A5101741526- Oral and Maxillofacial Pathology
- Head and Neck Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Cancer Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Head and Neck Surgical Oncology
- Cardiac Imaging and Diagnostics
- Bone Tumor Diagnosis and Treatments
- Tumors and Oncological Cases
- Ear and Head Tumors
- Salivary Gland Disorders and Functions
- Reconstructive Surgery and Microvascular Techniques
- Oral Health Pathology and Treatment
- Spacecraft Dynamics and Control
- Sarcoma Diagnosis and Treatment
- Nuclear physics research studies
- Oral and gingival health research
- Astro and Planetary Science
- Atomic and Molecular Physics
- Radiopharmaceutical Chemistry and Applications
- Medical Imaging and Pathology Studies
- Radiomics and Machine Learning in Medical Imaging
- Vascular Malformations and Hemangiomas
- Cardiac electrophysiology and arrhythmias
Chugai Pharma (United States)
2025
Tohoku Medical and Pharmaceutical University Hospital
2024
Juntendo University
2010-2024
Chitose Institute of Science and Technology
2024
Tokyo National Hospital
2023
Tohoku Medical and Pharmaceutical University
2023
Kitasato University
2008-2020
Shizuoka University
2003-2013
Kyushu University
1988-2013
Fukuda Denshi (Japan)
1976-2012
Abstract Purpose. To demonstrate appropriate treatment methods for mandibular osteoradionecrosis (ORN) by evaluating previous results. Methods. The relationship between the time interval after radiation therapy (RT) and severity of ORN was examined. Eighty‐seven patients were classified according to extent lesion (grades), cure rates calculated RT modality, grade, method ORN. Results. later developed higher dose irradiation, particularly among who received external RT, more it progressed....
The purpose of our study was to evaluate the diagnostic performance sonographic elastography and B-mode sonography individually combined in differentiation reactively metastatically enlarged cervical lymph nodes.Eighty-five nodes (metastatic, n = 53; reactive, 32) from 37 patients were examined by both this prospective study. Elastographic patterns determined on distribution percentage node area with high elasticity (hard), pattern 1 being an absent or very small hard 5, a occupying entire...
Regional cerebral blood flow was measured in six healthy volunteers by positron emission tomography during identification of speaker and emotion from spoken words. The task activated several audio-visual multimodal areas, particularly the temporal poles both hemispheres, which may be involved connecting vocal attributes with visual representations speakers. regions cerebellum frontal lobe, suggesting a functional relationship between those emotion. results suggest that different anatomical...
Abstract Histologic analysis of squamous cell carcinoma the lower alveolus shows 2 basic patterns tumor spread in relation to mandible: an infiltrative one and expansive one. While invades mandible by destroying bone or through cortical defects some spaces form, does this only eroding which degree resorption seems be proportional advancement. A comparison between radiologic histologic features discloses that radiologically detected are not necessarily correlated with involvement. However,...
There are no data concerning the incidence of provoked coronary arterial spasms via intracoronary administration ergonovine (ER). This study sought to establish due injection ER in Japanese patients who underwent angiography. The subjects were 596 consecutive (369 men, mean age 64.2 ±10.3 years) studied with a selective test. was administered total doses 40 µg into right artery and 64 left artery. A positive spasm defined as or subtotal occlusion. Coronary vasospasms determined 173 (29.0%)....
4510 Background: The phase III trial (JCOG9204) comparing postoperative adjuvant chemotherapy using cisplatin plus 5- fluorouracil (5-FU) with surgery alone showed superior disease-free survival in for patients (pts) esophageal squamous cell carcinoma (ESCC) (Ando N, et al, J Clin Oncol 2003). This was conducted to determine the optimal timing giving chemotherapy. Methods: Pts c-stage II, (excluding T4) ESCC were randomized. In arm A, two courses of (80 mg/m2, div day1) 5-FU (800 ci day1–5)...
Recently Tomonaga and Schwinger have independently developed a covariant formulation of quantumelectrodynamics (super-many-time theory), successfully applied it to the explanation Lamb shift in hydrogen atom anomalous magnetic moment electron. They shown that, although present theory fields, general, gives infinte answers such field reaction problems, since cannot be formulated Lorentz- gauge-covariant way without introduction singular delta function Jordan Pauli, is nevertheless possible...
Abstract Alectinib, which is marketed under the name Alecensa, an orally administered and highly potent anaplastic lymphoma kinase (ALK) inhibitor used for treatment of ALK-positive non-small-cell lung cancer. The distinctive structural feature alectinib its indole-fused tetracyclic scaffold, efficient synthesis method crucial in establishing manufacturing process. While methodology developed first-in-human study has proved to be practical preparation indole-core on a multi-kilogram scale,...
FRONTAL cortical damage can lead to changes in affective aspects of personality. However, the difficulty dissociating such abnormalities from cognitive disorders has overshadowed most previous findings. Regional cerebral blood flow (rCBF) was measured with positron emission tomography (PET) while normal subjects were assessing facial attractiveness. Two left frontal regions showed a significant increase rCBF The increased anterior cortex correlated overall percentage assessments face as...
Hepatocyte growth factor (HGF) is thought to play a role in cell motility and invasion. Matrix metalloproteinases (MMPs) have been implicated invasion metastasis of tumor cells. We previously reported that the Ets-oncogene family transcription E1AF positively regulates MMP genes transient expression assays overexpression gene confers an invasive phenotype on breast cancer Here we examined effect HGF terms potential oral squamous carcinoma line HSC3. stimulated gene. The levels MMP-1, -3 -9...
A randomized controlled trial has been started in Japan to compare the utility of palliative chemotherapy containing paclitaxel and carboplatin (TC) with cisplatin (TP) as a standard treatment for patients newly diagnosed Stage IVB, persistent or recurrent cervical cancer who are not amenable curative local therapy. This was designed evaluate non-inferiority TC measured by number hospitalized days an indicator quality life (QOL) when compared TP combination The primary endpoint is overall...
Background and objectives There have been few studies comparing the clinical usefulness for induction of coronary artery spasm (CAS) between acetylcholine (ACh) ergonovine (ER). This study is designed: (1) to examine duration effect after intracoronary injection ACh on responsible vessels using a 0.014 inch, 15 MHz Doppler guide wire, (2) evaluate efficacy two pharmacological agents, ER, CAS in patients with <50% stenosis cardiac laboratory. Methods Phasic flow velocity patterns were...
For the high-lying doubly excited states of H- and He, authors have quantitatively examined diabaticity at close avoided crossings between two hyperspherical adiabatic potentials confirmed that in diagrams potential curves can be reconnected 'diabatically' for N manifolds investigated here. Using these diabatically connected potentials, they calculated energy levels states, i.e. 1Se from N=7-9 hydrogenic thresholds H-, as well those with N=6 7, 1P0 1De N<or=4 He. Their results agree...
The doubly excited 1Se states of H- and He are studied by using the hyperspherical coordinate representation adiabatic approximation. potentials below N<or=6 hydrogenic thresholds calculated means trial functions which constructed from harmonics analytical channel proposed Lin (1981, 1982). lowest few belonging to Nth threshold have close avoided crossings with higher ones (N-1)th threshold. It is shown that can be connected diabatically at these crossing points. According this prescription,...