A5071023871- Medical Imaging Techniques and Applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Advanced X-ray and CT Imaging
- Inflammatory Bowel Disease
- Radiation Dose and Imaging
- MRI in cancer diagnosis
- Pancreatic and Hepatic Oncology Research
- Colorectal and Anal Carcinomas
- Anorectal Disease Treatments and Outcomes
- Diagnosis and treatment of tuberculosis
- Medical Imaging and Pathology Studies
- Prostate Cancer Treatment and Research
- Neuroendocrine Tumor Research Advances
- Autoimmune and Inflammatory Disorders
- Orthopedic Surgery and Rehabilitation
- Microscopic Colitis
- Liver Disease and Transplantation
- Elbow and Forearm Trauma Treatment
- Ultrasound Imaging and Elastography
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Endometriosis Research and Treatment
- Vascular Tumors and Angiosarcomas
- Intestinal Malrotation and Obstruction Disorders
Mayo Clinic in Arizona
2010-2024
Mayo Clinic
2012-2024
WinnMed
2017-2024
Western University
2024
University College London
2024
Cleveland Clinic
2024
Siemens Healthcare (United States)
2019
Brigham and Women's Hospital
2018-2019
University of California, San Francisco
2015-2016
University of California System
2016
The purpose of this work was to evaluate the effect androgen receptor (AR) inhibition on prostate-specific membrane antigen (PSMA) uptake imaged using <sup>68</sup>Ga-PSMA-11 PET in a mouse xenograft model and patient with castration-sensitive prostate cancer. <b>Methods:</b> We 3 groups 4 mice bearing LNCaP-AR xenografts before 7 d after treatment ARN-509, orchiectomy, or control vehicle. Additionally, we one cancer wk deprivation therapy (ADT). Uptake pre- posttreatment imaging measured...
Most noise reduction methods involve nonlinear processes, and objective evaluation of image quality can be challenging, since cannot fully characterized on the sole basis level at computed tomography (CT). Noise spatial correlation (or texture) is closely related to detection characterization low-contrast objects may quantified by analyzing power spectrum. High-contrast resolution measured using modulation transfer function section sensitivity profile generally unaffected reduction....
Background Clinical decision making and drug development for fibrostenosing Crohn disease is constrained by a lack of imaging definitions, scoring conventions, validated end points. Purpose To assess the reliability MR enterography features to describe strictures determine correlation with stricture severity. Materials Methods A retrospective study patients symptomatic terminal ileal who underwent at tertiary care centers (Cleveland Clinic: September 2013 November 2020; Mayo February 2008...
Immunoglobulin light-chain (AL) amyloidosis affects multiple systemic organs. However, determination of the precise extent organ involvement remains challenging. Targeted amyloid imaging with 18F-florbetapir PET/CT offers potential to detect AL deposits in The primary aim this study was determine distribution and frequency various organs subjects using PET/CT. Methods: This prospective included 40 biopsy-proven including active (n = 30) or hematologic remission for more than 1 y 10). All...
Borderline Resectable and Locally Advanced Pancreatic Cancer: FDG PET/MRI CT Tumor Metrics for Assessment of Pathologic Response to Neoadjuvant Therapy Prediction SurvivalAnanya Panda, MD1, Ishan Garg, MBBS1, Mark J. Truty, MD2, Timothy L. Kline, PhD1, Matthew P. Johnson, MS3, Eric C. Ehman, Garima Suman, Deema A. Anaam, Bradley Kemp, Geoffrey B. MD, Thorvardur R. Halfdanarson, MD4, Sudhakar K. Venkatesh, Jeff Fidler, MD1 Ajit H. Goenka, MD1Audio Available | Share
Magnetic resonance elastography (MRE) is a phase-contrast technique that can spatially map shear stiffness within tissue-like materials. To date, however, MRE of the lung has been too technically challenging-primarily because signal-to-noise ratio (SNR) limitations and phase instability. We describe an approach in which wave propagation not encoded into MR signal material, but rather from arising polarized noble gas encapsulated within. determine feasibility approach, three experiments were...
Magnetic resonance elastography (MRE) has been demonstrated to have potential as a clinical tool for assessing the stiffness of tissue in vivo. An essential step MRE is generation acoustic mechanical waves within via coupled driver. Motivated by an increasing volume human imaging trials using MRE, objectives this study were audit vibration amplitude exposure our IRB-approved studies, compare these values conservative regulatory standard vibrational and evaluate applicability implications...
Prostate-specific membrane antigen (PSMA) is a validated target for molecular diagnostics and targeted radionuclide therapy. Our purpose was to evaluate PSMA expression in hepatocellular carcinoma (HCC), cholangiocarcinoma (CCA), hepatic adenoma (HCA); investigate the genetic pathways HCC associated with expression; detection rate
The purpose of this study was to investigate the combined potential 80-kV CT and noise reduction using a projection space denoising algorithm reduce radiation dose or improve image quality hepatic CT.Twenty patients with 56 liver lesions underwent dual-energy (80 140 kV) contrast-enhanced CT. Low-dose 80-kV-only images (comprising 26-54% total dose), low-dose (routine sharper reconstruction kernel), full-dose mixed-kilovoltage were evaluated by three radiologists for lesion conspicuity,...
Objective To develop dual-energy computed tomography methods for identification of hyperenhancing, hypoenhancing, and nonenhancing small-bowel pathologies. Methods Small-bowel phantoms simulating varying patient sizes polyp types (hyperenhancing, nonenhancing) contained bismuth suspension in the lumen. Dual-energy CT was performed at 80/140 kV 100/140 kV. Computed tomographic number ratios (CT numbers low/high kilovoltage) were calculated. Two radiologists evaluated detection conspicuity...
To evaluate the effect of hepatic steatosis on LI-RADS® major features at MRI in patients with non-alcoholic fatty liver disease (NAFLD)-associated hepatocellular carcinoma (HCC).HCC and parenchyma from 48 consecutive NAFLD histology proven HCC (mean ± SD; 4.5 3.4 cm) were independently reviewed by three radiologists. Inter-rater agreement was determined prevalence/bias-adjusted kappa. Hepatic fat signal fraction (FS%) calculated. compared FS% using logistic regression analysis histologic...
The purpose of this prospective study was to determine the correct localization rate (CLR) <sup>18</sup>F-fluorocholine PET for detection parathyroid adenomas in comparison <sup>99m</sup>Tc-sestamibi imaging. <b>Methods:</b> This a single-arm trial. Ninety-eight patients with biochemical evidence primary hyperparathyroidism were imaged before parathyroidectomy using PET/MRI. imaging performed separately from evaluated comparison. endpoint CLR on patient level. Each interpreted by 3 masked...