A5088006979- Reproductive tract infections research
- Microwave Engineering and Waveguides
- Antenna Design and Analysis
- Advanced Antenna and Metasurface Technologies
- Mosquito-borne diseases and control
- Reproductive System and Pregnancy
- RFID technology advancements
- Cervical Cancer and HPV Research
- Energy Harvesting in Wireless Networks
- Crystallization and Solubility Studies
- Reproductive Physiology in Livestock
- Synthesis and Biological Evaluation
- Chemical Thermodynamics and Molecular Structure
- Lubricants and Their Additives
- Tribology and Wear Analysis
- Viral Infections and Vectors
- SARS-CoV-2 and COVID-19 Research
- Synthesis and biological activity
- COVID-19 Clinical Research Studies
- Malaria Research and Control
- Liver Disease Diagnosis and Treatment
- Cloud Data Security Solutions
- Millimeter-Wave Propagation and Modeling
- Advanced MIMO Systems Optimization
- HIV Research and Treatment
Translational Health Science and Technology Institute
2013-2024
Terna Dental College and Hospital
2024
Creative Commons
2024
All India Institute of Medical Sciences Raipur
2024
All India Institute of Medical Sciences
2024
Vellore Institute of Technology University
2024
King George's Medical University
2022-2023
Manipal Academy of Higher Education
2023
Institute of Liver and Biliary Sciences
2019-2021
Jaypee Institute of Information Technology
2015-2018
BackgroundAccurate quantitation of immune markers is crucial for ensuring reliable assessment vaccine efficacy against infectious diseases. This study was designed to confirm standardised performance SARS-CoV-2 assays used evaluate COVID-19 candidates at the initial seven laboratories (in North America, Europe, and Asia) Coalition Epidemic Preparedness Innovations (CEPI) Centralized Laboratory Network (CLN).MethodsThree ELISAs (pre-spike protein, receptor binding domain, nucleocapsid), a...
This document investigates empirically the role of social media in consumer decisionmaking process. A quantitative survey how deep an effect experience bears with reference to media. Consumers' views on products and services are more influenced by third parties digital sphere then transferred perceptions real world. Consumers empowered such a way as it makes impossible for marketers manage content, timing, or frequency conversations among users. The results show that use impacts satisfaction...
Japanese encephalitis virus (JEV) is a neurotropic flavivirus, which causes viral leading to death in about 20–30% of severely-infected people. Although JEV known be its replication non-neuronal cells peripheral tissues likely play key role dissemination and pathogenesis. We have investigated the effect infection on cellular junctions number cells. show that affects permeability barrier functions polarized epithelial at later stages infection. The levels some tight adherens junction proteins...
Background Japanese encephalitis virus (JEV) is a major cause of viral in South and South-East Asia. Lack antivirals non-availability affordable vaccines these endemic areas are setback combating JEV other closely related viruses such as West Nile dengue virus. Protein secondary structure mimetics excellent candidates for inhibiting the protein-protein interactions therefore serve an attractive tool drug development. We synthesized derivatives containing backbone naturally occurring lupin...
Abstract We screened a siRNA library targeting human tyrosine kinases in Huh-7 cells and identified c-terminal Src kinase (Csk) as one of the involved dengue virus replication. Knock-down Csk expression by siRNAs or inhibition an inhibitor reduced RNA levels but did not affect viral entry. partially colocalized with replication compartments. Dengue infection was drastically lacking three ubiquitous src family kinases, Src, Fyn Yes. knock-down these failed to block suggesting that effect is...
Citation Agrawal T, Bhengraj AR, Vats V, Salhan S, Mittal A. Expression of Toll-like receptors (TLR) 2, TLR 4 and inducible nitric oxide synthase (iNOS) in cervical monocytes Chlamydia trachomatis-infected women their role host immune response. Am J Reprod Immunol 2011; 66: 534–543 Problem To study the innate response -TLR2 iNOS expression female genital trachomatis infection. Method 4, was evaluated by real-time PCR C. asymptomatic, mucopurulent cervicitis (MPC), fertility disorders (FD)...
Around 10,000 people die each year due to severe dengue disease, and two-thirds of the world population lives in a region where disease is endemic. There has been remarkable progress virus vaccine development; however, there are no licensed antivirals for none appear be clinical trials. We took approach repositioning approved drugs anti-dengue activity by screening library pharmacologically active compounds. identified N-desmethylclozapine, fluoxetine hydrochloride, salmeterol xinafoate as...
Most of the studies on 60-kDa and 10-kDa chlamydial heat shock proteins (HSPs) to date have been carried out with blood lymphocytes or serum antibody responses, which do not provide a clear picture actual pathogenesis as they differentiate primary infection from recurrent infection. Thus, in present study induction immune response was evaluated by studying lymphoproliferation both cervical peripheral synthetic peptides cHSP60, cHSP10 major outer membrane protein (MOMP) antigen. In addition,...
Intracellular protein trafficking pathways are hijacked by viruses at various stages of viral life-cycle. Heterotetrameric adaptor complexes (APs) mediate vesicular distinct intracellular sites and essential for maintaining the organellar homeostasis. In present study, we studied effect AP-1 AP-3 deficiency on flavivirus infection in cells functionally lacking these proteins. We show that participate life-cycle stages. AP-3-deficient showed delay initiation Japanese encephalitis virus dengue...
Following Japanese encephalitis virus (JEV) infection neutralizing antibodies are shown to provide protection in a significant proportion of cases, but not all, suggesting additional components immune system might also contribute elicit protective response. Here we have characterized the role T cells offering adult mice infected with JEV. Mice lacking α/β–T (TCRβ–null) highly susceptible and die over 10–18 day period as compared wild-type (WT) which resistant. This is associated high viral...
This paper presents a multiple input output (MIMO) antenna for multiband operation based on meander lines with L shaped metallic strip. Meander is basically monopole loaded sections of short circuited transmission line that acts as inductor and alter the impedance characteristics antenna. Antenna size miniaturization 69 % has been achieved by placing double U slots ground plane slot DGS (Defective Ground Structure) used to reduce mutual coupling between elements. The values envelope...
Phase diagram of benzoic acid (BA)–o-chloro (o-CBA) system has been studied by thaw melt method and the results show formation a simple eutectic mixture. Heats fusion values components mixture were determined with help differential scanning calorimeter. Excess Gibb's free energy (GE), excess enthalpy (HE), entropy (SE) mixing pre-, post-, calculated. FT-IR spectroscopic studies ab initio calculations done to have an idea about nature interaction between molecules in Linear velocities...
Abstract Background Chlamydia trachomatis infection of the female genital tract can lead to serious sequelae resulting in fertility related disorders. Little is known about mechanism leading induced pathology and factors responsible for it. As only some women develops reproductive disorders while majority clears without any severe sequalae, mucosal immune response with or was studied identify which may final clinical outcome chlamydial infection. Methods Myeloid DCs (mDCs) plasmacytoid...
The regulation of immune response and chlamydial infectious load in the cervix human females is largely unknown. Infectious terms inclusion-forming units (IFUs) was determined by quantitative cultures Chlamydia-positive women, asymptomatic women with mucopurulent cervicitis (MPC) fertility disorders (FD). CD4+, CD8+, CD14+ cells, myeloid plasmacytoid dendritic cells (mDCs pDCs) were quantified flow cytometry. Cervical cytokines, levels β-estradiol C-reactive protein (CRP) serum cervical...
The present paper proposes a novel miniaturized and selective half-mode substrate integrated waveguide (HMSIW) bandpass filter (BPF) using Hilbert fractal geometry. A non-uniform horizontal periodical DGS (HPDGS) is introduced in the ground plane to miniaturize it further obtain wide steep outband rejection enhance filter's performance. three-pole with center frequency of 3.5 GHz simulated, analyzed designed on low-cost FR-4 (εr = 4.4). becomes small, shows low insertion loss 1.1 dB return...
Little is known about concurrent expression of cervical cytokines and their regulation by sex hormones during primary or recurrent chlamydial infections in humans. Cytokine (interleukin-1β [IL-1β], IL-6, IL-10, interferon-γ [IFN-γ], tumor necrosis factor-α [TNF-α]) concentrations washes serum samples, along with levels β-estradiol progesterone women healthy controls, were measured ELISA. Women had significantly higher IFN-γ than did infections. Significant negative correlation was found...
The phase diagram of the benzamide + o-chlorobenzoic acid system has been studied by thaw−melt method, and results show formation a simple eutectic mixture. Values enthalpies fusion pure components mixture were determined from DSC studies. Excess Gibb's energy (GE), excess enthalpy (HE), entropy (SE) mixing pre-, post-, also calculated using activity coefficient data. Linear velocities solidification at different undercooling rates. values thermodynamic functions, linear velocity...