- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Protease and Inhibitor Mechanisms
- ECG Monitoring and Analysis
- Cardiovascular Effects of Exercise
- COVID-19 diagnosis using AI
- Cardiac electrophysiology and arrhythmias
- SARS-CoV-2 and COVID-19 Research
- Connective tissue disorders research
- COVID-19 Clinical Research Studies
- Cardiac Fibrosis and Remodeling
- Cardiac pacing and defibrillation studies
Ningbo First Hospital
2020-2024
Ningbo University
2024
Zhejiang University
2020
Atrial fibrosis occurs frequently with structural heart disease and is considered as a major cause of arrhythmia. Microarray-based profiling predicted the differential expression SPP1 in atrial fibrosis. Herein, we aimed to analyze role shRNA-mediated knockdown progression well downstream mechanism. In vivo model mice vitro HL-1 cell were developed by angiotensin II (Ang II) method, where was validated RT-qPCR. Gain- loss-of-function experiments performed Ang II-induced cells evaluate effect...
Importance The optimal strategy of combining left atrial appendage occlusion (LAAO) with catheter ablation (CA) in patients fibrillation (AF) during a single procedure remains unclear. Objective To determine the effects ablation-first vs occlusion-first strategies on long-term clinical outcomes among undergoing combined LAAO and CA procedure. Design, Setting, Participants prospective, multicenter COMBINATION randomized trial was conducted 14 high-volume centers China. Enrollment nonvalvular...
COVID-19 is a global pandemic. Currently, the predominant strain SARS-CoV-2 Omicron subvariant BA.2 in many countries. Understanding its infection characteristics can facilitate clinical management.This study aimed to characterize clinical, laboratory, and high-resolution computed tomography (HRCT) findings patients with mild or moderate from BA.2.We performed retrospective on infected between April 4th 17th, 2022. The characteristics, laboratory features, HRCT images were reviewed.A total...
Several algorithms based on 12-lead ECG measurements have been proposed to identify right ventricular outflow tract (RVOT) and left (LVOT) locations from which tachycardia (VT) frequent premature complex (PVC) originated. However, a clinical-grade artificial intelligence algorithm is not available yet, can automatically analyze characteristics of ECGs predict RVOT LVOT origins VT PVC. We randomly sampled training, validation, testing datasets 420 patients who underwent successful catheter...