A5058528342- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Plant Pathogens and Fungal Diseases
- Nail Diseases and Treatments
- Yeasts and Rust Fungi Studies
- Infectious Diseases and Mycology
- Mycotoxins in Agriculture and Food
- Fungal Biology and Applications
- Bee Products Chemical Analysis
- Essential Oils and Antimicrobial Activity
- Oral health in cancer treatment
- Bacterial Identification and Susceptibility Testing
- Plant Disease Resistance and Genetics
- Bacillus and Francisella bacterial research
- Head and Neck Cancer Studies
- Beetle Biology and Toxicology Studies
- Dermatology and Skin Diseases
- Insect and Pesticide Research
- Zoonotic diseases and public health
- Molecular Biology Techniques and Applications
- Gut microbiota and health
- Bacteriophages and microbial interactions
- Oral Health Pathology and Treatment
- Indoor Air Quality and Microbial Exposure
- bioluminescence and chemiluminescence research
National and Kapodistrian University of Athens
2015-2024
Harokopio University of Athens
2022
Statens Serum Institut
2020
Euromedica
2019
Sesame Workshop
2015
Athens Medical Center
1998-2014
Children's Hospital of Los Angeles
2012
Children's Hospital of Orange County
2012
Radboud University Nijmegen
2012
Panagiotis & Aglaia Kyriakou Children's Hospital
2009
Human and animal fungal pathogens are a growing threat worldwide leading to emerging infections creating new risks for established ones. There is need rapid accurate identification of enable early diagnosis targeted antifungal therapy. Morphological biochemical methods time-consuming require trained experts. Alternatively, molecular methods, such as DNA barcoding, powerful easy tool monophasic identification, offer practical approach species less demanding in terms taxonomical expertise....
Candida species are the third most common cause of pediatric health care-associated bloodstream infection in United States and Europe. To our knowledge, this report from International Pediatric Fungal Network is largest prospective, multicenter observational study dedicated to neonatal invasive candidiasis.From 2007 2011, we enrolled 196 25 patients with candidiasis.Non-albicans predominated (56%) (52%) age groups, yet albicans was both groups. Successful treatment responses were observed...
Until recently, Cryptococcus gattii infections occurred mainly in tropical and subtropical climate zones. However, during the past decade, C. humans animals Europe have increased. To determine whether were acquired from an autochthonous source or associated with travel, we used multilocus sequence typing to compare 100 isolates (57 40 human patients, 22 environment, 21 animals) 191 around world. Of 57 patient isolates, 47 (83%) obtained since 1995. Among 24 (60%) probably infection outside...
In order to elucidate the distribution of Cryptococcus neoformans and C. gattii in Mediterranean basin, an extensive environmental survey was carried out during 2012-2015. A total 302 sites located 12 countries were sampled, 6436 samples from 3765 trees collected 5% found be colonized by cryptococcal yeasts. isolated 177 13. 27% Ceratonia, 10% Olea, Platanus Prunus a lower percentage other tree genera. The 13 isolates five Eucalyptus, four two Pinus Olea trees. distributed all around whereas...
Introduction Soluble urokinase plasminogen activator receptor (suPAR) is an emerging inflammatory and immune biomarker. Whether suPAR level predicts the presence severity of coronary artery disease (CAD), incident death myocardial infarction (MI) in subjects with suspected CAD, unknown. Methods Results We measured plasma levels 3367 (67% CAD) recruited Emory Cardiovascular Biobank followed them for adverse cardiovascular (CV) outcomes MI over a mean 2.1±1.1 years. Presence angiographic CAD...
Invasive mold infections (IMIs) are a leading cause of mortality in immunocompromised children, yet there has never been an international epidemiologic investigation pediatric IMIs. This international, prospective cohort study was performed to characterize the epidemiology, antifungal therapy, and outcomes Children (≤18 years) with proven or probable IMIs were enrolled between August 2007 May 2011 at 22 sites. Risk factors, underlying diagnoses, treatments recorded. Outcomes assessed 12...
This study was designed to investigate the potential factors that influence prevalence of oral carriage Candida species in patients with type II diabetes mellitus. One hundred and twenty-eight diabetic (68 males 60 females, mean age 54 +/- 7 years) were sequentially enrolled along 84 (44 40 females 52 8 healthy subjects. Samples obtained by swabbing mucosa all participants. Yeast isolates identified germ tube test, API 32 ID system, chlamydospore production on 'cornmeal' Tween-80 agar. spp....
During a European Confederation of Medical Mycology (ECMM) prospective survey cryptococcosis in Europe (from July 1997 to December 1999) 655 cases were reported from 17 countries; 565 the completed questionnaires evaluable. Cryptococcosis was associated with HIV infection 77% (range 57.5-94%). Assessment laboratory data highlighted lack defined standard procedures for diagnosis cryptococcosis: antigen test not usually used screening, disease mainly recognised when meningitis occurred (65%...
In the absence of a functional dermatophyte-specific polymerase chain reaction (PCR), current diagnosis dermatophytoses, which constitute commonest communicable diseases worldwide, relies on microscopy and culture. This combination techniques is time-consuming notoriously low in sensitivity.Recent dermatophyte gene sequence records were used to design real-time PCR assay for detection identification dermatophytes clinical specimens less than 24 h.Two assays based amplification ribosomal...
ABSTRACT Matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) was used for an extensive identification study arthroconidial yeasts, using 85 reference strains from the CBS-KNAW yeast collection and 134 clinical isolates collected medical centers in Qatar, Greece, Romania. The test set included 72 ascomycetous yeasts ( Galactomyces , Geotrichum Saprochaete Magnusiomyces spp.) 147 basidiomycetous Trichosporon Guehomyces spp.). With minimal preparation...
We report the first case of Cryptococcus laurentii meningitis and a rare albidus cryptococcaemia in AIDS patients. Both infections were treated with amphotericin B flucytosine. The C. was controlled after 2 weeks treatment no evidence infection 20 months later. patient cryptococcaemia, despite B/flucytosine combination therapy, died on 14th day treatment. minimum inhibitory concentrations (MICs) for laurentii, as determined by Etest RPMI 1640 agar, 0.25 microg ml(-1) B, 1.25 flucytosine, 4...