A5011118108- Salmonella and Campylobacter epidemiology
- Viral gastroenteritis research and epidemiology
- Bacteriophages and microbial interactions
- Clostridium difficile and Clostridium perfringens research
- Veterinary medicine and infectious diseases
- Vibrio bacteria research studies
- Genomics and Phylogenetic Studies
- Listeria monocytogenes in Food Safety
- Escherichia coli research studies
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Antimicrobial Resistance in Staphylococcus
- Digestive system and related health
- Photosynthetic Processes and Mechanisms
- Postharvest Quality and Shelf Life Management
- Zoonotic diseases and public health
- Probiotics and Fermented Foods
- Streptococcal Infections and Treatments
- Animal Nutrition and Physiology
- Infant Nutrition and Health
- Pharmacological Effects and Assays
- Child Nutrition and Water Access
- Aquaculture disease management and microbiota
- Microbial Community Ecology and Physiology
- Insect and Pesticide Research
University of Arizona
2013-2025
University of California Division of Agriculture and Natural Resources
2024
Arizona Western College
2023-2024
Texas A&M University
2023-2024
AstraZeneca (United States)
2022
California State University, Northridge
2015-2021
United States Department of Agriculture
2014
Western Regional Research Center
2014
Agricultural Research Service
2014
University of California, Davis
2013
Antimicrobial resistant (AMR) Campylobacter is a global health threat, however there limited information on genomic determinants of resistance in low- and middle-income countries. We evaluated AMR using collection whole genome sequenced jejuni C. coli isolates from Iquitos, Peru. two pediatric cohort studies enriched with that demonstrated to ciprofloxacin azithromycin were mined for determinants. The gyrA mutation leading the Thr86Ile amino acid change was only associated fluoroquinolone...
Abstract Background Although serotype O157:H7 is the predominant enterohemorrhagic Escherichia coli (EHEC), outbreaks of non-O157 EHEC that cause severe foodborne illness, including hemolytic uremic syndrome have increased worldwide. In fact, serotypes are now estimated to over half all Shiga toxin-producing (STEC) cases, and infections frequently associated with O26, O45, O103, O111, O121, O145. Currently, there no complete genomes for O145 in public databases. Results We determined genome...
Akkermansia muciniphila is a mucin-degrading bacterium found in the human gut and often associated with positive health. However, despite being detected by as early 1 month of age, little known about role infant gut. Human milk oligosaccharides (HMOs) are abundant components structurally similar to that comprise mucin, preferred growth substrate human-associated Akkermansia. A limited subset intestinal bacteria has been shown grow well on HMOs mucin. We therefore examined ability genomically...
Abstract In this study, we aimed to examine the association between gastrointestinal (GI) symptom presence during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and prevalence of GI symptoms development post-infectious irritable bowel (PI-IBS). We used data from a prospective cohort logistic regression status confirmed SARS-CoV-2 persistent at ≥45 days. also report incidence PI-IBS following infection. Of 1475 participants in 33.8% ( n = 499) had Cases with an odds...
ABSTRACT In this work, we investigated the Campylobacter jejuni dps (DNA binding protein from starved cells) gene for a role in biofilm formation and cecal colonization poultry. vitro assays were conducted with stationary-phase cells cell culture plates under microaerophilic conditions. These studies demonstrated significant (>50%) reduction by C. mutant compared to that wild-type strain. Studies poultry also importance of host . Real-time PCR analysis mRNA extracted contents infected...
Campylobacter is the primary cause of bacterial diarrhea in United States and can lead to development postinfectious autoimmune neuropathy known as Guillain-Barré syndrome. Also, drug-resistant campylobacters are becoming a serious concern both locally abroad. In low- middle-income countries (LMICs), infection with linked high rates morbidity, growth stunting, mortality children, breastfeeding important for infant nutrition, development, protection against infectious diseases. this study, we...
Introduction Postacute sequelae of SARS-CoV-2 infection (PASC) are extensive. Also known as long COVID, primary outcomes reported neurologic, cardiac and respiratory in nature. However, several studies have also an increase gastrointestinal (GI) symptoms syndromes following COVID-19. This study PASC will include extensive analyses GI symptoms, determine if people with pre-existing irritable bowel syndrome (IBS) at higher risk developing generally or PASC-GI, which biomarkers impacted to what...
Abstract The genetic structure of bacterial populations can be related to geographical locations isolation. In some species, there is a strong correlation between distance and distance, which caused by different evolutionary mechanisms. Patterns ancient admixture in Helicobacter pylori reconstructed concordance with past human migration, whereas Mycobacterium tuberculosis it the lack recombination that causes allopatric clusters. Campylobacter , analyses genomic data molecular typing have...
Acute hepatopancreatic necrosis disease (AHPND) is a devastating condition impacting marine shrimp production worldwide. The objective of this study was to evaluate the effects four probiotic formulations on Pacific white (Litopenaeus vannamei) infected with pathogenic Vibrio parahaemolyticus causing AHPND. In addition, bacterial community composition analyses gastrointestinal tract (GIT) and aquaculture water before after infection were conducted by sequencing variable region 4 16S rRNA...
Campylobacter is the leading bacterial cause of gastroenteritis worldwide and its incidence especially high in low- middle-income countries (LMIC). Disease epidemiology LMICs different compared to income like USA or Europe. Children commonly have repeated chronic infections even absence symptoms, which can lead deficits early childhood development. In this study, we sequenced characterized C. jejuni (n = 62) from a longitudinal cohort study children under age 5 with without diarrheal...
• Drug-induced nephrotoxicity is an increasingly recognized complication of a wide variety therapeutic agents. The three the most commonly used drug groups are reviewed in this article. They include antibiotics, radiocontrast agents, and nonsteroidal anti-inflammatory drugs. Since clinical spectrum drug-induced broad, it imperative that clinician recognize these nephrotoxic syndromes while they reversible with discontinuation offending drug. (<i>Arch Intern Med</i>1987;147:1213-1218)
Campylobacter jejuni is one of the leading causes bacterial gastroenteritis in world; however, there only complete genome sequence a poultry strain to date. Here we report and annotation second strain, C. S3. This has been shown be nonmotile, poor invader vitro, colonizer after minimal vitro passage.
Iron acquisition is an absolute requirement by most microorganisms for host survival. In this work, we investigated the Campylobacter jejuni iron binding Dps protein a potential role in virulence. vitro assays using J774A.1 macrophage-like cells demonstrated 2.5 log reduction C. survival of mutant and four logs invasion HEp-2 epithelial compared to wild-type strain. To examine dps gene pathogenesis, piglet model was used challenge studies. vivo inoculation studies newborn piglets with...