A5075050536- Vector-borne infectious diseases
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Vector-Borne Animal Diseases
- Insect and Pesticide Research
- Yersinia bacterium, plague, ectoparasites research
- Insect symbiosis and bacterial influences
- Viral Infections and Outbreaks Research
- Zoonotic diseases and public health
- COVID-19 epidemiological studies
- Toxin Mechanisms and Immunotoxins
- Plant and Fungal Interactions Research
- Disaster Response and Management
- Plant Parasitism and Resistance
- SARS-CoV-2 and COVID-19 Research
- Malaria Research and Control
- Genomics and Phylogenetic Studies
- Data-Driven Disease Surveillance
- Respiratory viral infections research
- Animal Virus Infections Studies
- Rabies epidemiology and control
- Influenza Virus Research Studies
- Dermatological diseases and infestations
- Hepatitis B Virus Studies
- Viral gastroenteritis research and epidemiology
Academy of Military Medical Sciences
2021-2025
Institute of Microbiology
2015-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Institute of Microbiology
2017-2024
Czech Academy of Sciences, Institute of Microbiology
2023
Shandong University
2023
Guizhou Provincial People's Hospital
2023
Anhui Medical University
2019-2020
Mudanjiang Medical University
2018
Chinese Academy of Sciences
2007
During 2014-2015, an outbreak of Ebola virus disease (EVD) swept across parts West Africa. No approved antiviral drugs are available for treatment currently. A retrospective clinical case series was performed EVD patients in Sierra Leone-China Friendship Hospital. Patients with confirmed were sequentially enrolled and treated either World Health Organization (WHO)-recommended supportive therapy (control group) from 10 to 30 October, or WHO-recommended plus favipiravir (T-705) 1 November...
The increasing incidence and range expansion of tick-borne diseases have caused global threats to human animal health under the background climate socioeconomic changes. As an efficient vector in transmission diseases, a growing burden by Ixodes persulcatus associated pathogens could not be underestimated. This study summarized distribution, hosts, I. persulcatus, predicted suitable habitats this tick species worldwide. An integrated database involving field survey, reference book,...
Background Tick-borne infectious diseases caused by the spotted fever group Rickettsia (SFGR) have continuously emerging, with many previously unidentified SFGR species reported. The prevalence of SFGRs in northwestern China remains unclear. This study aimed to examine and Anaplasma analyzing tick samples collected from Ningxia region. Methods During 2022–2023, ticks were Ningxia, China, screened using PCR amplify target genes (16S rRNA, gltA , ompA groEL ). amplicons confirmed Sanger...
To identify Candidatus Neoehrlichia mikurensis infection in northeastern China, we tested blood samples from 622 febrile patients. We identified 7 infected patients and natural foci for this bacterium. Field surveys showed that 1.6% of ticks 3.8% rodents collected residences were also infected.
We used molecular methods to identify Rickettsia raoultii infections in 2 persons China. These had localized rashes around sites of tick bites. R. DNA was detected 4% Dermacentor silvarum ticks collected the same area China and 1 feeding detached from patient.
Human babesiosis is an emerging health problem in China. Babesia were identified ticks, sheep, and humans northeastern China using polymerase chain reaction (PCR) followed by genetic sequencing. We enrolled residents who experienced a viral-like illness after recent tick bite or healthy residents. defined case the definition for developed US Centers Disease Control Prevention. A crassa–like agent was Ixodes persulcatus Haemaphysalis concinna ticks PCR The characterized through phylogenetic...
Abstract Background Malaria has re-emerged in Anhui Province, China, and this province was the most seriously affected by malaria during 2005–2006. It is necessary to understand spatial distribution of cases identify highly endemic areas for future public health planning resource allocation Province. Methods The annual average incidence at county level calculated using reported between 2000 2006 GIS-based analyses were conducted detect clustering level. Results Province from mapped show...
We conducted an investigation of Borrelia miyamotoi infections in humans and ticks northeastern China. Of 984 patients reporting recent tick bites, 14 (1.4%) were found to be infected with B. by PCR genomic sequencing. The had nonspecific febrile manifestations, including fever, headache, anorexia, asthenia, arthralgia. Rash, eschar, regional lymphadenopathy each observed 1 patient. Four (28.6%) hospitalized because severe disease. was detected 3.0% (19/627) Ixodes persulcatus, (2.8%) 36...
Introduction Ticks are the most important obligate blood-feeding vectors of human pathogens. With advance high-throughput sequencing, more and bacterial community virome in tick has been reported, which seems to pose a great threat people. Methods A total 14 skin specimens collected from tick-bite patients with mild severe symptoms were analyzed through meta-transcriptomic sequencings. Results Four bacteria genera both detected skins ticks, including Pseudomonas, Acinetobacter,...
Hepatitis B virus (HBV) is considered highly prevalent in West Africa. However, major gaps surveillance exist Sierra Leone. Although healthcare workers (HCWs) are at high risk for HBV infection, little known about the prevalence and knowledge of hepatitis among HCWs Leone.A cross-sectional study all No. 34 Military Hospital located Freetown, Leone, was conducted from March 20 to April 10, 2017. Whole blood collected screened markers using a one-step rapid immunochromatographic test with...
The emergence of tick-borne pathogens poses a serious threat to both human and animal health. There remains controversy about virome diversity in relation tick genus ecogeographical factors. We conducted the meta‑transcriptomic sequencing 155 pools ticks encompassing 7 species 3 genera collected from diverse geographical fauna Ningxia Province, China. Two Dermacentor were distributed predominantly grassland areas central eastern regions, with lowest viral diversity. Hyalomma found desert...
Little is known regarding tick-borne diseases in Mongolia, despite having 26% of the population still living nomadic pastoral lifestyles. A total 1497 adult unfed ticks: 261 Ixodes persulcatus, 795 Dermacentor nuttalli, and 441 Hyalomma asiaticum, were collected from three ecologically distinct regions Central Mongolia. Tick pools (n = 299) containing ~5 ticks each, tested for Rickettsia Tick-borne encephalitis virus (TBEV) using nested polymerase chain reaction, reverse transcription-PCR,...
Abstract The seasonal human coronaviruses (HCoVs) have zoonotic origins, repeated infections, and global transmission. objectives of this study are to elaborate the epidemiological evolutionary characteristics HCoVs from patients with acute respiratory illness. We conducted a multicenter surveillance at 36 sentinel hospitals Beijing Metropolis, China, during 2016–2019. Patients influenza‐like illness (ILI) severe infection (SARI) were included, submitted samples for screening by multiplex...
Abstract Background Human babesiosis is a worldwide disease caused by intraerythrocytic protozoa of the genus Babesia . It transmitted bites from ixodid ticks, and mechanically blood transfusion. primarily treated with quinine and/or atovaquone, which are not readily available in China. In this study, we developed novel treatment regimen involving doxycycline monotherapy patient severe venatorum infection as an alternative therapeutic medication. The aim our study to provide guidance for...
"Candidatus Neoehrlichia mikurensis" was detected by PCR in 4.0% (34/841) of the rodents tested this study. The 34 represented nine species from seven regions China. Phylogenetic analyses based on partial groEL and nearly entire 16S rRNA gene sequences agent revealed genetic diversity, which correlated with its geographic origins.
<b>Study question</b> Can avian influenza A (H7N9) virus be transmitted between unrelated individuals in a hospital setting? <b>Methods</b> An epidemiological investigation looked at two patients who shared ward February 2015, Quzhou, Zhejiang Province, China. Samples from the patients, close contacts, and local environments were examined by real time reverse transcriptase (rRT) polymerase chain reaction (PCR) viral culture. Haemagglutination inhibition microneutralisation assays used to...