- Autophagy in Disease and Therapy
- Phytoestrogen effects and research
- Cholesterol and Lipid Metabolism
- Cardiovascular Disease and Adiposity
- Nerve injury and regeneration
- Mesenchymal stem cell research
- Prostate Cancer Treatment and Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Neurological disorders and treatments
- Tissue Engineering and Regenerative Medicine
- Biochemical effects in animals
- Herbal Medicine Research Studies
- Polymer Surface Interaction Studies
- Hemostasis and retained surgical items
- Medicinal Plants and Bioactive Compounds
- Solid-state spectroscopy and crystallography
- Electrochemical sensors and biosensors
- Atherosclerosis and Cardiovascular Diseases
- Cancer-related molecular mechanisms research
- Superconductivity in MgB2 and Alloys
- Barrier Structure and Function Studies
- Electronic and Structural Properties of Oxides
- Alcoholism and Thiamine Deficiency
- Zeolite Catalysis and Synthesis
- 2D Materials and Applications
Inner Mongolia University for Nationalities
2025
Institute of Genetics and Developmental Biology
2024
Shaanxi Normal University
2018-2024
Zhejiang Cancer Hospital
2024
Chinese Academy of Sciences
2024
Zhejiang University
2023-2024
Zhejiang Lab
2024
University of Chinese Academy of Sciences
2024
Chongqing Medical University
2023
Tianjin Medical University
2021-2023
<italic>Codonopsis pilosula</italic> is a traditional Chinese medicine and food supplement that widely used in China. Oligosaccharides polysaccharides from <italic>C. display antifatigue antihypoxia activities.
Abstract Spinal cord injury (SCI) leads to fibrotic scar formation at the lesion site, yet heterogeneity of remains elusive. Here we show in distribution, origin, and function fibroblasts within scars after SCI mice female monkeys. Utilizing lineage tracing single-cell RNA sequencing (scRNA-seq), found that perivascular (PFs), meningeal (MFs), rather than pericytes/vascular smooth cells (vSMCs), primarily contribute both transection crush SCI. Crabp2 + /Emb+ (CE-F) derived from meninges...
Objective: This study aimed to identify potential target proteins of the Mongolian drug Shaosha-7 (SS-7) for amelioration ischemia-reperfusion injury following acute myocardial infarction and elucidate its comprehensive mechanism action in cardio-protection. Methods: The toxicity assay was conducted using zebrafish H9c2 cardiomyocytes, protective effects SS-7 against I/R were studied both vitro vivo. A TMT-based quantitative proteomics analysis performed explore global on rats. therapeutic...
The characteristics of refractory epilepsy change with disease progression. However, relevant studies are scarce due to the difficulty in obtaining long-term multi-site data from patients epilepsy. This work aimed provide a brain electrophysiological dataset 15 pilocarpine-treated rats temporal lobe (TLE). was constituted by local field potential (LFP) signal recorded 12 sites Papez circuit TLE, including spontaneous seizures and interictal fragments chronic period. LFP were saved MATLAB,...
This study aimed to prospectively observe the changes in neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte (PLR) before after percutaneous coronary intervention (PCI) their impact on prognosis of patients with acute syndrome (ACS).Blood samples from 205 ACS were collected at admission 24h 30 days post-PCI complete blood count. The Cox multivariate regression model was used analyze factors influencing major adverse cardiac events (MACE) PCI ACS. A receiver operating...
A-MPDA@Fe 3 O 4 @PVP can rapidly remove toxic ROS, regulate immune cells and activate the PPARγ/NF-κB pathway to treat hepatic ischemia-reperfusion injury.
Femur head necrosis, also known as osteonecrosis of the femoral (ONFH), is a widespread disabling pathology mostly affecting young and middle-aged population one major causes total hip arthroplasty in elderly. Currently, there are limited number different clinical or medication options for treatment reversal progressive ONFH, but their outcomes neither satisfactory nor consistent. In pursuit more reliable therapeutic strategies including recently emerged tissue engineering biomaterials...
Abstract The polyaniline (PANI)‐coated polystyrene (PS) latexes were synthesized, and the electrically conductive films prepared thereafter. weight ratio of PANI was 5%. Thermal analysis latices performed using DSC TGA. In this study, above PS glass transition temperature ( T g ). During film formation, effects annealing atmosphere (air or N 2 ) on resistance investigated. addition, morphology observed utilizing scanning electron microscopy. decreased in initial heating stage due to...
Ideal two-dimensional (2D) semiconductors with high mobility comparable to three-dimensional (3D) Si or GaAs are still lacking, hindering the development of high-performance 2D devices. Here in this work, using first-principles calculations and considering all electron-phonon couplings, we show that monolayer BX (X = P, As, Sb) honeycomb lattices have intrinsic phonon-limited carrier reaching record-high values 1200-14000 $cm^2V^{-1}s^{-1}$ at room temperature. Despite being polar band edges...
Osteoarthritis (OA) is one of the most common chronic diseases, in which inflammatory responses articular cavity induce chondrocyte apoptosis and cartilage degeneration. While mechanical loading reported to mitigate synovial inflammation, mechanism pathways for loading-driven improvement OA symptoms remain unclear. In this research, we evaluated effects on M1/M2 polarization macrophages via performing molecular, cytology, histology analyses. groups, cell layer lining was enlarged with an...
Bone marrow mesenchymal stem cell (BMMSC) transplantation is a promising approach for bone tissue regeneration; however, the osteogenic differentiation of BMMSCs needs to be improved. Our previous study proved that microRNA let-7a regulates immunosuppressive property BMMSCs, but roles in osteogenesis have not been elucidated. Here, we aimed identify and provide potential periodontal regeneration. were treated with mimics, inhibitor negative control. Then, aggregates (CAs) using each group...
Perovskite transition-metal oxides can undergo significant structural topological phase transition between perovskite structure, brownmillerite and infinite-layer structure under the external field through gain loss of oxygen ions, accompanied with changes in physical properties such as transportation, magnetism, optics. Topotactic transformation allows without losing crystalline symmetry parental provides an effective platform for utilizing redox reaction diffusion within metal oxides,...