A5044047742- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer, Hypoxia, and Metabolism
- Colorectal Cancer Treatments and Studies
- Cancer Research and Treatments
- Adrenal and Paraganglionic Tumors
- Advanced Radiotherapy Techniques
- Gastric Cancer Management and Outcomes
- Pancreatic and Hepatic Oncology Research
- Management of metastatic bone disease
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Telomeres, Telomerase, and Senescence
- Colorectal and Anal Carcinomas
- Neuroblastoma Research and Treatments
- Radiomics and Machine Learning in Medical Imaging
- RNA modifications and cancer
- Colorectal Cancer Surgical Treatments
- Lung Cancer Diagnosis and Treatment
- Radiation Therapy and Dosimetry
- Hormonal Regulation and Hypertension
- Ferroptosis and cancer prognosis
- Cancer Diagnosis and Treatment
- Lung Cancer Research Studies
- Advanced X-ray and CT Imaging
- Immune Cell Function and Interaction
- Renal cell carcinoma treatment
Soochow University
2014-2024
Rede de Química e Tecnologia
2019
Zhongnan Hospital of Wuhan University
2013-2014
Wuhan University
2013-2014
Purpose: This phase II/III, non-randomized clinical trial aimed to determine the efficacy and safety of combination radiofrequency ablation (RFA) cytokine-induced killer (CIK) cells transfusion for patients with colorectal liver metastases (CRLMs). Experimental Design: A total 60 eligible CRLMs were enrolled divided into Group (RFA alone, n = 30) B plus CIK, 30), following enzyme-linked immunosorbent spot assay was performed in 8 CEA > 50 ng/mL pre-RFA 7 days post-RFA CIK treatment,...
Purpose: Microwave ablation (MWA) is a recently developed thermal technique that has been used for the treatment of different types tumours. In present study, we retrospectively evaluated safety and efficacy CT-guided percutaneous MWA colorectal cancer (CRC) pulmonary metastases.Materials methods: From June 2010 to 2015, 48 unresectable lesions in 32 patients with CRC metastases were subjected MWA. Imaging follow-up was contrast-enhanced CT 18F-fluorodeoxyglucose (FDG) positron emission...
To evaluate the efficacy of hepatic artery infusion (HAI) floxuridine (FUDR) in combination with systemic chemotherapy patients pancreatic cancer liver metastases (PCLM).We retrospectively collected clinical data 347 PCLM who underwent first-line at two Chinese centers between 2012 and 2019. Propensity score matching without HAI was performed to compensate for differences baseline characteristics. Objective response rate (ORR) overall survival (OS) groups were compared. pump functionality...
This study aimed to compare the efficacy and safety of HAI fluoropyrimidine (FUDR)/capecitabine or single capecitabine as first-line treatment for elderly patients with unresectable colorectal liver metastases (CLMs). Fifty-one liver-only CLMs were eligible enrollment. Patients divided into FUDR /capecitabine group randomly. The primary endpoint was median survival time (MST), defined from date catheter implantation death last follow-up. secondary objective antitumor response adverse events....
Background: When liver metastasis in patients with breast cancer is diagnosed, treatment generally palliative and usually consists of systemic therapies only. This study aimed to evaluate the efficacy safety hepatic arterial infusion (HAI) combined chemotherapy carcinoma metastases (BCLM). Methods: From January 2012 December 2019, HAI catheter systems were implanted under guide digital subtract angiography (DSA) 19 BCLM. All received gemcitabine plus floxuridine (FUDR). The overall response...
Abstract Background Superficial soft tissue metastasis (S-STM) of malignant tumors is uncommon and often brings great pain to patients. However, current treatment options are limited. The purpose this study was explore the clinical efficacy prognostic factors CT-guided radioactive iodine-125 ( 125 I) seed implantation (RISI) for S-STM. Methods We retrospectively evaluated 132 patients with S-STM who received RISI between June 2010 July 2022. Local tumor progression-free survival (ltPFS),...
Abstract Rationale: Vulvar metastasis of colorectal cancer (CRC) and acquired resistance to cetuximab is a very rare phenomenon. To our knowledge, few cases have been reported in the English literatures. Patient concerns: A 55-year-old woman was diagnosed as adenocarcinoma rectum primary tumor detected be Kirsten-RAS (KRAS) wild type. Diagnoses: The patient with rectal by colonoscopy. Positron emission tomography/computed tomography (PET-CT) revealed multiple lymph node bone metastases....
Liver metastases in patients with gastric cancer often indicate poor prognosis. Once liver are extensive, it is difficult to achieve disease control by using systemic chemotherapy alone. The purpose of this study was evaluate the effect and safety hepatic arterial infusion (HAI) combined on extensive from cancer.Between 2012 2019, 21 (LMGC) were enrolled our study. identified as unresectable a major factor affecting prognosis mainly based size number intrahepatic lesions. All received S-1...
Pheochromocytoma with lung metastases is rare in clinics, and the prognosis of metastatic pheochromocytoma generally poor. In this case, a 57-year-old woman who presented hypertension palpitations was diagnosed left adrenal metastasis 2010. The patient received adrenalectomy for 10 years ago, but pulmonary lesions had significant progression 7 ago. treated iodine-125 (125I) seed implantation lesions. All 5 achieved partial response 6 months later, further shrank 1 year were successfully...
Objective To observe the changes of telomere length and radiosensitivity U2OS cells after its TPP1 gene is suppressed by small interfering RNA (siRNA).Methods According to coding sequence mRNA,the interference TPP1-siRNA was designed.The were transfected with lipofectamine.The expression detected RT-PCR Western blot,the measured Real-time PCR.The cell apoptosis analyzed flow cytometry,and determined clone formation assay.Results The inhibition rates protein expressions in group (65.70 ±...