A5070161364- Hormonal Regulation and Hypertension
- Liver Disease and Transplantation
- Adrenal and Paraganglionic Tumors
- Adrenal Hormones and Disorders
- Liver Disease Diagnosis and Treatment
- Biblical Studies and Interpretation
- Abdominal vascular conditions and treatments
- Vascular anomalies and interventions
- Renal and Vascular Pathologies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Bariatric Surgery and Outcomes
- Cardiac Structural Anomalies and Repair
- Aortic aneurysm repair treatments
- Medical Imaging and Pathology Studies
- Esophageal and GI Pathology
- Cardiac, Anesthesia and Surgical Outcomes
- Organ Transplantation Techniques and Outcomes
- Pleural and Pulmonary Diseases
- Aortic Disease and Treatment Approaches
- Coronary Artery Anomalies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Vascular Procedures and Complications
- Metastasis and carcinoma case studies
- Sarcoidosis and Beryllium Toxicity Research
- Development, Ethics, and Society
University of Padua
2016-2025
Azienda Ospedaliera di Padova
2003-2023
Research Institute of Radiology
2016-2021
National Taiwan University Hospital
2019
University Radiology
2016
Ospedale San Bassiano
2008-2012
Genomics (United Kingdom)
2001
We sought to measure the clinical benefits of adrenal venous sampling (AVS), a test recommended by guidelines for primary aldosteronism (PA) patients seeking surgical cure, in large registry PA submitted AVS. Data 1625 consecutive AVS 19 tertiary referral centers located Asia, Australia, Europe, and North America were collected multicenter international registry. The end points rate bilateral success, ascertained lateralization PA, adrenalectomy, cured arterial hypertension among AVS-guided...
Adrenal venous sampling (AVS) is the key test for subtyping primary aldosteronism (PA), but its interpretation varies widely across referral centers and this can adversely affect management of PA patients.To investigate in a real-life study rate bilateral success identification unilateral their impact on blood pressure outcomes subtyped by AVS.In retrospective analysis largest international registry individual AVS data (AVIS-2 study), we investigated how different cut-off values selectivity...
Abstract Background Portal vein thrombosis (PVT) is the most common thrombotic complication in cirrhosis; however, local risk factors involved its pathogenesis are still not fully investigated. The aim of study was to evaluate hemostasis and endothelial damage portal patients with cirrhosis hypertension. Methods Adult cirrhotics undergoing transjugular intrahepatic portosystemic shunt were consecutively enrolled. Rotational thromboelastometry (ROTEM), dosage total circulating...
Background & Aims: In clinical practice, the reduction of porto-caval pressure gradient (PCPG) following trans-jugular intra-hepatic porto-systemic shunt (TIPS) does not always meet recommendation current guidance. We evaluated impact different degrees PCPG reduction, measured at end an elective TIPS, on ascites control, recurrence portal hypertension-related bleeding (PHRB) and survival. Approach Results: Cirrhotic patients receiving TIPS for refractory (RA) or secondary prophylaxis...
Pancreatico-duodenal artery (PDA) pseudoaneurysms are rare vascular conditions with high mortality rates after rupture and they frequently secondary to pancreatitis, surgery, trauma or infection.Due the risk of bleeding, it is mandatory treat all pseudoaneurysms, regardless their size symptomatology.First option treatment open surgical repair, but has rate, especially in hemodynamically unstable patients.In recent years, percutaneous ultrasonography (US)-or computed tomography-guided...
Abstract Context Adrenal gland imaging is recommended by the current guidelines for workup of primary aldosteronism (PA). However, its diagnostic performance has not been established in large, multiethnic cohorts patients who undergo adrenal vein sampling (AVS) and adrenalectomy. Objective This work aims to assess accuracy cross-sectional imaging. Methods international multicenter study took place tertiary referral centers. A total 1625 PA seeking surgical cure were enrolled an involving 19...
Background: The pulsatile secretion of adrenocortical hormones and a stress reaction occurring when starting adrenal vein sampling (AVS) can affect the selectivity also assessment lateralization sequential blood is used. We therefore tested hypothesis that simulated could decrease diagnostic accuracy index for identification aldosterone-producing adenoma (APA), as compared with bilaterally simultaneous AVS. Methods results: In 138 consecutive patients who underwent subtyping primary...
Purpose: Aldosterone-producing adenoma (APA) is the main curable cause of endocrine hypertension primary aldosteronism (PA) and it in up to 66% all cases investigated with adrenal vein sampling (AVS). Mutations KCNJ5 potassium channel involve 70% APA most florid PA phenotypes. The recent finding that macrolide antibiotics specifically inhibit vitro altered function mutated channels has opened new horizons for diagnosis treatment mutations can allow identification target patients harbouring a...
Coronavirus disease 2019 (COVID-19) has rapidly become a global pandemic with lung representing the main cause of morbidity and mortality. Conventional chest-X ray (CXR) ultrasound (US) are valuable instruments to assess extent involvement. We investigated relationship between CXR scores on admission level medical care required in patients COVID-19. Further, we assessed CXR-US correlation explore role monitoring course COVID-19 pneumonia. Clinical features were obtained at correlated...
Many of the patients with primary aldosteronism (PA) are denied curative adrenalectomy because limited availability or failure adrenal vein sampling. It has been suggested that sampling can be omitted in young a unilateral nodule, who show florid biochemical PA phenotype. As this suggestion was based on very low quality evidence, we tested applicability and accuracy imaging, performed by computed tomography and/or magnetic resonance, for identification PA, as determined clinical cure after...
Success of adrenal vein sampling (AVS) is verified by the selectivity index (SI), i.e., a step-up cortisol levels between and infrarenal inferior vena cava samples, beyond given cut-off. We tested hypothesis that androstenedione, metanephrine, normetanephrine, which have higher gradients than cortisol, could increase rate AVS studies judged to be bilaterally successful usable for clinical decision making. prospectively compared within-patient, head-to-head, androstenedione (SIA),...
Background and Aims: HCC can increase the risk of nonneoplastic PVT in cirrhosis. However, natural history its prognostic role patients are unknown. Approach Results: Consecutive with cirrhosis undergoing laparoscopic ablation were retrospectively evaluated followed up to 36 months. characteristics evolution reviewed. was categorized according lumen occupancy (≤50%, >50% <100%, = 100%) extension other veins. The thrombosis considered at 1 year from diagnosis. Variables associated...
High-Resolution Computed Tomography (HRCT) plays a central role in diagnosing Idiopathic Pulmonary Fibrosis (IPF) while its monitoring disease progression is not clearly defined. Given the variable clinical course of disease, we evaluated whether HRCT abnormalities predict behavior and correlate with functional decline untreated IPF patients. Forty-nine patients (with HRCT1) were functionally categorized as rapid or slow progressors. Twenty-one had second HRCT2. Thirteen underwent lung...
As metoclopramide stimulates aldosterone secretion, we tested its usefulness in the assessment of lateralization primary aldosteronism by adrenal vein sampling (AVS).Prospective within-patient study consecutive patients undergoing AVS for subtyping.We compared diagnostic accuracy baseline and postmetoclopramide index relative (to cortisol) secretion indices (RASI) each gland with aldosterone-producing adenoma (APA) determined four corners criteria as reference diagnosis.We recruited 93 (mean...
Clinical evidence has emphasized the importance of coronary plaques’ characteristics, rather than lumen stenosis, for outcome cardiovascular events. Coronary computed tomographic angiography (CCTA) a well-established role as non-invasive tool assessing plaques. The aim this study was to compare clinical characteristics and CCTA-derived information stable patients with non-severe plaques in predicting major adverse cardiac events (MACEs) during follow-up. We retrospectively selected 371 (64%...
Although the primary cause of death in COVID-19 infection is respiratory failure, there evidence that cardiac manifestations may contribute to overall mortality and can even be death. More importantly, it recognized associated with a high incidence thrombotic complications.Evaluate if coronary artery calcium (CAC) score was useful predict in-hospital (in-H) patients COVID-19. Secondary end-points were needed for mechanical ventilation intensive care unit admission.Two-hundred eighty-four...
There is a lack of consensus on the optimal management fundal gastric varices (GVs) in patients with cirrhosis due to varied anatomy and hemodynamics. In this study, we evaluate safety efficacy trans-splenic anterograde coil-assisted transvenous occlusion (TACATO) for preventing recurrent bleeding GVs associated gastrorenal shunt (GRS). 4-year GRS-associated GV bleeding, without prior esophageal variceal ascites, or portal vein thrombosis, were eligible TACATO. Trans-splenic access was...