Xiao Chen

ORCID: 0000-0002-3669-3844
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About
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Research Areas
  • Genomics and Phylogenetic Studies
  • Marine and coastal ecosystems
  • Marine Biology and Ecology Research
  • Microbial Community Ecology and Physiology
  • Gut microbiota and health
  • Fermentation and Sensory Analysis
  • Bacterial Identification and Susceptibility Testing
  • Ocean Acidification Effects and Responses
  • Identification and Quantification in Food
  • Plant-Microbe Interactions and Immunity
  • Plant Pathogens and Fungal Diseases
  • Tryptophan and brain disorders
  • Marine Bivalve and Aquaculture Studies
  • Microbial Inactivation Methods
  • Diet and metabolism studies
  • Freshwater macroinvertebrate diversity and ecology
  • Geology and Paleoclimatology Research
  • Hydrocarbon exploration and reservoir analysis
  • Antimicrobial Resistance in Staphylococcus
  • Listeria monocytogenes in Food Safety
  • Aquaculture disease management and microbiota
  • Clostridium difficile and Clostridium perfringens research
  • Gastrointestinal motility and disorders
  • Geological and Geophysical Studies
  • Paleontology and Stratigraphy of Fossils

Research Institute of Petroleum Exploration and Development
2024-2025

South Australia Pathology
2021-2025

Flinders Medical Centre
2021-2025

Shandong University
2012-2024

State Forestry and Grassland Administration
2020-2024

Sichuan Agricultural University
2024

Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
2022-2024

Guangdong University of Technology
2024

Shanghai Normal University
2023-2024

Shanghai Maritime University
2024

Butyrate, one of the key aroma compounds in Luzhou-flavor baijiu, is synthesized through two alternative pathways: butyrate kinase (buk) and butyryl-CoA:acetate CoA-transferase (but). A lack knowledge butyrate-producing microorganisms hinder our ability to understand flavor formation mechanism baijiu. Here, temporal dynamics microbial metabolic profiling fermented grains (FG) was explored via PICRUSt based on 16S rRNA gene sequences. We found Bacilli Bacteroidia were major potential...

10.3389/fmicb.2019.01397 article EN cc-by Frontiers in Microbiology 2019-06-21

Abstract Environmental filtering and spatial processes have been associated with variation in ecological communities biodiversity; however, their relative importance on multiple dimensions of beta diversity has not fully explored montane streams. Here, we examined the contribution local, catchment climate environmental variables factors to three macroinvertebrate upper Han River Basin. Taxonomic, functional, phylogenetic diversities respective turnover nestedness components were calculated...

10.1002/lno.11599 article EN Limnology and Oceanography 2020-09-23

The role of respiratory tract microbes and the relationship between gut microbiomes in coronavirus disease 2019 (COVID-19) remain uncertain. Here, metagenomes sputum fecal samples from 66 patients with COVID-19 at three stages progression are sequenced. Respiratory tract, microbiome, peripheral blood mononuclear cell (PBMC) analyzed to compare microbiota intensive care unit (ICU) non-ICU (nICU) determine relationships microbiome immune response. In significantly fewer Streptococcus,...

10.1002/advs.202200956 article EN cc-by Advanced Science 2022-07-03

As many oil and gas reservoirs approach depletion stages in the future, alongside growing energy storage demands, constructing facilities becomes critical for ensuring a stable natural supply. Consequently, comprehensive geological analysis is essential to evaluate feasibility of converting depleted into facilities. The W reservoir Sichuan Basin, China, nearing presents potential conversion facility. This study provides evaluation determine its such conversion. Exploration production data...

10.1038/s41598-024-84589-5 article EN cc-by-nc-nd Scientific Reports 2025-01-02

A novel Gram-stain-positive, rod-shaped, obligately anaerobic, non-motile, spore-forming and binary fission encapsulated bacterium, designated strain JN500901T, was isolated from a mud cellar which has been continuously used for the fermentation of Chinese strong-flavour baijiu over 100 years. Growth JN500901Toccurred at pH 4.5-8.0 (optimum, 5.0), 20-40 °C (37 °C), 0-2 % (w/v) NaCl 0-10 (v/v) ethanol. The Biolog assay revealed that JN500901T metabolized d-fructose, l-fucose, isomaltulose...

10.1099/ijsem.0.003254 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2019-02-08

Hypoxia is a major cause of fish morbidity and mortality in the aquatic environment. Hypoxia-inducible factors are very important modulators transcriptional response to hypoxic stress. In this study, we characterized conducted functional analysis hypoxia-inducible factor HIF1α its inhibitor HIF1αn Nile tilapia (Oreochromis niloticus). By cloning Sanger sequencing, obtained full length cDNA sequences for (2686bp) (1308bp), respectively. The CDS includes 15 exons encoding 768 amino acid...

10.1371/journal.pone.0173478 article EN cc-by PLoS ONE 2017-03-09

We determined the complete mitochondrial genome (mitogenome) of Acrossocheilus wenchowensis. It is first report mitogenome in genus Acrossocheilus. The total length A. wenchowensis 16,591 bp, consisting 13 protein-coding genes, 2 rRNA 22 transfer RNA genes and a A+T rich control region. gene order transcriptional orientation are similar to most vertebrates. overall base composition 31.00% A, 27.70% C, 16.30% G 25.00% T. termination-associated sequence conserved blocks were identified

10.3109/19401736.2012.752483 article EN Mitochondrial DNA 2013-01-11

This study was focus on investigating the community composition of endophytic fungi in leaves Vaccinium dunalianum Wight. Based a combination morphological features and molecular evidence, 239 fungal isolates belonging to 33 genera including 62 species were obtained identified. By comparing relative abundance (RA) values, most frequent belonged Phyllosticta Guignardia with RA 26·78 14·22% respectively. Of which, strains P. capitalensis G. mangiferae potential antimicrobial activity dominant...

10.1111/lam.13345 article EN Letters in Applied Microbiology 2020-07-03

Metacommunity ecology highlights the importance of integrating simultaneously environmental filtering and spatial processes, such as mass effects dispersal limitation, into investigation community assembly. However, few studies to date have tried examine limitation independent ecological mechanisms along with in shaping biological communities river networks. We examined relative three factor groups, i.e., variables, within-river factors (indicative effects) basin identity (referring...

10.1016/j.ecolind.2020.107188 article EN cc-by-nc-nd Ecological Indicators 2020-12-05

To compare the 6-month efficacy of intravitreal injection conbercept or ranibizumab for patients with polypoidal choroidal vasculopathy (PCV).This is a retrospective case-control study involved 79 PCV eyes 77 patients. The were treated an either (n = 44) 35). Three monthly loading doses injected and followed by retreatment as needed. best-corrected visual acuity angiographic characteristics evaluated after 6 months.The mean logarithm minimum angle resolution had improved from 0.86 (Snellen...

10.1097/iae.0000000000002035 article EN Retina 2018-01-23

Irinotecan (CPT-11) is an important anticancer drug in management of advanced colon cancer. A marked protective effect on CPT-11-induced blood and gastrointestinal toxicity obtained by combination St. John ' s wort (SJW) recent clinical rat studies. However, the mechanism unclear. This study aimed to explore effects SJW pharmacokinetics CPT-11 its major metabolites (SN-38 SN-38 glucuronide) rats underlying mechanisms using several vitro models. Short-term (3 days) long-term (14 pretreatment...

10.2174/138920007779815995 article EN Current Drug Metabolism 2007-02-01

To carry out a nationwide epidemiologic survey on the neonates in urban hospitals with an attempt to understand disease spectrum and treatment outcomes of hospitalized China.The clinical data 43,289 from 86 47 Chinese cities (22 provinces) between January 1, 2005 December 31, were retrospectively analyzed.The male:female ratio was 1.73:1. Premature infants accounted for 26.2% neonates, which higher than that reported 2002 (19.7%). The top three diseases during neonatal period jaundice,...

10.3978/j.issn.2224-4336.2011.10.01 article EN PubMed 2012-07-01

Hypercholesterolemia is a major risk factor for cardiovascular disease (CVD). Probiotics are one of the most popular dietary supplements hypercholesterolemia, but there questions as to whether differences between probiotics and cholesterol-lowering drugs like atorvastatin (ATO) both in effectiveness underlying mechanisms. In this study, hypocholesterolemia effects 4 probiotic strains were investigated compared with ATO, focusing on their impacts gut microbiota. A hypercholesterolemia model...

10.1039/c9fo00444k article EN Food & Function 2019-01-01

is one group of main primary producers and plays a key role in oceanic carbon fixation transformation. To explore how the temperature rise affects bioavailability

10.3389/fmicb.2022.838707 article EN cc-by Frontiers in Microbiology 2022-04-19
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