A5015445079- Hepatocellular Carcinoma Treatment and Prognosis
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Colorectal Cancer Surgical Treatments
- Photodynamic Therapy Research Studies
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Nanoplatforms for cancer theranostics
- Renal cell carcinoma treatment
- Cancer, Hypoxia, and Metabolism
- Cancer, Lipids, and Metabolism
- Gastrointestinal Tumor Research and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Gallbladder and Bile Duct Disorders
- Developmental Biology and Gene Regulation
- Protein Degradation and Inhibitors
- Pancreatitis Pathology and Treatment
- Body Contouring and Surgery
- Nonmelanoma Skin Cancer Studies
- Colorectal and Anal Carcinomas
- Wnt/β-catenin signaling in development and cancer
- COVID-19 and healthcare impacts
- Neuroblastoma Research and Treatments
Second Xiangya Hospital of Central South University
2012-2023
Central South University
2012-2023
Creative Commons
2019
Chinese Academy of Medical Sciences & Peking Union Medical College
2012-2013
Underlying liver function is a major concern when applying surgical resection for hepatocellular carcinoma (HCC). We aimed to explore the capability of albumin-bilirubin (ALBI) grade predict post-hepatectomy failure (PHLF) and long-term survival after hepatectomy HCC patients with different Barcelona Clinic Liver Cancer (BCLC) stages.Between January 2010 December 2014, 338 who were treated enrolled. The predictive accuracy ALBI system PHLF across BCLC stages was examined.A total 26 (7.7%)...
Hepatocellular carcinoma (HCC) is the world's sixth most common malignant tumor and third cause of cancer death. Although great progress has been made in hepatectomy, it still associated with a certain degree risk post-hepatectomy liver failure (PHLF), which extends length hospital stay remains leading postoperative Studies have shown that assessment hepatic functional reserve before hepatectomy beneficial for reducing incidence PHLF.To assess value model end-stage disease (MELD) score...
Laparoscopic natural orifice specimen extraction surgery (NOSES) has been widely used in colorectal neoplasms. However, only a few studies have focused on robotic NOSES. This study compared the short-term clinical outcomes and long-term survival between NOSES conventional resection (CRR) groups.From March 2016 to October 2018, consecutive of 143 patients who underwent sigmoid rectal at Department Gastrointestinal Surgery, The Second Xiangya Hospital, Central South University, were considered...
To analyze the initial learning curve (LC) for robot-assisted pancreaticoduodenectomy (RAPD) and compare RAPD during LC with open (OPD) in terms of outcome. This study is a retrospective review patients who consecutively underwent OPD between October 2015 January 2020 our hospital. 41 consecutive cases 53 were enrolled review. Compared OPD, required significantly longer operative time (401.1 ± 127.5 vs. 230.8 44.5 min, P < 0.001) higher cost (194621 78342 121874 39973 CNY, 0.001). Moreover,...
Background and aims: The impact of portal hypertension (PH) on postoperative short-term outcomes long-term survival in hepatocellular carcinoma (HCC) patients has lately been discussed controversially. This study aimed to explore the influence PH HCC undergoing surgical resection.Methods: Patients hepatectomy for from 2010 2014 were enrolled. complications, posthepatectomy liver failure (PHLF) overall (OS) was evaluated.Results: A total 355 enrolled; 129 (36.3%) experienced complications 21...
Abstract Natural orifice specimen extraction surgery (NOSES) is especially suitable for colorectal surgery. Until now, most of the reports published were about laparoscopic NOSES, robotic NOSES are extremely rare. This study aims to explore safety and feasibility neoplasms. All patients underwent from March 2016 October 2019 in our hospital enrolled retrospective analysis. Clinicopathological data including patient characteristics, perioperative information pathological collected analyzed....
Abstract Although evidence for the application of an albumin-bilirubin (ALBI) grading system to assess liver function in hepatocellular carcinoma (HCC) is available, less known whether it can be applied determine prognosis single HCC with different tumor sizes. This study aimed address this gap. Here, we enrolled patients who underwent hepatectomy due from 2010 2014. Analyses were performed test potential ALBI monitor long-term survival subjects varying A total 265 participants recruited....
Abstract A precise and noninvasive method to predict posthepatectomy liver failure (PHLF) in clinical practice is still lacking. Liver fibrosis or cirrhosis accompanied with varying degrees of portal hypertension plays an important role the occurrence PHLF hepatocellular carcinoma (HCC) patients. This study aims compare predictive ability albumin-bilirubin score spleen thickness ratio (ALBI/ST) versus fibrosis-4 index (FIB-4) aspartate aminotransferase platelet count (ARPI) for PHLF. We...
Synaptojanin 2 Binding Protein (SYNJ2BP) is essential to cell proliferation. Previous studies show that SYNJ2BP participates in sprouting angiogenesis, which plays an important part several abnormal conditions including cancer. However, the activity of hepatocellular carcinoma (HCC) has not been elucidated yet. Firstly, real-time PCR and western blotting (WB) were adopted evaluate expressions HCC tissues lines. Secondly, we did follow-up prognostic study explore association expression...
Cholangiocarcinoma (CCA), which is highly malignant, shows a relatively poor prognosis, due to the insensitivity of tumour chemotherapy and radiotherapy. Photodynamic therapy (PDT) has become promising palliative therapeutic option for patients with unresectable cholangiocarcinoma while functional amount ROS limited by intracellular redox systemen. Sulfasalazine (SASP), well-known anti-inflammatory agent, also acts as an inhibitor amino acid transport system xc (xCT), decreases glutathione...
Aim: To analyze the learning curve (LC) for robotic natural orifice specimen extraction surgery (NOSES) colorectal neoplasms and evaluate safety feasibility during initial LC. Method: Patients who consecutively underwent NOSES performed by two surgeons between March 2016 October 2019 were analyzed retrospectively. The operation time was evaluated using cumulative sum method to clinicopathological data before after completion of LC extracted compared feasibility. Results: In total, 99 66...
The present study aims to evaluate the effect of ethyl acetate extract Cichorium (EAEC) as a novel photosensitizer in photodynamic therapy (PDT) colorectal carcinoma (CRC) HCT116 and SW620 cells. absorption fluorescence spectra EAEC were measured using UV-vis spectrophotometer spectrophotometer, respectively. EAEC-induced reactive oxygen species (ROS) production cells was detected 2',7'-dichlorodihydrofluorescein diacetate (DCFH-DA) glutathione/glutathione disulfide (GSH/GSSG). photo- dark...
Objective: To explore the safety and feasibility of da Vinci robot surgical systems in natural orifice specimen extraction surgery (NOSES) for rectal neoplasms. Methods: A descriptive cohort study was used. Inclusion criteria: (1) age ≥18 years old; (2) diagnosis cancer by biopsy via colonoscopy or benign neoplasm locating rectum that could not be resected locally through anus; (3) R0 resection can achieved preoperative evaluation; (4) CDmax (maximum circumferential diameter) ≤5 cm specimens...
Post-pancreaticoduodenectomy hemorrhage is a life-threatening complication that occurs in 2-10% of patients. The most common location for post-pancreaticoduodenectomy the gastroduodenal artery stump. Nonetheless, unusual sources hemorrhage, which are hard to locate, exist. Here, we report rare postoperative after robotic-assisted pancreatoduodenectomy pancreatic head cancer. A 67-year-old man presenting with appetite loss, general fatigue and painless jaundice was admitted our ward. patient...
Endoscopic retrograde cholangiopancreatography (ERCP) and biliary stent placement are standard palliative care procedures for patients with unresectable cholangiocarcinoma. However, the bile duct mucosa cannot be observed directly during of a light diffuser in photodynamic therapy (PDT) biopsy. SpyGlass can solve above two problems. In this paper, we report case patient who presented obstructive jaundice underwent endobiliary stenting several times. cholangiocarcinoma hyperplasia still led...
Abstract Background : To analyze the initial learning curve (LC) for robot-assisted pancreaticoduodenectomy (RAPD) and compare RAPD during LC with open (OPD) in terms of outcome. Methods This study is a retrospective review patients who consecutively underwent between October 2015 May 2019 our hospital. Experiences from 30 consecutive cases, considered single surgeon team, were compared those laparotomy cases same period Preoperative demographic comorbidity data obtained. Perioperative on...