Bing Leng

ORCID: 0000-0003-0788-6935
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About
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Research Areas
  • Intracranial Aneurysms: Treatment and Complications
  • Hippo pathway signaling and YAP/TAZ
  • Plant biochemistry and biosynthesis
  • Microbial Natural Products and Biosynthesis
  • IL-33, ST2, and ILC Pathways
  • Chromatography in Natural Products
  • Kruppel-like factors research
  • Cardiac Arrhythmias and Treatments
  • Polysaccharides and Plant Cell Walls
  • Plant-Microbe Interactions and Immunity
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Plant Pathogens and Fungal Diseases
  • Atrial Fibrillation Management and Outcomes
  • Cytokine Signaling Pathways and Interactions
  • Cardiac pacing and defibrillation studies
  • Neurosurgical Procedures and Complications
  • Cerebrovascular and Carotid Artery Diseases
  • Asthma and respiratory diseases
  • Vascular Malformations Diagnosis and Treatment
  • Cancer-related gene regulation

Huashan Hospital
2024

Fudan University
2024

Harbin Medical University
2021

Fourth Affiliated Hospital of Harbin Medical University
2021

Chinese Society for Plant Biology
2017

Chinese Society for Plant Pathology
2017

Importance The optimal strategy of combining left atrial appendage occlusion (LAAO) with catheter ablation (CA) in patients fibrillation (AF) during a single procedure remains unclear. Objective To determine the effects ablation-first vs occlusion-first strategies on long-term clinical outcomes among undergoing combined LAAO and CA procedure. Design, Setting, Participants prospective, multicenter COMBINATION randomized trial was conducted 14 high-volume centers China. Enrollment nonvalvular...

10.1001/jamanetworkopen.2024.45084 article EN cc-by-nc-nd JAMA Network Open 2024-11-15

Rationale: Severe asthma is a heterogeneous disease with multiple molecular mechanisms. Gene expression studies of asthmatic bronchial epithelial cells have provided biological insights and underscored possible pathological mechanisms; however, the basis in severe still poorly understood. Objective: The objective this study was to identify features uncover distinct phenotype. Methods: k-means clustering differentially expressed genes (DEGs) were performed 129 individuals Asthma Research...

10.3389/fgene.2021.765400 article EN cc-by Frontiers in Genetics 2021-10-25

Introduction: Intracranial aneurysm (IA) is a common vascular enlargement that occurs in the wall of cerebral vessels and frequently leads to fatal subarachnoid hemorrhage. PDZ LIM domain protein 1 (PDLIM1) cytoskeletal functions as platform for multiple complex formation. However, whether PDLIM involved pathogenesis IA remains poorly understood. Methods: Loss-of-function gain-of-function strategies were employed determine vitro roles PDLIM1 endothelial cells (VECs). A rat model was...

10.1177/1358863x231218210 article EN Vascular Medicine 2024-02-01

The optimal treatment strategy for elderly patients with ruptured intracranial aneurysms (IAs) remains controversial. We evaluated a national, multihospital database to compare the outcomes of aggressive and medical management those patients.

10.4103/neurol-india.neurol-india-d-23-00505 article EN Neurology India 2024-07-01

OBJECTIVE The authors report on a broad range of microsurgical procedures in which the suboccipital median technique was used to treat craniocervical junction arteriovenous fistulas. Their aim evaluate efficacy posteromedian approach and assess associated clinical outcomes. METHODS extracted information fistula site, manifestation, structural characteristics arterial venous vessels by retrospectively evaluating cases from neurointerventional database spanning 10 years. RESULTS In this study,...

10.3171/2024.7.jns2497 article EN Journal of neurosurgery 2024-12-01
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