A5030963866- Anesthesia and Pain Management
- Airway Management and Intubation Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Sedative Agents
- Tracheal and airway disorders
- Respiratory Support and Mechanisms
- Hemodynamic Monitoring and Therapy
- Pediatric Pain Management Techniques
- Traumatic Brain Injury and Neurovascular Disturbances
- Nausea and vomiting management
- Intensive Care Unit Cognitive Disorders
- Neonatal Respiratory Health Research
- Spine and Intervertebral Disc Pathology
- Sepsis Diagnosis and Treatment
- Peripheral Nerve Disorders
- Renal function and acid-base balance
- Liver Disease and Transplantation
- Obstructive Sleep Apnea Research
- Shoulder Injury and Treatment
- Uterine Myomas and Treatments
- Pain Management and Opioid Use
- Nerve Injury and Rehabilitation
- Cerebrovascular and Carotid Artery Diseases
- Abdominal Surgery and Complications
- Cardiac Arrest and Resuscitation
Centre Hospitalier Universitaire de Tours
2015-2025
Thion Medical (France)
2001-2024
Université de Tours
2012-2023
Research Network (United States)
2022
Hôpital Bretonneau
2001-2021
Imation (United States)
2002-2014
Groupe d'Oncologie Radiothérapie Tête et Cou
2005-2014
Centre Val de Loire
2013
Hôpital Pasteur
2013
Inserm
2012
Ketamine has been shown to have a morphine-sparing effect soon after surgery. Nevertheless, whether this still exists being combined with nonsteroidal antiinflammatory drugs and acetaminophen, ketamine can decrease chronic pain nononcologic surgery remain unclear. Thus, we designed study assess ketamine's on acute postoperative when multimodal analgesia total hip arthroplasty (THA).Patients scheduled for primary THA using standardized general anesthesia were randomized. They received IV...
In Brief BACKGROUND: healthy patients, the narrowest diameter of subglottic upper airway is width air-column at level cricoid cartilage. This governs selection endotracheal tube size, as excessive may damage tracheal mucosa leading to postextubation stridor or stenosis. Unfortunately, selecting size based on height, weight, age does not reliably lead proper tube. The knowledge diameter, especially using a bedside noninvasive tool, could therefore be helpful in anesthesia and intensive care....
Background It is speculated that the anesthetic strategy during endovascular therapy for stroke may have an impact on outcome of patients. The authors hypothesized conscious sedation associated with a better functional 3 months after treatment compared general anesthesia. Methods In this single-blind, randomized trial, patients received either standardized anesthesia or sedation. Blood pressure control was also in both groups. primary measure modified Rankin score less than equal to 2 (0 =...
Abstract Background After cardiac surgery, post-operative delirium (PoD) is acknowledged to have a significant negative impact on patient outcome. To date, there no valuable and specific treatment for PoD. Critically ill patients often suffer from poor sleep condition. There an association between quality after surgery. This study aimed establish whether promoting using overnight infusion of dexmedetomidine reduces the incidence Methods Randomized, pragmatic, multicentre, double-blind,...
The present study aimed to examine the prevalence of burnout, levels life satisfaction and job in anaesthetists France. A cross-sectional was conducted among 193 from eight French public hospitals. results indicated low emotional exhaustion depersonalization scores, but high reduced accomplishment. also revealed differences between subgroups: physician reported higher accomplishment than nurse anaesthetists, female junior dissatisfaction male senior anaesthetists. implications reduce burnout...
To provide French guidelines about "Airway management during paediatric anaesthesia".A consensus committee of 17 experts from the Society Anaesthesia and Intensive Care Medicine (Société Française d'Anesthésie-Réanimation, SFAR) Association speaking anaesthesiologists intensivists (Association Des Anesthésistes Réanimateurs Pédiatriques d'Expression Francophone, ADARPEF) was convened. The entire process conducted independently any industry funding. authors followed principles Grading...
Accurate assessment of consciousness during general anesthesia is crucial for optimizing anesthetic dosage and patient safety. Current electroencephalogram-based monitoring devices can be inaccurate or unreliable in specific surgical contexts (e.g. cephalic procedures). This study investigated the feasibility using electrocardiogram (ECG) features machine learning to differentiate between awake anesthetized states. A cohort 48 patients undergoing surgery under at Tours hospital was...
Although prior studies have shown that smoke inhalation causes lung endothelial injury and formation of pulmonary edema, there is no information about the effect on function alveolar epithelial barrier. Therefore, primary objective this study was to determine smoke-induced barrier in a rabbit experimental model. The second investigate whether pretreatment with monoclonal anti–interleukin (IL)-8 antibody prevented after inhalation. Anesthetized rabbits were tracheotomized insufflated cooled...
In pediatric practice, complications due to the laryngeal mask airway (LMA) have been studied with size 2 LMA, but not 1 LMA. We, therefore, compared prospectively induced by LMA and in 141 children aged 21 days 11 yr. Intraoperative lowest SpO2 values after removal of were recorded. The following recorded: cough, laryngospasm, bronchospasm, apnea, obstruction. 14 patients group 26 group, pharyngolaryngeal structures checked fiberoptic examination. number attempts, complications,...
Background and objective It is not known whether anaesthetic practices for ASA I parturients undergoing scheduled caesarean delivery have changed since the last (1996) survey how reflect current recommendations. Methods A 26-item questionnaire (organization of maternity unit, preoperative evaluation, technical aspects describing regional or general anaesthesia, oxytocic antibiotic drugs, postoperative analgesia) was distributed to all French obstetric units (excluding overseas). Results The...
Postoperative analgesia via continuous perineural infusion of local anesthetics compares favorably with systemic analgesia. Elastomeric pumps increase patient satisfaction compared electronic models. In in vitro investigations, infusions remained within 15% their designated set rates. We assessed vivo the rate elastomeric regional after orthopedic surgery.All consecutive were retrospectively studied during a 10-mo period. Perineural catheters inserted preoperatively and connected...
There are no guidelines for the anaesthetic management of caesarean section in women with long QT syndrome; description myocardial ventricular repolarisation healthy during delivery could be a first step. The aim this study was to describe modification interval, corrected heart rate, and interval between peak end T-wave (Tpeak-Tend interval) under spinal anaesthesia. We studied 40 patients scheduled Patients were randomly assigned receive either ephedrine or phenylephrine prevent...
In reference textbooks describing axillary block, the ulnar, radial, and median nerves are located in a common sheath surrounding artery. contrast, musculocutaneous nerve is described as lying outside this coracobrachialis muscle. recent case report of ultrasound-guided was joined to Our study evaluated prevalence atypical localizations during block.All patients undergoing block were included from December 2006 2008. Before needle insertion, musculocutaneous, median, radial localized using...
Point-of-care testing (POCT) systems enable a wide range of tests to be rapidly performed at the bedside and have attracted increasing interest in intensive care unit (ICU). However, previous studies comparing concordance POCT with central laboratory reported divergent findings. Most on reliability focused analyzer performance rather than preanalytical phase. The aim this study was assess results provided by point-of-care analyzers according organization units process. In three adult...
In Brief A limitation of preoperative autologous blood donation (PABD) in nonanemics and the use recombinant human erythropoietin (EPO) anemics (baseline hematocrit [Hct] ≤ 39%) could be an efficient approach cost-benefit ratio transfusion during primary total hip (THA) or knee (TKA) arthroplasties. We evaluated consequences on rates costs two different applications a policy based personal requirements THA TKA. This quality assuranceobservationalstudycomparedtwoprospective successive time...
Summary The laryngeal mask airway (LMA) must be inserted during deep anaesthesia. There are no guidelines concerning the removal of LMA, i.e., in awake or anaesthetized patients. aim this randomized prospective study was to compare incidence respiratory complications after LMA paediatric Sixty children (ASA PS I II), ranging from 4 months 12 years age, were studied. In patients breathing spontaneously, anaesthesia induced and maintained with nitrous oxide, oxygen halothane. Patients randomly...
Summary Background: Preoxygenation is recommended in pediatric anesthesia but it has been poorly assessed. Fractional expired oxygen concentration (F ET O 2 ) a preoxygenation monitor. The aim of this prospective study children was to compare three techniques by the measurement F 2. Methods: Twenty (6–15 years) were included. measured with child supine position, holding facemask. value after 3 min calm breathing room air (baseline) and during performed random order: tidal volume using an...
In France, the program of controlled donation after circulatory death (cDCD) was established with routine use in situ normothermic regional perfusion (NRP). There is currently no consensus on its optimal duration. The purpose to assess impact NRP duration liver graft function and biliary outcomes. One-hundred fifty-six recipients from NRP-cDCD donors six French centers between 2015 2019 were included. Primary endpoint assessed by early allograft dysfunction (EAD, according Olthoff's...
We performed a prospective descriptive study over 5-month period to determine the incidence of postoperative nausea and vomiting (PONV) during first 24 h following elective ambulatory paediatric surgery, excluding head neck procedures.Four hundred seven patients, aged 15 days 16 years, were analysed prospectively.The PONV was 9.4%, occurring most frequently 3 after anaesthesia in hospital but rarely journey home. It associated with age, previous history PONV, tracheal intubation or use...