A5005035572- Hormonal Regulation and Hypertension
- Adrenal and Paraganglionic Tumors
- Lipoproteins and Cardiovascular Health
- Adrenal Hormones and Disorders
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- COVID-19 Clinical Research Studies
- Renal and Vascular Pathologies
- Diabetes and associated disorders
- Blood Pressure and Hypertension Studies
- Vitamin C and Antioxidants Research
- Diet and metabolism studies
- Ion Transport and Channel Regulation
- Pancreatic function and diabetes
- Cancer, Lipids, and Metabolism
- Lipid metabolism and disorders
- Cancer, Stress, Anesthesia, and Immune Response
- Diabetes Treatment and Management
- Pharmaceutical Economics and Policy
- Antiplatelet Therapy and Cardiovascular Diseases
- Pharmacological Effects of Natural Compounds
- Streptococcal Infections and Treatments
- Cardiovascular Health and Disease Prevention
- Angiogenesis and VEGF in Cancer
- Congenital Heart Disease Studies
- Vascular anomalies and interventions
University of Padua
2014-2024
University of Verona
2017-2018
Azienda Ospedaliera Universitaria Integrata Verona
2016
The discovery of angiotensin converting enzyme-2 (ACE-2) as the receptor for SARS- CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) has implicated renin-angiotensin-aldosterone system in acute respiratory distress syndrome (ARDS) and failure patients with coronavirus disease-19 (COVID-19). enzyme-1-angiotensin II-angiotensin AT1 pathway contributes to pathophysiology ARDS, whereas activation ACE-2-angiotensin(1-7)-angiotensin AT2 ACE-2-angiotensin(1-7)-Mas pathways have been shown be...
Even though SARS-CoV-2 was declared by WHO as constituting no longer a public health emergency, the development of effective treatments against infection remains critical issue to prevent complications, particularly in fragile patients. The protease inhibitor nafamostat, currently used Japan and Korea for pancreatitis, owing its anticoagulant properties disseminated intravascular coagulation (DIC), is appealing treatment COVID-19 infection, because it potently inhibits transmembrane serine 2...
As metoclopramide stimulates aldosterone secretion, we tested its usefulness in the assessment of lateralization primary aldosteronism by adrenal vein sampling (AVS).Prospective within-patient study consecutive patients undergoing AVS for subtyping.We compared diagnostic accuracy baseline and postmetoclopramide index relative (to cortisol) secretion indices (RASI) each gland with aldosterone-producing adenoma (APA) determined four corners criteria as reference diagnosis.We recruited 93 (mean...
Purpose Familial hyperaldosteronism type 1 (FH-1) is an autosomal dominant form of primary aldosteronism (PA), featuring a marked phenotypic heterogeneity, ranging from mild forms PA and arterial hypertension (HT) to severe complicated by stroke at young age. Affected patients usually reach the fertile age; hence, transmission disease offspring common. Notwithstanding this, only anecdotal reports FH-1 in pregnancy exist recommendations for treatment remain vague.Materials Methods Results We...
Summary Vertebral osteomyelitis (or spondylodiscitis) is steadily increasing in Western countries and often results from hematogenous seeding, direct inoculation during spinal surgery, or contiguous spread an infection the adjacent soft tissue. We present case of a 67-year-old white patient with type 2 diabetes who went to Hospital for high fever, back pain, worsening known infected ulcers left foot. Despite intravenous antibiotic treatment surgical debridement foot infection, fever lower...
A 49 years old woman (weight 68 kg, BMI 27.3 kg/m 2 ) with heterozygous familial hypercholesterolemia (HeFH) and multiple statin intolerance muscle aches creatine kinase elevation, presented at the Outpatient Lipid Clinic of Verona University Hospital in May 2015. Hypercholesterolemia was firstly diagnosed during adolescence, followed adulthood by a diagnosis Cogan's syndrome, rheumatologic disorder characterized corneal inner ear inflammation. No xanthomas, arcus, or vascular bruits were...
Primary adrenal insufficiency (AI) due to bilateral adrenalectomy is not uncommon and causes skin hyperpigmentation, which worsens quality of life. Case description: A 50-year-old lady presented with hyperpigmentation after spare for recurrent primary aldosteronism. In 2002 she has her first unilateral was cured at follow-up. After 16 years developed aldosteronism, treated by adrenalectomy. She thereafter AI started glucocorticoid replacing therapy, did prevent the development full-blown...
Background: blockade of the RAAS lowered incidence Diabetes Mellitus in randomized clinical trials, but whether de-activation can elicit same beneficial effect patients with renovascular hypertension (RVH) is unknown. Aim: to verify if endovascular treatment (EVT) could improve glycemic control atherosclerotic RVH. Methods: METRAS study (http://clinicaltrials.gov/show/NCT01208714, a trial comparing EVT on top optimal medical therapy versus alone (OMT) GFR ischemic and contralateral kidney...
An increase in the appearance of diabetes mellitus at young age is observed, and not necessarily type 1 involced. We report case a 35-year-old patient, with family history diabetes, 2 onset (Diabetology).