A5074592383- Hepatitis B Virus Studies
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Viral gastroenteritis research and epidemiology
- Hepatitis Viruses Studies and Epidemiology
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Animal Virus Infections Studies
- Vibrio bacteria research studies
- COVID-19 epidemiological studies
- Virus-based gene therapy research
- Plant Virus Research Studies
- Viral Infections and Outbreaks Research
- Bacillus and Francisella bacterial research
- Mosquito-borne diseases and control
- COVID-19 Impact on Reproduction
- Bacteriophages and microbial interactions
- COVID-19 and Mental Health
- Full-Duplex Wireless Communications
- Molecular Biology Techniques and Applications
- Viral Infections and Vectors
- T-cell and Retrovirus Studies
- Polyomavirus and related diseases
- HIV/AIDS drug development and treatment
- HIV Research and Treatment
High Institute for Education and Research in Transfusion Medicine
2014-2025
Rega Institute for Medical Research
2014-2025
KU Leuven
2015-2025
Shiraz University of Medical Sciences
2019-2025
Shahid Beheshti University of Medical Sciences
2022
Iranian Legal Medicine Organization
2007-2010
This study aimed to reveal the 30-year dynamics of hepatitis B virus (HBV) and C (HCV) disease burden in China from 1990-2019.HBV/HCV data were retrieved Global Burden Disease database. Joinpoint regression was used examine temporal trends. Age-period-cohort models applied evaluate effects patient age, period, cohort on HBV/HCV-associated mortality incidences.A dramatic decrease HBV found 1990-2019, but HCV has remained stable since 2000. Patient exerted a significant effect diseases...
Patients with diabetes are at increased risk of HBV infection; however, the effects infection and anti-HBV therapy on management type 1 (T1D), 2 (T2D), latent autoimmune in adults (LADA) remain unclear. From 2016 to 2023, we recruited a multicenter cohort 355 HBV-infected inpatients, including 136 T1D, 140 T2D, 79 LADA. The control group included 525 HBV-uninfected comparing 171 204 T2D 150 We employed propensity-score matching between cases controls minimize confounding effects. Hemoglobin...
Understanding the dispersal patterns of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) lineages is crucial to public health decision-making, especially in countries with limited access viral genomic sequencing. This study provides a comprehensive epidemiological and phylodynamic perspective on SARS-CoV-2 lineage Iran from February 2020 July 2022. We explored epidemiology combining 1281 genome sequences spatial data phylogeographic framework. Our analyses shed light multiple...
<h3>Background and aims:</h3> Anti-α4 integrin therapy with natalizumab is efficacious in refractory Crohn's disease multiple sclerosis, but carries an estimated 1/1000 risk of progressive multifocal leukoencephalopathy (PML) caused by reactivation latent JC virus infection. Athough anti-α4 therapies are likely to be introduced the clinic, screening for PML has not been developed. <h3>Methods:</h3> We prospectively collected urine, serum, plasma buffy coats from 125 patients disease, 100...
As an important anti-HBV drug, pegylated interferon α (PegIFNα) offers promising clinical efficacy, but biomarkers that accurately forecast treatment responses are yet to be elucidated. Here, we evaluated whether HBV RNA could act as early monitor of responses.
BackgroundThe role of the microbiome in liver transplantation (LT) outcome has received a growing interest past decades. In contrast to bacteria, endogenous viral communities, known as virome, is poorly described. Here, we applied metagenomic approach study dynamic evolution circulating viruses plasma LT recipients and its effect on clinical course patients.MethodsPatients chronically infected with hepatitis B virus (HBV) that due endstage disease were included this study. Longitudinal...
Abstract Cytokine storms, which result from an abrupt, acute surge in the circulating levels of different pro-inflammatory cytokines, are one complications associated with severe respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. This study aimed to assess effect exosomes on release cytokines patients disease 2019 (COVID-19) and compare it a control group. The evaluated this were TNF-α, IL-6, IL-17, IFN-γ. compared these peripheral blood mononuclear cells (PBMCs) five COVID-19...
Molecular evolutionary patterns of 62 HBV full-length genomes obtained from Belgian patients were characterized. Phylogenetic analysis revealed diverse subgenotypes including A2 and A6 (46.8%), D1-D4 (38.8%), E (9.7%), C1 (1.6%), B2 (1.6%). The study population consisted with different ethnic origin (Caucasian, Turkish, Asian, Arab, African). One D/C recombinant isolate was identified, which encoded subtype adw2. An subgenotype D4 an aberrant ayw4 detected. Although none the genotypes...
Abstract The genetic diversity of the HBV S gene has a significant impact on prophylaxis and treatment hepatitis B infection. effect selective pressure this alteration not yet been studied in Iranian blood donors. To explore evolution to analyze effects patterns surface antigen (HBsAg) mutations screening assays, 358 donors diagnosed as asymptomatic carriers were enrolled nationwide study. Large partial genes amplified sequenced. (sub) genotypes synonymous nonsynonymous investigated....
Objective This study aims to reveal epidemiological features and trends of liver cancer (LC) in China. Methods We retrieved data from the Global Burden Disease database 2019. Joinpoint regression was used examine temporal trend LC. Future LC were estimated using Nordpred. Results The incidence, mortality, disability-standardized life year (DALY) rate declined China 1990 Among &gt;210,000 cases 2019, incidences nearly 3.15 times higher males than females. LC-associated deaths mostly found...
Abstract Hepatitis B virus (HBV) and human immunodeficiency (HIV) have similar transmission routes, implying that patients infected with HIV are at particular risk for HBV infection. Patients who co‐infected progress more rapidly to end‐stage liver disease different genotypes may a distinct impact on progression. One hundred ninety‐one anti‐HBc‐positive sera from Belgian were collected during 1998–2008. Full‐length genomes as well large S or partial genes amplified their molecular...
Chronic hepatitis C virus infection and its sequela are major health problems facing the Egyptian community. The high prevalence spread rates of disease require serious actions to stop or decrease these rates. Determination HCV genotypes subgenotypes adds significant knowledge about epidemiology disease, provides an added value in decision making process what strategy follow therapy response expect. molecular genetic variability variants circulating Egypt still need further analysis.The...