A5086448770- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Ocular Infections and Treatments
- Plant Pathogens and Fungal Diseases
- Infectious Diseases and Mycology
- Ocular Surface and Contact Lens
- Helicobacter pylori-related gastroenterology studies
- Eosinophilic Esophagitis
- Probiotics and Fermented Foods
- Antimicrobial Resistance in Staphylococcus
- Sinusitis and nasal conditions
- Enzyme Production and Characterization
- Celiac Disease Research and Management
- Bacterial Identification and Susceptibility Testing
- Corneal Surgery and Treatments
- Microbial Inactivation Methods
- Amoebic Infections and Treatments
- Cancer Research and Treatments
- Galectins and Cancer Biology
- Parasitic infections in humans and animals
- Actinomycetales infections and treatment
- Parasites and Host Interactions
- Mycotoxins in Agriculture and Food
- Infections and bacterial resistance
- Viral Infections and Vectors
University of Szeged
2009-2024
University of Ljubljana
2019
Creative Research Enterprises (United States)
2019
Hungarian National Blood Transfusion Service
2019
Institute of Microbiology
2002
The presence of Candida species in urine (candiduria) is a common clinical finding, which may frequently represent colonization or contamination specimens, however, they be etiological agents urinary tract infections (UTIs) indicators underlying pathology the genitourinary system disseminated candidaemia. C. albicans most isolated genus, an increase occurrence non-albicans (NACS) has been reported, attributable to frequent exposure fluconazole.The aim this study was retrospectively assess...
The occurrence and genetic variability of Candida parapsilosis isolates in two Hungarian hospitals, located Debrecen Pécs, were examined. Among the 209 examined, 20 found to belong C. sensu lato, based on morphological, physiological molecular data. frequency (9.6%) was lower than that observed Europe but higher previously Hungary. lato also examined using random amplified polymorphic DNA (RAPD) analysis sequence intergenic transcribed spacer (ITS) region rRNA gene cluster. relatively high,...
ABSTRACT Trichoderma species are abundant in different agricultural habitats, but some representatives of this genus, mainly clade Longibrachiatum members also emerging as causative agents various human diseases with even fatal outcome. Strains these frequently show resistance to commonly used azole antifungals. Based on previous data it is hypothesized that isolates identified infections derive from environmental—including agricultural—origins. We examined longibrachiatum Rifai and...
Purpose: To report 2 cases of keratomycosis caused by Aspergillus tubingensis. Methods: The therapeutic courses were recorded for male patients, 52 and 78 years old, with fungal keratitis black strains. Morphological examination the isolates was carried out on malt extract agar plates. A segment β-tubulin gene used molecular identification. Antifungal susceptibilities determined E test method molds broth microdilution technique National Committee Clinical Laboratory Standards M38-A. Results:...
We report a case of Aspergillus tamarii keratitis. Ocular injury was known to be predisposing factor. Topical natamycin and econazole treatment subsequent systemic ketoconazole proved effective. The isolate identified by morphological characteristics sequence analysis as A. tamarii, member section Flavi not hitherto reported from keratomycosis.
ABSTRACT We report the first known case of fungal keratitis caused by Aspergillus nomius. Ocular injury was as a predisposing factor. The patient treated with natamycin and econazole eye drops, itraconazole ointment, oral ketoconazole. A therapeutic penetrating keratoplasty performed 16 days after presentation. sequence-based approach used to assign isolate species.
The purpose of this study was to evaluate the aetiology and susceptibility different Candida species originating from blood cultures received clinical wards University Hospital in Szeged, Hungary, 1996 2000. A total 145 episodes fungaemia occurred 68 patients. In 73.5% patients infections were due albicans, 7.3% C. parapsilosis, 5.9% krusei, 4.4% tropicalis 3% each glabrata, other spp. Cryptococcus neoformans. There no appreciable differences distribution yeast during 5-year period: albicans...
Human infections caused by Aspergillus brasiliensis have not yet been reported. We describe the first two known cases of fungal keratitis brasiliensis.A 49-year-old Indian Tamil woman agricultural worker came with pain and defective vision in right eye for one month. Meanwhile, a 35-year-old presented history corneal ulcer involving left 15 days. The strains isolated from these were originally suspected to belong section Nigri based on macro- micromorphological characteristics. Molecular...
We present a case of isolated sinusitis sphenoidalis caused by Trichoderma longibrachiatum, an emerging causal agent fungal infections with often fatal outcome. A strain was from secretion obtained the sinus rhinosinusitis patient and identified sequence analysis two loci as longibrachiatum Longibrachiatum Clade genus Trichoderma. T. can trigger pathomechanism in immunodeficient patients, but only rarely causes disease healthy people. The presented is unique because not immunocompromised.
Species belonging to the filamentous fungal genus Trichoderma are well known as potential candidates for biological control of plant pathogenic fungi and cellulase producers biotechnological importance. Several data were published in last decade also about clinical importance this genus, indicating that strains may be opportunistic pathogens immunocompromised patients. However, there is a lack information virulence factors strains. This study was designed examine extracellular proteolytic...
Potential virulence factors of 9 saprophytic and 12 clinical Trichoderma longibrachiatum strains were examined in the present study, order to compare their capacity cause infection humans. All able grow at temperatures up 40 °C pH values ranging from 2.0 9.0. Carbon nitrogen source utilization experiments revealed that all utilize a series basic amino acids both as sole carbon sources. The MIC tested antifungal drugs found be 0.016-8 µg/ml for amphotericin B, 64-256 fluconazole, 0.5-32...
We report a case of Neocosmospora vasinfecta keratitis in 55-year-old man. While the patient did not recall any specific trauma or eye injury, he might have sustained trivial wound during course his duties as farmer. Direct examination corneal scrapings revealed fungal filaments. As topical treatment with natamycin and econazole subsequent systemic ketoconazole therapy failed, full thickness therapeutic keratoplasty was performed. Post-operative amphotericin B clotrimazole combined...
Epidemiologic studies have revealed a decrease in the prevalence of Helicobacter pylori (H. pylori) infection Western Europe.To obtain data regarding H. Csongrád and Békés Counties Hungary, evaluate differences its between urban rural areas, establish factors associated with positive seroprevalence.One-thousand one healthy blood donors [male/female: 501/500, mean age: 40 (19-65) years] were enrolled this study. Subjects tested for IgG antibody positivity via enzyme-linked immunosorbent...
The incidence of Candida species causing bloodstream infections in the University Hospital Szeged, Hungary, between 1996 and 2009, susceptibilities these isolates to antifungal agents were evaluated.Automated blood culture systems (Vital, bioMérieux, Marcy-l'Etoile, France; BACTEC 9120, Becton-Dickinson Diagnostic Systems, Sparks, USA) used. vitro yeast determined by Etest method (AB Biodisk, Solna, Sweden).Bloodstream caused strains 231 cases during this period, 226 cultured from 216...
Although neonatal bloodstream infections may be caused by a variety of fungi, invasive fungaemia due to Candida pulcherrima in premature neonate has not been previously reported. We describe such case which antifungal susceptibility test data led successful therapy. A colonized catheter used for parenteral nutrition is presumed have the main source this persistent infection.
The purpose of this study was to evaluate the Etest as an in vitro antifungal susceptibility test method for different moulds originating from human samples and environment. A total 50 isolates (1 Acremonium, 18 Aspergillus, 2 Cladosporium, 1 Epicoccum, 15 Penicillium, Scopulariopsis 11 Trichoderma strains) were tested by Etest. Forty-six (92%) resistant fluconazole with minimal inhibitory concentrations (MICs) ³ 256 µg ml-1. There strains ketoconazole among Aspergillus niger, A. ochraceus...