A5075100324- Virus-based gene therapy research
- Viral Infections and Vectors
- Vector-borne infectious diseases
- Animal Virus Infections Studies
- Rabies epidemiology and control
- Microbial infections and disease research
- Yersinia bacterium, plague, ectoparasites research
- Viral gastroenteritis research and epidemiology
- Animal Disease Management and Epidemiology
- Herpesvirus Infections and Treatments
- Virology and Viral Diseases
- Vector-Borne Animal Diseases
- Aquaculture disease management and microbiota
- Parvovirus B19 Infection Studies
- Insect and Pesticide Research
- Veterinary Oncology Research
- Antimicrobial agents and applications
- Insect symbiosis and bacterial influences
- Antimicrobial Resistance in Staphylococcus
- Genomics and Phylogenetic Studies
- Streptococcal Infections and Treatments
- Bacterial biofilms and quorum sensing
- Mosquito-borne diseases and control
- Bat Biology and Ecology Studies
- Pharmaceutical and Antibiotic Environmental Impacts
Leipzig University
2014-2022
Institut für Mikrobiologie der Bundeswehr
2010-2018
German Center for Infection Research
2018
Institute of Medical Microbiology and Hygiene
2017
Leibniz Association
2005-2014
Bundeswehr Medical Service Academy
2012-2014
Universität der Bundeswehr München
2010-2012
Bundeswehr
2012
Leibniz Institute for Zoo and Wildlife Research
2003-2010
Leibniz Institute for Neurobiology
2008
Re-vaccinations against canine distemper virus (CDV) are commonly performed in 3-year intervals. The study's aims were to determine anti-CDV antibodies healthy adult dogs within 28 days of vaccination CDV, and evaluate factors associated with the presence pre-vaccination antibody response vaccination. Ninety-seven dogs, not vaccinated 1 year before enrollment, a modified live CDV vaccine. A measurement was (day 0), on day 7, after by neutralization. defined as ≥4-fold titer increase 28....
Background Bats receive increasing attention in infectious disease studies, because of their well recognized status as reservoir species for various agents. This is even more important, bats with capability long distance dispersal and complex social structures are unique the way microbes could be spread by these mammalian species. Nevertheless, infection studies predominantly limited to identification specific pathogens presenting a potential health threat humans. But impact agents on...
Complementary DNA (cDNA) clones encoding the heavy chain of heterodimeric human membrane glycoprotein 4F2 have been isolated by immunoscreening a lambda gt11 expression library. The identity these has confirmed hybridization to RNA and prepared from mouse L-cell transfectants, which were produced whole cell gene transfer selected for cell-surface chain. sequence analysis suggests that heavy-chain cDNAs encode an approximately 526-amino acid type II glycoprotein, is composed large C-terminal...
We tested 55 deceased vespertilionid bats of 12 species from southern Germany for virus infections. A new adenovirus was isolated tissue samples 2 Pipistrellus pipistrellus bats, which represents the only chiropteran isolate found in Europe besides lyssavirus (rabies virus). Evidence transmission between bats.
The emergence of important viral diseases and their potential threat to humans has increased the interest in bats as reservoir species. Whereas majority studies determined occurrence specific zoonotic agents chiropteran species, little is known about actual bat pathogens impacts disease on mortality. Combined pathological microbiological investigations free-ranging are sparse often limited by small sample sizes. In present study 500 deceased 19 European species (family Vespertilionidae) were...
From 1997-99 European brown hare (Lepus europaeus) population densities were estimated by spotlight surveys within different areas in Schleswig-Holstein, Germany. These showed a wide variation local densities. In addition, red fox (Vulpes vulpes) 1997 of dens and litters. Sera 321 hares (shot between 1998-2000) from four study examined for antibodies against syndrome virus (EBHSV) enzyme linked immunosorbent assay (ELISA), Yersinia spp. (n = 299) Francisella tularensis western blotting,...
Antibiotics are mandatory additives in semen extenders to control bacterial contamination. The worldwide increase resistance conventional antibiotics requires the search for alternatives not only animal artificial insemination industries, but also veterinary and human medicine. Cationic antimicrobial peptides of interest as a novel class boar preservation. present study investigated effects two synthetic cyclic hexapeptides (c-WFW, c-WWW) helical magainin II amide derivative (MK5E) on sperm...
High amounts of aerial pollutants like dust and microorganisms can pose serious health hazards to animals humans. The aim the current study therefore was, assess efficiency UVC irradiation combined air filtration in reducing airborne at laboratory scale. In a second part, UVC-combined recirculating module (UVC module) was implemented small animal facility order its improvement quality with regard bacteria dust. Tests scale were performed using aerosols Staphylococcus (S.) aureus,...
A taxonomic study was performed on 13 bacterial strains isolated from preputial swabs of European bison ( Bison bonasus ) bulls suffering balanoposthitis. The isolates were Gram-positive, non-motile, facultatively anaerobic, diphtheroid-shaped cells. Based biochemical profiles and BOX-PCR-generated genomic fingerprints, the grouped into two clusters represented by four nine strains, respectively. Strains 1(W3/01) T 2(W106/04) , selected as representatives clusters, shared 97·2 % 16S rRNA...
During an outbreak of respiratory disease in captive chimpanzees (Pan troglodytes), gorillas (Gorilla gorilla), Bornean orangutans (Pongo pygmaeus), and red-capped mangabeys (Cercocebus torquatus) also staff members showed non-specific upper signs. One infant female chimpanzee with severe symptoms died despite immediate medical treatment was submitted for necropsy.Routine post mortem, histological bacteriological examinations were conducted. Additionally lung tissue samples form the swab...
Various semen extender formulas are in use to maintain sperm longevity and quality whilst acting against bacterial contamination liquid preservation. Aminoglycosides commonly supplemented aid the control of bacteria. As resistance is increasing worldwide, antimicrobial peptides (AMPs) received lively interest as alternatives overcome multi-drug resistant We investigated, whether synthetic cationic AMPs might be a suitable alternative for conventional antibiotics boar The antibacterial...
Biosecurity is defined as the implementation of measures that reduce risk disease agents being introduced and/or spread. For pig production, several these are routinely implemented (e.g. cleaning, disinfection, segregation). However, air a potential vector pathogens has long been disregarded. Filters for incoming and recirculating were installed into an already existing ventilation plant at fattening piggery (3,840 pigs maximum) in Saxony, Germany. Over period three consecutive periods, we...
Microbes interfere with the olfactory communication of animals by degrading chemical signals or adding volatile metabolites. We report on composition and diversity microflora in a sexually selected scent organ, wing sacs Saccopteryx bilineata, which are used males for courting females. Wing lack any glandular tissues. Instead, clean refill their each day genital gular secretions. Females have only nonfunctional rudiment this organ. isolated total 40 microbial species moderate overlap between...
Inactivated whole-virus vaccines against porcine parvovirus (PPV) can prevent disease but not infection and virus shedding after heterologous challenge. Here, we showed that the same is true for a homologous Pregnant sows were vaccinated with an experimental inactivated vaccine based on PPV strain 27a. They challenged day 40 of gestation virulent PPV-27a from which was prepared (homologous challenge). On 90 gestation, fetuses protected disease, while non-vaccinated (control group) exhibited...
According to prior studies, between 25.0% and 92.8% of adult cats have antibodies against feline panleukopenia virus (FPV) thus are likely protected FPV infection. It is, however, unknown how healthy with different antibody titres react vaccination in the field. Therefore, aim study was measure within a period 28 days after evaluate factors that associated lack adequate response vaccination.