A5101875744- Genomics and Phylogenetic Studies
- Identification and Quantification in Food
- Thyroid Cancer Diagnosis and Treatment
- Aquaculture disease management and microbiota
- Thyroid and Parathyroid Surgery
- Fish Biology and Ecology Studies
- Cardiac Fibrosis and Remodeling
- Ichthyology and Marine Biology
- Coastal wetland ecosystem dynamics
- Molecular Biology Techniques and Applications
- Pregnancy and preeclampsia studies
- Vibrio bacteria research studies
- Mitochondrial Function and Pathology
- Marine and coastal plant biology
- Marine and coastal ecosystems
- Gut microbiota and health
- Electrospun Nanofibers in Biomedical Applications
- Cancer-related molecular mechanisms research
- Martial Arts: Techniques, Psychology, and Education
- Marine Bivalve and Aquaculture Studies
- Blood Pressure and Hypertension Studies
- Physical Education and Training Studies
- Heme Oxygenase-1 and Carbon Monoxide
- Coronary Artery Anomalies
- Ocean Acidification Effects and Responses
Zhejiang Mariculture Research Institute
2009-2024
Peking Union Medical College Hospital
2016-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2024
Chinese People's Armed Police Force
2012-2023
Chinese People's Armed Police General Hospital
2023
University of South China
2021
Shanghai Pulmonary Hospital
2020
Tongji University
2020
Fudan University
2020
Tianjin Medical University
2012-2019
Post-infarction cardiovascular remodeling and heart failure are the leading cause of myocardial infarction (MI)-driven death during past decades. Experimental observations have involved intestinal microbiota in susceptibility to MI mice; however, humans, identifying whether translocation gut bacteria systemic circulation contributes events post-MI remains a major challenge.Here, we carried out metagenomic analysis characterize cohort 49 healthy control individuals, 50 stable coronary disease...
Abstract Recurrence and metastasis are the major issues for papillary thyroid cancer (PTC). Current morphological molecular classification systems not satisfied PTC diagnosis due to lacking variant‐specific criteria high signal‐to‐noise in mutation‐based diagnosis, respectively. Importantly, intratumor heterogeneity is largely lost current system, which can be resolved by single cell RNA sequencing (scRNA‐seq). However, scRNA‐seq loses spatial information features. Herein, integrated...
Objective: Curcumin is a wide-spectrum cellular protector with antiinflammatory, antioxidizant, and antifibrotic effects. This study was conducted to investigate its effects on myocardial collagen remodeling in pressure overloaded rabbits. Methods Results: Pressure rabbits were established by partial abdominal aorta ligation. The divided into the sham-operation group, vehicle group curcumin group. administered orally at dose of 100 mg/kg·d 10 ml 2.5% polyethylene glycol solution other 2...
We determined the complete mitochondrial genome (mitogenome) of Acrossocheilus wenchowensis. It is first report mitogenome in genus Acrossocheilus. The total length A. wenchowensis 16,591 bp, consisting 13 protein-coding genes, 2 rRNA 22 transfer RNA genes and a A+T rich control region. gene order transcriptional orientation are similar to most vertebrates. overall base composition 31.00% A, 27.70% C, 16.30% G 25.00% T. termination-associated sequence conserved blocks were identified
We determined the complete mitochondrial genome of red stingray Dasyatis akajei. It is 17,658 bp in length, including 13 protein-coding genes, 2 ribosomal RNA 22 transfer genes and a control region. The gene arrangement transcriptional direction were same as those typical vertebrate mitogenomes. overall base composition heavy-strand 28.8% T, 26.8% C, 30.9% A 13.6% G, with slight + T bias 59.7%. origin light-strand replication (OL) was identified between tRNA-Asn tRNA-Cys genes....
The study aimed to unravel the interaction between ocean acidification and solar ultraviolet radiation (UVR) in Chaetoceros curvisetus . cells were acclimated high CO 2 (HC, 1000 ppmv) low concentration (control, LC, 380 for 14 days. Cell density, specific growth rate chlorophyll measured. then exposed PAB (photosynthetically active (PAR) + UV-A UV-B), PA (PAR UV-A) or P 60 min. Photochemical efficiency (ΦPSII), relative electron transport (rETR) recovery of ΦPSII determined. HC induced...
Cell cycle checkpoint kinase 2 (CHK2) performs essential cellular functions and might be associated with tumorigenesis tumor progression. Here, we explored the function molecular mechanisms of CHK2 in progression papillary thyroid cancer (PTC).The expression levels both total activated (p-CHK2) tissues from 100 PTC patients were detected evaluated using immunohistochemistry. The roles on cell proliferation, invasion, migration, apoptosis stem (CSC) markers investigated by CCK-8, Transwell,...
Abstract Evidence has shown that angiotensin II type 1 receptor antagonists have lower blood pressure and target organ protective effects, but this is not the case for drug allisartan isoproxil. The aim of study was to evaluate effects isoproxil on injury in patients with mild moderate essential hypertension. In total, 80 hypertensive participants were randomly divided into an group a nifedipine (n = 40 per group), their measured once month 6 months. A 2-dimensional echocardiogram performed...
The impact of myocardial bridge (MB) on left ventricular (LV) systolic synchrony is insufficiently understood.Thirty-five subjects with isolated mid-left, anterior, descending artery (LAD) MB, preserved LV ejection fraction (LVEF > 50%), and otherwise, normal coronary angiogram were identified from 3607 patients who underwent diagnostic angiography evaluated by tissue Doppler imaging real-time three-dimensional echocardiography (RT3DE). Control consisted 26 age sex-matched angiographically...
In this study, the complete mitochondrial genome of Blotchy swell shark Cephaloscyllium umbratile was determined. It a circle molecular (16 698 bp), contained 37 genes with typical order to that most other vertebrates. The nucleotide composition 31.0% A, 24.0% C, 14.0% G, and 31.3% T. There were 26 bp short intergenic spaces located in 11 gene junctions 28 overlaps 7 whole mitogenome. Two start codons (GTG ATG) two stop (TAG TAA/T) used protein-coding genes. phylogenetic result showed C....
Lung cancer is the leading cause of incidence and mortality. Non-small cell lung (NSCLC) accounts for vast majority cancer, which lacks comprehensive prognostic biomarkers to predict prognosis patients. This research was performed assess potential role circular RNAs (circRNAs) in patients with NSCLC.We searched following databases: PubMed, Web Science, Embase, Ovid MEDLINE(R) up May 20, 2019 identify studies explored association between circRNAs NSCLC. Newcastle-Ottawa Scale (NOS) applied...
Background Preeclampsia (PE) mainly occurs in pregnant women and is hereditary. Several genome-wide association studies (GWAS) on Caucasian samples have reported some gene loci that are associated with preeclampsia. However, these not reached consistent conclusions. No previous GWAS has examined preeclampsia the Chinese Han population.
In this study, the complete mitochondrial genome of Bowmouth guitarfish Rhina ancylostoma (Rajiformes, Rhinobatidae) was first determined. The total length circle DNA 17 217 bp, consisted 37 genes with a typical gene order in vertebrate mitogenome. It had 42 bp short intergenic spaces and 40 overlaps. nucleotide composition R. as follows: A, 33.0%; C, 25.1%; G, 12.6% T, 29.3%. Two start codons (GTG ATG) two stop (TAG TAA/T) were used protein-coding genes. 22 tRNA ranged from 67 (tRNA-Ser2)...
The complete mitochondrial genome of Sinibrama macrops was first determined in this study. is 16,626 bp length, including 13 protein-coding genes, 2 ribosomal RNA 22 transfer genes and 1 control region. Its gene arrangement translation direction were identical to those other typical vertebrates. overall base composition 30.7% A, 27.9% C, 16.7% G 24.7% T, with the negative GC skew value ( − 0.251). In a long term, S. confused wui, which confirmed as an invalid species by recent morphological...
Abstract Methods derived from immunoassays and aptasensors have been established for monitoring of carcinoembryonic antigen (CEA) in biological fluids, but most involved complex procedure various reactions. We designed an uncomplicated convenient electrochemical aptasensing platform the quantitative CEA on multifunctionalized magnetic beads with a handheld pH meter as read‐out. Initially, CEA‐specific aptamers were covalently conjugated to beads, then hybridized glucose oxidase‐labeled...