A5055347969- Reconstructive Surgery and Microvascular Techniques
- Orthopedic Surgery and Rehabilitation
- Bone fractures and treatments
- Surgical site infection prevention
- Wound Healing and Treatments
- Surgical Sutures and Adhesives
- Elbow and Forearm Trauma Treatment
- Body Contouring and Surgery
- Reconstructive Facial Surgery Techniques
- Orthopedic Infections and Treatments
- Shoulder Injury and Treatment
- Breast Implant and Reconstruction
- Peripheral Nerve Disorders
- Anatomy and Medical Technology
- Musculoskeletal synovial abnormalities and treatments
- Radiation Detection and Scintillator Technologies
- Cancer Diagnosis and Treatment
- Diversity and Career in Medicine
- Nuclear Physics and Applications
- Burn Injury Management and Outcomes
- Organ and Tissue Transplantation Research
- Lymphatic System and Diseases
- Diabetic Foot Ulcer Assessment and Management
- Medical Practices and Rehabilitation
- Nonmelanoma Skin Cancer Studies
TU Dresden
2018-2025
University Hospital Carl Gustav Carus
2017-2025
Klinik und Poliklinik für Psychotherapie und Psychosomatik
2020-2024
National Center for Tumor Diseases
2024
Klinikum St. Georg
2014-2018
Friedrich-Alexander-Universität Erlangen-Nürnberg
2008-2014
Universitätsklinikum Erlangen
2007-2013
Adrian College
2011-2012
Heidelberg University
2004-2011
University Hospital Heidelberg
2011
Background —We studied the effects of angiotensin II (Ang II) and diastolic overstretch on induction cardiac growth in isometrically contracting muscle preparations from human right atria left ventricles. We used gene expression brain natriuretic peptide (BNP) as a molecular marker hypertrophy. Methods Results —Northern blot analysis was performed atrial preparations, which were either incubated 10 −6 mol/L Ang for 45 minutes or diastolically stretched to 120% optimum length. Similar...
Since the implementation and use of silicone implants in breast surgery risks are published discussed. Especially, incidence late implant rupture its potential risk to induce local siliconomas still under discussion not sufficiently evaluated. So far literature data offer no information intrapulmonal or peripheral located cutaneous because systemic migration after augmentation. In light silicones checkered history, given large growing number women who choose undergo augmentation each year,...
Abstract Bone tissue engineering approaches increasingly focus on the use of mesenchymal stem cells (MSC). In most animal transplantation models MSC are isolated and expanded before auto cell which might be critical for clinical application in future. Hence this study compares potential directly auto‐transplanted versus vitro with or without bone morphogenetic protein‐2 (BMP‐2) to induce formation a large volume ceramic substitute sheep model. were from marrow aspirates characterized using...
Electrical injuries represent life-threatening emergencies. Evidence on differences between high (HVI) and low voltage (LVI) regarding characteristics at presentation, rhabdomyolysis markers, surgical intensive burn care outcomes is scarce.Consecutive patients admitted to two centers for electrical over an 18-year period (1998-2015) were evaluated. Analysis included comparisons of HVI vs. LVI demographic data, diagnostic treatment specific variables, particularly serum creatinine kinase (CK)...
Topical negative pressure wound therapy (TNPWT) is one of the most frequently used techniques in treatment. But some underlying mechanisms still remain unclear. One possible explanation an improved microcirculation by TNPWT.This study investigated influence TNPWT on intact skin real-time.In healthy individuals, we performed a combined tissue - laser/photo spectrometry technique to monitor changes 4 different parameters real-time: The local blood flow, capillary-venous oxygen saturation, flow...
Objective: Severe soft tissue damage with destruction of the dermis requires plastic reconstructive treatment. For multimorbid patients or unable to undergo major surgery, use dermal substitutes, such as a collagen-elastin matrix (CEM) split-thickness skin graft (STSG), instead local free flap may be valid and easy treatment option. We aimed investigate compare outcomes rate successful defect reconstruction using CEM plus STSG, either one-step approach (simultaneous STSG) two-step (CEM...
Mid regional pro-adrenomedullin (MR-proADM) has been used as a marker of sepsis, but its dynamics and role in burn injury setting not tested. In prospective observational study, we included 42 consecutive patients with >15% TBSA. Daily blood specimens collected over the initial 20 days treatment were submitted for laboratory analysis MR-proADM procalcitonin (PCT) via immunoluminometric sandwich assay (Kryptor, BRAHMS, Berlin, Germany). an absence increase PCT levels was noted post-burn...
Background and aims: This study on healthy test subjects intends to show whether one-off Low-Level Laser Therapy (LLLT) has an instant effect the perfusion or oxygenation of skin tissue. These possible effects may have influence accelerated wound healing which is often observed after application LLLT, in addition usual postulated LLLT occur with a time delay normally.Study design/materials methods: The was carried out double-blind placebo-controlled two batches testing. received defined area...
Abstract Preventing ischemia-related cell damage is a priority when preserving tissue for transplantation. Perfusion protocols have been established variety of applications and proven to be superior procedures used in clinical routine. Extracorporeal perfusion muscle though cumbersome highly desirable since it susceptible damage. To show the efficacy different external field stimulation can immediately visualize improvement or deterioration during active running protocols. This method has...
Three-dimensional (3D) technology has become a standard manufacturing element in many industries and gained significant interest plastic surgery. The 3D scans are widely used for patient communication, virtual surgery planning, intraoperative tool manufacturing, providing more comprehensive view of procedures their outcomes compared with 2D visualization.
Background/Objective: With the rapid advancement in surgical technologies, new workflows for mandibular reconstruction are constantly being evaluated. Cutting guides extensively employed defining osteotomy planes but prone to errors during fabrication and positioning. A virtually defined plane drilling holes robotic surgery minimize potential sources of error yield highly accurate outcomes. Methods: Ten replicas were evaluated after cutting-guided saw robot-guided laser following with...
Background: With the rise of new 3D printers, assessing accuracy is crucial for obtaining best results in patient care. Previous studies have shown that highest achieved with SLS printing technology; however, SLA technology has made significant improvements recent years. Methods: In this study, a realistic anatomical model mandible and skull, cutting guide mandibular osteotomy, splint orthognathic surgery were replicated five times each using two different technologies: SLS. Results: The...
Abstract In later stages of vasculoangiogenesis a vascular network is going through metamorphosis for optimal perfusion and economy energy. this study we make quantitative approach to phenomena remodelling in bioartificial neovascular suggest variance calibre as parameter maturation. For study, 18 male Lewis rats were subjected the AV loop operation combination with hard porous biogenic matrix an isolation chamber. The animals allocated into three groups different explantation intervals set...