- Viral Infections and Vectors
- Vector-borne infectious diseases
- Immune Cell Function and Interaction
- Streptococcal Infections and Treatments
- T-cell and B-cell Immunology
- Mosquito-borne diseases and control
- Ammonia Synthesis and Nitrogen Reduction
- Antimicrobial Peptides and Activities
- Neonatal and Maternal Infections
- Bacterial Infections and Vaccines
- Insect and Pesticide Research
- Pneumonia and Respiratory Infections
- S100 Proteins and Annexins
- Zoonotic diseases and public health
- Microbial Fuel Cells and Bioremediation
- Viral Infections and Immunology Research
- Immune Response and Inflammation
- Vector-Borne Animal Diseases
- Yersinia bacterium, plague, ectoparasites research
- Infective Endocarditis Diagnosis and Management
- Wastewater Treatment and Nitrogen Removal
- Transplantation: Methods and Outcomes
- Reproductive System and Pregnancy
- Asthma and respiratory diseases
Institute of Microbiology
2014-2023
Chinese Academy of Sciences
2023
University of Chinese Academy of Sciences
2023
Microbiology Institute of Shaanxi
2023
Guiyang Medical University
2021
Gaochun People's Hospital
2014
Jiangsu Province Hospital
2014
Shanxi Provincial Children's Hospital
2014
Harvard University
1985-1987
Brigham and Women's Hospital
1985
We used molecular methods to identify Rickettsia raoultii infections in 2 persons China. These had localized rashes around sites of tick bites. R. DNA was detected 4% Dermacentor silvarum ticks collected the same area China and 1 feeding detached from patient.
Nitrogen (N) loss is an important factor in N balance ecosystems. Traditionally, ammonia was considered as the sole initial oxidizing substrate for removal, and oxidation has long been a traditional cycle topic. Dirammox distinctive nitrogen removal mechanism it proceeds via direct aerobic conversion of to N2 single bacterium, yet its biocatalytic reactions enzymatic machinery remained elusive. By isotope tracing biochemical experiments, here we elucidate underlying N-oxidation [termed...
Abstract (LEW × BN)F 1 cardiac allografts are rejected within 8 days in unmodified LEW rats. ART18, a mouse anti‐rat IgG monoclonal antibody which binds specifically vitro to the interleukin 2 receptor (IL2R) molecule expressed primarily on activated T cells, prolongs allograft survival dose‐dependent fashion ca. 3 weeks (p < 0.001) after being administered for 10 transplantation. This effect was related specificity of IL2R, as therapy with ART62 (a recognizing MHC class I antigen but not...
Neisseria flavescens is an uncommon pathogen of human infection, pneumonia and empyema caused by N. rarely reported. Herein, we report a 56-year-old diabetic patient presenting necrotising due to infection. The main clinical manifestation this was high fever, sticky pus gradually aggravating dyspnea. chest computed tomography (CT) scan showed there are mass density areas around hilus the left lung, hollow sign with inflammation also appeared. A biopsy specimen taken from principal bronchus...
Background: To date, there have been few investigations on Candidatus Rickettsia tarasevichiae in rodents carried out China. In this study, we conducted surveillance for R. infection rodents. A total of 463 were captured at five survey sites Mudanjiang, Heilongjiang province, where patients reported. PCR targeting citrate synthase and outer membrane protein genes was performed positive amplicons sequenced. Result:Candidatus detected 1.29% the sampled from province. Only 2 13 (15.38%) Rattus...
The calcium-binding protein S100A4 demonstrates important regulatory roles in many biological processes including tumorigenesis and inflammatory disorders such as allergy. However, the specific mechanism of contribution to allergic diseases awaits further clarification. To address effect on regulation mast cell activation its impact Bone marrow-derived cultured cells (BMMCs) were derived from wild-type (WT) or S100A4-/- mice for vitro investigation. WT induced develop a passive cutaneous...
Abstract Northeastern China is a region of high tick abundance, multiple tick-borne pathogens and likely human infections. The spectrum diseases caused by has not been objectively evaluated in this for clinical management comparison with other regions globally where tick-transmitted are common. Based on symptoms, PCR, indirect immunofluorescent assay (or) blood smear, we identified described from patients recent bite seen at Mudanjiang Forestry Central Hospital. From May 2010 to September...
Background Group B streptococcus (GBS) is a leading cause of serious infections in infants. The extensive use tetracycline has led to the selection specific resistant and infectious GBS clones. sequence type (ST) 10 strain, causing invasive infants, becoming prevalent China. We aimed understand clinical microbiological characteristics this strain. Methods conducted retrospective study on infants with disease from largest women’s children’s medical center Shanxi collected data between January...
Children with congenital heart disease (CHD) have a predisposition to suffer from respiratory tract infections, such as bronchopneumonia (BP). In this study we investigated the characterization of lymphocyte subsets and regulatory T cells (Tregs) in these children. The frequencies were detected peripheral blood 400 children patients [100 BP only, 100 CHD (BPCHD), failure (BPHF), healthy volunteers] by using three-color flow cytometry. BPHF BPCHD groups, was analogous, lower levels CD3+,...