A5035953410- Reproductive Biology and Fertility
- Advanced Drug Delivery Systems
- Sperm and Testicular Function
- Poisoning and overdose treatments
- Rabies epidemiology and control
- Pharmacological Effects of Natural Compounds
- Sulfur Compounds in Biology
- Congenital Anomalies and Fetal Surgery
- Advanced Nanomaterials in Catalysis
- Pesticide and Herbicide Environmental Studies
- Oral Health Pathology and Treatment
- Bone health and treatments
- Curcumin's Biomedical Applications
- Proteins in Food Systems
- Moringa oleifera research and applications
- Oral health in cancer treatment
- Paraquat toxicity studies and treatments
- Migraine and Headache Studies
- Bone health and osteoporosis research
- Marine Invertebrate Physiology and Ecology
- Parasitic Infections and Diagnostics
- Pesticide Exposure and Toxicity
- Pain Mechanisms and Treatments
- Neurological Disorders and Treatments
- Acne and Rosacea Treatments and Effects
Cairo University
2016-2024
Acne vulgaris, a prevalent skin condition, arises from an imbalance in flora, fostering bacterial overgrowth. Addressing this issue, clindamycin molecularly imprinted polymeric nanoparticles (Clin-MIP) loaded onto polyurethane nanofiber scaffolds were developed for acne treatment. Clin-MIP was synthesized via precipitation polymerization using methacrylic acid (MAA), ethylene glycol dimethacrylate (EGDMA), and azoisobutyronitrile (AIBN) as functional monomers, crosslinkers, free-radical...
Moringa oleifera extract (Lam) has many antioxidant and protective properties. Objective: to investigate the activities of Lam in counteracting high oxidative stress caused by acute sub-lethal aluminium phosphide (AlP) intoxication rat heart. These will be detected histopathological examination some biomarkers. a single dose Alp (2 mg/kg body weight) was administered orally, given orally at (100 one hour after receiving AlP rats. significant cardiac changes with increase malondialdehyde...
Abstract: To prolong the residence time of dosage forms within gastrointestinal tract until all drug is released at desired rate one real challenges for oral controlled-release delivery systems. This study was designed to develop a floating matrix tablet and raft system Mebeverine HCl (MbH) evaluate different excipients their behavior in vitro profiles. Oral pharmacokinetics optimum tablet, formula, marketed Duspatalin ® 200 mg retard as reference were studied beagle dogs. The optimized...
Objective: To develop and evaluate zolmitriptan spanlastics (Zol SLs) as a brain-targeted antimigraine delivery system. Spanlastics (SLs) prepared using span 60: tween 80 (70:30%, respectively) gave the highest percentage of entrapment efficiency (EE%). Materials methods: A total 60 adult male Wistar albino rats were divided into six groups (n=10 rats/group). Group 1 (Control) comprised serving negative control. 2 was treated with glyceryl trinitrate (NTG) served positive Groups 3 (NTG+Zol...
The aim of this study was to evaluate the effect atorvastatin on bone formation and resorption markers in ovariectomized rats (experimental study), its mineral density (BMD) postmenopausal osteoporotic women (clinical study).The involved experimental clinical aspects. In aspect, 42 female Wistar were divided into five groups: Group I (n=6; sham-operated), II 1 mL carboxymethyl cellulose [CMC] administered orally), III 20 mg/kg orally administered), IV (n=12; untreated [OVX] served as a model...
Abstract Iatrogenic botulism resulting from the substantial increase in use of botulinum neurotoxin type A (Bo NT ‐A) treatment is rarely reported. We aimed to describe a large iatrogenic outbreak Egypt June–July 2017. Nine patients developed after receiving intramuscular injections Bo ‐A (dose: 200–300 IU) treat cerebral palsy (N = 7), spastic dystonia 1) and hyperhidrosis 1). Detailed findings were available five nine cases. Patients admitted hospital 5‐10 days injection. Complaints...
Introduction: Snakebite is an Egyptian health problem since ancient Egypt. Meanwhile, there still no controlled geographical and medical studies on locally prevalent snake family intoxication. Aim Methods: The present study aimed to investigate local snakebites presentations, management, prognosis, the effect of polyvalent antivenom, produced by Holding Company for Biological Products Vaccines (VACSERA) through year 2015. Results: A total 87 caused venomous nonvenomous species were recorded....
Introduction Aluminum phosphide (ALP) is a cheap, widely available worldwide, especially in developing countries, highly toxic pesticide, with lot of reported cases suicidal many countries including Egypt. ALP readily as fumigant for stored cereal grains highl
Redox equilibrium is altered due to elevation of reactive oxygen species (ROS) or inadequate antioxidant defense, therapeutic effects natural such as curcumin (CMN) have been investigated. The aim this study was investigate the beneficial (a polyphenol) on oxidative status lung and liver assessment level interleukin-6 (IL-6) in rats against paraquat toxicity. Forty adult male wistar were divided into five groups with eight animals each followed: Group 1: control, 2: received olive oil. 3:...
Abstract In vitro maturation (IVM) of oocytes is an important application in assisted reproductive medicine and biology research. It can provide high quality from unstimulated ovaries. However, IVM remains a challenge mammalian species, has only been achieved with limited degrees success. This study was carried out to investigate the effect adding recombinant Follicle Stimulating Hormone (rFSH), Luteinizing (rLH) or combination both hormones on rabbit oocytes, as considered model system for...