A5100429477- Silicon and Solar Cell Technologies
- Thin-Film Transistor Technologies
- Silicon Nanostructures and Photoluminescence
- Semiconductor materials and interfaces
- Advancements in Battery Materials
- Neuroscience and Neuropharmacology Research
- Stability and Control of Uncertain Systems
- Neuroinflammation and Neurodegeneration Mechanisms
- MicroRNA in disease regulation
- Tryptophan and brain disorders
- Supercapacitor Materials and Fabrication
- Nanowire Synthesis and Applications
- Neurogenesis and neuroplasticity mechanisms
- Conducting polymers and applications
- Photovoltaic System Optimization Techniques
- Semiconductor materials and devices
- Integrated Circuits and Semiconductor Failure Analysis
- Circular RNAs in diseases
- Quantum Dots Synthesis And Properties
- Chalcogenide Semiconductor Thin Films
- Vascular Malformations Diagnosis and Treatment
- Vascular Malformations and Hemangiomas
- Vaccine Coverage and Hesitancy
- Sexual function and dysfunction studies
- Viral Infections and Vectors
Soochow University
2025
Shandong University
2005-2025
Yunnan University
2025
Shandong University of Arts
2024
University of Electronic Science and Technology of China
2024
Wuhan University of Technology
2024
Second Hospital of Shandong University
2024
Jiangsu Province Hospital
2024
Fudan University
2021-2024
Shandong Provincial Hospital
2022-2023
Enhancing neurogenesis within the hippocampal dentate gyrus (DG) is critical for maintaining brain development and function in many neurological diseases. However, neural mechanisms underlying depression remain unclear. Here, we show that microglia transfer a microglia-enriched microRNA, miR-146a-5p, via secreting exosomes to inhibit depression. Overexpression of miR-146a-5p DG suppresses spontaneous discharge excitatory neurons by directly targeting Krüppel-like factor 4 (KLF4)....
The increasing incidence and range expansion of tick-borne diseases have caused global threats to human animal health under the background climate socioeconomic changes. As an efficient vector in transmission diseases, a growing burden by Ixodes persulcatus associated pathogens could not be underestimated. This study summarized distribution, hosts, I. persulcatus, predicted suitable habitats this tick species worldwide. An integrated database involving field survey, reference book,...
Abstract A novel ferroelectric coupling photovoltaic effect is reported to enhance the open‐circuit voltage ( V OC ) and efficiency of CH 3 NH PbI perovskite solar cells. theoretical analysis demonstrates that this can effectively promote charge extraction as well suppress combination loss for an increased minority carrier lifetime. In study, a polymer P(VDF‐TrFE) introduced absorber layer in cells with proper cocrystalline process. Piezoresponse force microscopy (PFM) used confirm...
Agomelatine has been shown to be effective in the treatment of depression, but molecular mechanisms underlying its antidepressant effects have yet elucidated. Identification these would not only offer new insights into basis for depression also provide foundation development novel treatments this disorder.Intraperitoneal injection LPS was used induce depression-like behaviors rats. The interactions 5-HT2C reporter and Gαi-2 were verified by immunoprecipitation or immunofluorescence assay....
Posaconazole oral suspension is not approved for use in children younger than 13 years of age, and the optimal dosing regimen unclear. The target trough concentration posaconazole effective prevention invasive fungal infections adults influenced by multiple factors, but reports aged <13 remain limited. Therefore, primary objective this study was to evaluate potential risk factors affecting steady-state a large population Chinese children. This observational, single-center retrospectively...
Abstract This paper is concerned with the exact reachability of discrete‐time stochastic system partial information. The main contribution to obtain necessary and sufficient Gramian matrix criterion for systems key innovatively transform governed by forward difference equation into an equivalent backward equation. Simulation examples illustrate effectiveness results.
Neuroinflammation occupies a pivotal position in the pathogenesis of most nervous system diseases, including depression. However, underlying molecular mechanisms neuroinflammation associated with neuronal injury depression remain largely uncharacterized. Therefore, identifying potential and therapeutic targets would serve to better understand progression this condition.Chronic unpredictable stress (CUS) was used induce depression-like behaviors rats. RNA-sequencing detect differentially...
Major depression disorder (MDD) is a neuropsychiatric characterized by abnormal neuronal activity in specific brain regions. A factor that crucial maintaining normal functioning intracellular pH (pHi) homeostasis. In this study, we show chronic stress, which induces depression-like behaviors animal models, down-regulates the expression of hippocampal Na+/H+ exchanger isoform 1, NHE1, major determinant pHi neurons. Knockdown NHE1 CA1 pyramidal neurons leads to acidification, promotes...
Depression is a common psychological disease accompanied by mental disorders and somatic symptoms. However, the underlying mechanisms regarding pathogenesis of depression are still not clear. Neuronal damage resulting from inflammation considered to be one important risk factors for depression. Ginsenoside-Rg1, sterol extract extracted ginseng herbs, has been shown have neuroprotective effects against neurodegenerative diseases. Moreover, running exercise, simple behavioral therapy, recently...
Abstract Oxidative stress appears to play a role in the pathogenesis of diabetes mellitus erectile dysfunction (DMED). This study aimed investigate effect N‐acetylcysteine (NAC) on DMED streptozotocin‐induced diabetic mice and explore potential mechanisms. In present study, we show that an is mouse model as indicated by decreases intracavernous pressure responses electro‐stimulation well from results apomorphine test function. After treatment NAC, was increased. these mice, oxidative...
Anti-reflection coating (ARC) on crystalline silicon solar cell plays an important role in preventingpotential induced degradation (PID). In this work, we present a dual-layer ARC for increased resistance to potential degradation. By introducing thin SiOyNx layer between the SiNx and Si substrate, animproved chemical surface passivationwas obtained. A 0.1% absolute gainin conversion efficiencywas obtained compared result of single coated multi-crystalline cell. addition, SiOyNx/SiNx stack...
Abstract Findings from recent studies have revealed that microRNAs (miRNAs) are related to numerous neurological disorders. However, whether miRNAs regulate neuronal anomalies involved in the pathogenesis of depression remain unclear. In present study, we screened miRNA expression profiles CA1 hippocampus a rat model and found specific miRNA, microRNA‐211‐5p, was significantly down‐regulated depressed rats. When miR‐211‐5p up‐regulated these rats, apoptosis within area suppressed, effects...
The health of the elderly is one major challenges in today's ageing society. However, research on infectious diseases among limited. This study aimed to describe epidemiological characteristics and dynamics population aged ≥60 years Shandong province, China.Incidence data for were collected from Multi-Center Healthcare Big Data Platform January 2013 June 2017, which involved 550 432 persons. We compared incidence each disease category, stratified by age, gender, region. Annual percentage...
Neuronal injury is considered a critical risk factor in the pathogenesis of most neurological and neuropsychiatric diseases. However, underlying molecular mechanisms identification potential therapeutic targets for preventing neuronal associated with brain function remain largely uncharacterized. Therefore, identifying neural would put new insights into progression this condition provide novel strategies treatment these diseases.Stereotactic injection AAV virus was used to knock-down...
Curcumin is a polyphenol substance considered to be effective in the treatment of number neurodegenerative diseases. However, details regarding exact mechanisms for protective effects curcumin neuropsychiatric disorders, like depression, remain unknown. In pathogenesis major depressive disorder (MDD) it appears that dysregulation oxidative stress and immune systems, particularly within hippocampal region, may play critical role. Here, we show pre-treatment with (40 mg kg-1) alleviates...
Background Lung cancer is the leading malignant disease and cause of cancer-related death worldwide. Most patients with lung had insignificant early symptoms so that most them were diagnosed at an advanced stage. In addition to factors such as smoking, pollution, microbiome its metabolites play vital roles in development cancer. However, interaction between microbiota carcinogenesis lack systematically characterized controversial. Therefore, purpose this study was excavate features verify...