A5101594760- Wnt/β-catenin signaling in development and cancer
- Cancer-related gene regulation
- RNA Research and Splicing
- Soil Carbon and Nitrogen Dynamics
- Epigenetics and DNA Methylation
- Gut microbiota and health
- Autophagy in Disease and Therapy
- Metamaterials and Metasurfaces Applications
- Topological Materials and Phenomena
- Tea Polyphenols and Effects
- Polysaccharides and Plant Cell Walls
- Endoplasmic Reticulum Stress and Disease
- Genetic factors in colorectal cancer
- Digital Holography and Microscopy
- Nutrition, Genetics, and Disease
- Microwave Engineering and Waveguides
- Chaos-based Image/Signal Encryption
- RNA modifications and cancer
- Bacillus and Francisella bacterial research
- Seed and Plant Biochemistry
- Ubiquitin and proteasome pathways
- Plant nutrient uptake and metabolism
- Advanced Optical Imaging Technologies
- TGF-β signaling in diseases
- Multiferroics and related materials
Anhui University
2014-2024
Hebei University of Engineering
2022
Nanjing Normal University
2022
Homeobox (HOX) genes encode a family of transcription factors, which play crucial roles in numerous processes, and their dysregulation is involved the carcinogenesis many human cancers. In present study, we investigated HOXC8 non-small cell lung cancer (NSCLC). We showed that was upregulated clinical NSCLC specimens compared to normal tissues, high expression correlated with tumor node metastasis (TNM) stage, status, lymph nodal status poor relapse-free survival for patients. Functionally,...
Tartary buckwheat is a popular natural grain commonly used as functional food in various countries. This study aimed to prepare dietary fiber with improved biological activity using liquid fermentation of Aspergillus niger and elucidate its physicochemical properties related mechanisms. Compared unfermented fiber, increased the soluble content, thereby improving fiber's physical chemical such water, oil retention capacity, swelling cholesterol-binding capacity. Fermented treatment for 14...
Curcumin, a spice component as well traditional Asian medicine, has been reported to inhibit proliferation of variety cancer cells but is limited in application due its low potency and bioavailability. Here, we have assessed the therapeutic effects novel water soluble curcumin analog, 3,5-bis(2-hydroxybenzylidene)tetrahydro-4H-pyran-4-one glutathione conjugate [EF25-(GSH)2], on hepatoma cells. Using MTT colony formation assays, determined that EF25-(GSH)2 drastically inhibits cell line HepG2...
Abstract Triple‐negative breast cancer (TNBC) is the most aggressive subtype which accounts for 15%‐20% of all cases. The management TNBC has remained a challenge due to its lack targeted therapy. Previously, we reported that homeobox C8 (HOXC8) was involved in metastasis and migration cells. By chromatin immunoprecipitation luciferase assays, found HOXC8 functioned as transcription factor activate matrix Gla protein (MGP) gene, leading an increase proliferation, anchorage‐independent...
// Yong Li 1 , Fengmei Chao Bei Huang Dahai Liu Jaejik Kim 2 Shuang 3,4 Center for Stem Cell and Translational Medicine, School of Life Sciences, Anhui University, Hefei, Anhui, China Department Biostatistics, Georgia Regents Augusta, GA, USA 3 Biochemistry Molecular Biology, Medical College Georgia, 4 E-institute Shanghai Municipal Education Committee, University Traditional Chinese Shanghai, Correspondence: Li, email: Huang, Keywords : HOXC8, CDH11, breast cancer, transcription, metastasis...
// Yang Zhang 1, * , Chenchen Mingsheng 2, Houli Liu 1 Chen Gong Jie Shanshan Xu Jin Zou Yuanzhong Kai and Yong Li School of Life Sciences, Anhui University, Hefei, Province, China 2 Department Oncology, Tongji Hospital, Medical College, Huazhong University Science Technology, Wuhan, Hubei, These authors contributed equally to this work Correspondence to: Li, email: liyongahu@163.com Keywords: CDH11; ILF3; HOXC8; transcriptional regulation; breast cancer Received: June 27, 2017 Accepted:...
Abstract Non-mechanical ptychographic encoding (NPE) transforms the secret information into series of diffractive patterns through a spatial light modulator (SLM), saving need to fabricate objects. Conventionally, shares in extended visual cryptography (EVC) are printed on transparent sheets or fabricated with optical elements and metasurface, but these methods expensive disposable. To solve problems, we proposed an image encryption scheme that combines EVC NPE. In process, is decomposed...
// Fengmei Chao 1 , Jun Zhang 2,3 Yang Houli Liu Chenchen Juan Wang 2 Yanjun Guo Xiaohong Wen Kaiye Bei Huang Daihai and Yong Li Anhui University, School of Life Sciences, Center for Stem Cell Translational Medicine, Hefei, Province, P. R. China 3 The Key Laboratory Developmental Genes Human Disease, Ministry Education, Institute Science, Southeast Nanjing, Correspondence to: Li, email: Keywords : EMB, transcription, HOXC8, breast cancer, tumorigenesis Received February 05, 2015 Accepted May...
Abstract Fungi typically prevail in acidic soils and have a stronger preference for complex organic compounds than bacteria. Thus, we hypothesized that fungi would play more important role gross nitrogen (N) transformation soil bacteria, the dominance of on N transformations increase following inputs. Herein, determined bacterial fungal contributions to processes using 15 tracing approach combined with selective inhibition an upland under aerobic conditions. Streptomycin was used as...
Abstract RNA-guided genome editing based on the CRISPR-Cas system is currently most effective technique. Here, we report that SviCas3 from subtype I-B-Svi Cas in Streptomyces virginiae IBL14 an and DNA-guided DNA endonuclease suitable for gene and/or base of prokaryotic eukaryotic cell genomes. The efficiency guided by was no less than RNA. It should be noted off-target effects or indel-formation were detected targeted sequencing. In particular, t-DNA, as a template guide, does not require...