least 75% of head and neck cancers are attributable to a combination cigarette smoking alcohol drinking. A precise understanding the independent association each these factors in absence other with risk cancer is needed elucidate mechanisms carcinogenesis assess efficacy interventions aimed at controlling either factor. We examined extent which associated among never drinkers drinking users tobacco. pooled individual-level data from 15 case–control studies that included 10244 case...
The epithelial-to-mesenchymal transition (EMT) is a cell development-regulated process in which noncoding RNAs act as crucial modulators. Recent studies have implied that EMT may contribute to resistance epidermal growth factor receptor (EGFR)-directed therapy. aims of this study were determine the potential role microRNAs (miRNA) controlling and inducing sensitivity human bladder cancer cells inhibitory effects anti-EGFR therapy.miRNA array screening real-time reverse transcription-PCR used...
Purpose Previous research incorporating yoga (YG) into radiotherapy (XRT) for women with breast cancer finds improved quality of life (QOL). However, shortcomings in this limit the findings. Patients and Methods stages 0 to III were recruited before starting XRT randomly assigned YG (n = 53) or stretching (ST; n 56) three times a week 6 weeks during waitlist (WL; 54) control. Self-report measures QOL (Medical Outcomes Study 36-item short-form survey; primary outcomes), fatigue, depression,...
Conclusions Our results support that cessation of tobacco smoking and alcohol drinking protect against the development head neck cancer.
Purpose Evidence has supported the association between psychological factors and cancer biology; however, findings are equivocal on role of psychosocial in progression. This study generates a hypothesis mechanistic variables by examining clinical effects cortisol dysregulation patients with metastatic renal cell carcinoma (RCC) examines associated activation transcription control pathways. Methods Patients RCC (n = 217) were prospectively enrolled this study. completed questionnaires...
Abstract BACKGROUND: Radiotherapy may lead to side effects that undermine patients' quality of life (QOL). Although mind‐body practices like qigong appear improve QOL in cancer survivors, little is known about their benefits for patients who are receiving radiotherapy. Thus, the current randomized controlled trial, authors examined efficacy a intervention on women with breast during and after treatment. METHODS: Ninety‐six were recruited from center Shanghai, China, group (N = 49) or...
BACKGROUND The current randomized trial examined the effects of a Tibetan yoga program (TYP) versus stretching (STP) and usual care (UC) on sleep fatigue in women with breast cancer who were undergoing chemotherapy. METHODS Women stage (American Joint Committee Cancer (AJCC) TNM) I to III chemotherapy TYP (74 women), STP (68 or UC (85 women). Participants groups participated 4 sessions during chemotherapy, followed by 3 booster over subsequent 6 months, encouraged practice at home....
ObjectiveTo clarify the relationship between use of extracorporeal life support during lung transplantation and severe primary graft dysfunction (PGD), we developed analyzed a novel multicenter international registry.MethodsThe Extracorporeal Life Support in Lung Transplantation Registry includes double-lung transplants performed at 8 high-volume centers (>40/year). Multiorgan were excluded. We defined PGD as grade 3 (PGD3) observed 48 or 72 hours after reperfusion. Modes no (off-pump),...
Abstract BACKGROUND: Xerostomia (dry mouth) after head/neck radiation is a common problem among cancer patients, and available treatments are of little benefit. The objective this trial was to determine whether acupuncture can prevent xerostomia patients undergoing radiotherapy. METHODS: A randomized, controlled with nasopharyngeal carcinoma conducted comparing standard care. Participants were treated at Fudan University Shanghai Cancer Center, Shanghai, China. Forty randomized treatment 46...
To assess whether stress management (SM) improved immune outcomes in men undergoing surgery for prostate cancer.A total of 159 were assigned randomly to a two-session presurgical SM intervention, supportive attention (SA) group, or standard care (SC) group. Men the group discussed their concerns about upcoming and taught diaphragmatic breathing, guided imagery; they had an imaginal exposure day learned adaptive coping skills. SA semistructured medical interview. Blood samples collected at...
<h3>Importance</h3> Radiation-induced xerostomia (RIX) is a common, often debilitating, adverse effect of radiation therapy among patients with head and neck cancer. Quality life can be severely affected, current treatments have limited benefit. <h3>Objective</h3> To determine if acupuncture prevent RIX in cancer undergoing therapy. <h3>Design, Setting, Participants</h3> This 2-center, phase 3, randomized clinical trial compared standard care control (SCC) true (TA) sham (SA) oropharyngeal...
In the context of immune-mediated inflammatory diseases (IMIDs), COVID-19 outcomes are incompletely understood and vary considerably depending on patient population studied. We aimed to analyse severe investigate effects pandemic time period risks associated with individual IMIDs, classes immunomodulatory medications (IMMs), chronic comorbidities, vaccination status.
Purpose This study assessed the short-term and long-term efficacy of a presurgical stress management intervention at reducing mood disturbance improving quality life (QOL) in men undergoing radical prostatectomy (RP) for prostate cancer. Patients Methods One hundred fifty-nine were randomly assigned to two-session (plus two boosters) (SM), supportive attention group (SA), or standard care (SC). Assessments occurred 1 month before surgery; week morning 6 weeks after surgery, 12 months...
Competitions in text mining have been used to measure the performance of automatic processing solutions against a manually annotated gold standard corpus (GSC). The preparation GSC is time-consuming and costly final consists at most few thousand documents with limited set semantic groups. To overcome these shortcomings, CALBC project partners (PPs) produced large-scale biomedical four different groups through harmonisation annotations from solutions, first version Silver Standard Corpus...
Background. In China, the use of traditional Chinese medicine (TCM) is very popular, but little known about how it integrated with conventional cancer care. We conducted parallel surveys patients and physicians on TCM utilization. Methods. Two hundred forty-five 72 allopathic at Fudan University Shanghai Cancer Center completed questions their attitude towards TCM. Results. Patient mean age was 51, 60% female. Eighty-three percent had used Use greatest for herbal (CHM; 55.8%). Only 1.3%...
This randomized controlled trial examined the quality-of-life benefits of an expressive writing (EW) intervention for patients with renal cell carcinoma (RCC) and identified a potential underlying mechanism efficacy.Patients (N = 277) stage I to IV RCC were randomly assigned write about their deepest thoughts feelings regarding cancer or neutral topics (neutral [NW]) on four separate occasions. Patients completed Center Epidemiologic Studies Depression Scale (CES-D), MD Anderson Symptom...
This single-arm study evaluated feasibility, safety, and initial efficacy of electroacupuncture for thalidomide/bortezomib-induced peripheral neuropathy (PN) in cancer patients with multiple myeloma.Patients ≥ grade 2 received 20 acupuncture treatments over 9 weeks.For the 19 evaluable patients, Functional Assessment Cancer Therapy/Gynecological Oncology Group-Neurotoxicity (FACT/GOG/NTX) mean (SD) scores improved significantly between baseline week 13 (20.8 [9.6] vs 13.2 [8.5], p = 0.0002)....
Hypothesis This study examines moderators and mediators of a yoga intervention targeting quality-of-life (QOL) outcomes in women with breast cancer receiving radiotherapy.Methods Women undergoing 6 weeks radiotherapy were randomized to (YG; n = 53) or stretching (ST; 56) waitlist control group (WL; 54). Depressive symptoms sleep disturbances measured at baseline. Mediator (posttraumatic stress symptoms, benefit finding, cortisol slope) outcome (36-item Short Form [SF]-36 mental physical...
Background. In this international, multicenter study of patients undergoing lung transplantation (LT), we explored the association between amount intraoperative packed red blood cell (PRBC) transfusion and occurrence primary graft dysfunction (PGD) associated outcomes. Methods. The Extracorporeal Life Support in LT Registry includes data on recipients from 9 high-volume (>40 transplants/y) transplant centers (2 Europe, 7 United States). Adult who underwent bilateral orthotopic January...
N4-Acetylcytidine (ac4C) has been found to affect a variety of cellular and biological processes. For mechanistic understanding the roles ac4C in biology disease, we present an antibody-free, fluorine-assisted metabolic sequencing method detect RNA ac4C, called "FAM-seq". We successfully applied FAM-seq profile landscapes human 293T, HeLa, MDA cell lines parallel with reported acRIP-seq method. By comparison classic antibody method, that is convenient reliable for transcriptome-wide mapping...