A5032341569- Acupuncture Treatment Research Studies
- Ginseng Biological Effects and Applications
- Neonatal Respiratory Health Research
- Vagus Nerve Stimulation Research
- Cardiac, Anesthesia and Surgical Outcomes
- Neuroinflammation and Neurodegeneration Mechanisms
- Pain Mechanisms and Treatments
- RNA modifications and cancer
- Music Therapy and Health
- Birth, Development, and Health
- Congenital Diaphragmatic Hernia Studies
- Patient Safety and Medication Errors
- Biochemical effects in animals
- Artificial Intelligence in Healthcare and Education
- Machine Learning in Healthcare
- COVID-19 diagnosis using AI
- Neurological Disease Mechanisms and Treatments
- Biomarkers in Disease Mechanisms
- Bone Metabolism and Diseases
- Cytokine Signaling Pathways and Interactions
- Healthcare cost, quality, practices
- Traditional Chinese Medicine Analysis
- Healthcare and Venom Research
- Ferroptosis and cancer prognosis
- Radiation Dose and Imaging
Wenzhou Medical University
2013-2024
First Affiliated Hospital of Wenzhou Medical University
2013-2024
First Hospital of China Medical University
2017
Abstract C‐Jun N‐terminal kinase (JNK) is a pivotal MAPK (mitogen‐activated protein kinase), which activated by ischemia brain injury and plays fairly crucial function in cerebral ischemic injury. Emerging studies demonstrated that JNK‐IN‐8 (a JNK inhibitor with high specificity) regulates traumatic through controlling neuronal apoptosis inflammation. However, the of stroke mechanisms underlying about neuroprotection are not well understood. In this work, male rats were treated after...
To evaluate whether ferroptosis is involved in hyperoxic acute lung injury (HALI) and its mechanisms through the HALI model.HE staining was used to assess pathology after establishment of neonatal rat model. ELISA detect ROS, GPX4, GSH expression. Prussian blue Western Blot were iron deposition expression ferroptosis-related proteins, respectively.The group showed pathological changes with larger fewer alveoli thicker alveolar septa HE staining. detected significant tissue group. GSH, GSS,...
Glioblastoma (GBM) ranks the most common and aggressive primary brain malignant tumor worldwide. However, survival rates of patients remain very poor. Therefore, molecular oncology GBM are urgently needed. In this study, we performed an integrative analysis DNA methylation gene expression to identify key epigenetic genes in GBM. The Cancer Genome Atlas (TCGA) database were downloaded. After data preprocessing, identified 4,881 differentially expressed (DEGs) between normal samples, including...
Purpose: Episodes of acute emotional or physical stress can have significant adverse effects on the hippocampus. Ginsenoside Rb1, most predominant ginsenoside present in Panax species, has been reported to show a neuroprotective effect. The purpose this study was investigate influence Rb1 plasma corticosterone (CORT) and adrenocorticotropic hormone (ACTH) levels hippocampal brain-derived neurotrophic factor (BDNF) tyrosine kinase B (TrkB) rats subjected immobilization stress. Methods: Wistar...
Introduction: Electro-acupuncture (EA) can significantly improve inflammatory response, but the specific mechanism is not clear. Limb ischemia-reperfusion (I/R) first produces reactions in lungs. In this study, EA on Zusanli (ST36) and Sanyinjiao (SP6) were used to explore of improving tissue inflammation by sciatic nerve disconnection. Material Methods: A total 56 male Sprague-Dawley rats randomly divided into sham group, model SEA SNC+EA TNC+EA group PNC+EA group. The groups given any...
Abstract c-Jun N-terminal kinase (JNK), a mitogen activated protein kinase, is in ischemia brain injury and plays an important role cerebral ischemic injury. Emerging studies demonstrated that JNK-IN-8 (a specific JNK inhibitor) regulates traumatic through controlling neuronal apoptosis inflammation. However, the of stroke underlying mechanisms involving neuroprotection remain poorly understood. In present study, male rats were subjected to tMCAO (transient middle artery occlusion) followed...
Admission lactate level has been reported as a useful marker of mortality. In this study, we compared the relative value different indices to predict survival in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI).This was retrospective observational study including consecutive STEMI PCI who admitted Coronary Care Unit First Affiliated Hospital Wenzhou Medical University between 2014 and 2017. The predictive for...
Acupuncture promotes the recovery of gastrointestinal function and provides analgesia after major abdominal surgery. The effects transcutaneous electrical acupoint stimulation (TEAS) remain unclear.To explore potential TEAS on gastrectomy colorectal resection.Patients scheduled for or resection were randomized at a 2:3:3:2 ratio to receive: (1) maximum tolerable current 30 min immediately prior anesthesia induction entire duration surgery, plus two 30-min daily sessions 3 consecutive days...