- Bone health and treatments
- Bone and Joint Diseases
- Cancer Diagnosis and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Osteomyelitis and Bone Disorders Research
- Dental Implant Techniques and Outcomes
- Facial Trauma and Fracture Management
- Reconstructive Facial Surgery Techniques
- Cleft Lip and Palate Research
- Oral and Maxillofacial Pathology
- Bone Tumor Diagnosis and Treatments
- Bone fractures and treatments
- Periodontal Regeneration and Treatments
- Medical and Biological Sciences
- Head and Neck Surgical Oncology
- Craniofacial Disorders and Treatments
- Oral health in cancer treatment
- Orthopedic Surgery and Rehabilitation
- Tracheal and airway disorders
- Orthopedic Infections and Treatments
- Radiopharmaceutical Chemistry and Applications
- Anatomy and Medical Technology
- Oral Health Pathology and Treatment
- Oral and gingival health research
- Cerebrovascular and Carotid Artery Diseases
University of Padua
2014-2024
University of Palermo
2020
University of Verona
2006-2016
University of Tennessee Health Science Center
2016
Università Campus Bio-Medico
2016
Azienda Ospedaliera Universitaria Integrata Verona
2011-2014
University Hospital Foundation
2014
Research Institute of Radiology
2006
University of Modena and Reggio Emilia
2000-2006
St Vincent's Hospital
2005
The Medication-Related Osteonecrosis of Jaws (MRONJ) diagnosis process and its prevention play a role great rising importance, not only on the Quality Life (QoL) patients, but also decision-making by majority dentists oral surgeons involved in MRONJ (primary secondary). present paper reports update conclusions from Consensus Conference—held at Symposium Italian Society Oral Pathology Medicine (SIPMO) (20 October 2018, Ancona, Italy)—after newest recommendations (2020) were published two...
Mesenchymal stem cells (MSCs) represent a promising therapeutic approach in nerve tissue engineering. To date, the local implantation of MSC injured nerves has been only route administration used. In case multiple sites injury, systemic capable reaching damaged would be advisable. this regard, we found that an intravenous adipose-derived (ASC) 1 week after sciatic crush murine model acute axonal damage, significantly accelerated functional recovery. Sciatic from ASC-treated mice showed...
MRONJ is a potentially serious complication of anti-resorptive (AR) treatment in patients with skeletal metastases due to various cancers as well osteoporosis (Campisi et al., 2014). may also develop anti-resorptive-naive individuals exposed variety anti-angiogenic agents (Mohamed, Nielsen, & Schiodt, 2018; Nicolatou-Galitis, Kouri, 2019; Pimolbutr, Porter, Fedele, 2018). lead reduced quality life jaw bone infections, chronic pain, tooth loss, impaired function, and disfigurement. Since the...
Management of osteonecrosis the jaw associated with antiresorptive agents is challenging, and outcomes are unpredictable. The severity disease main guide to management, can help predict prognosis. Most available staging systems for osteonecrosis, including widely-used American Association Oral Maxillofacial Surgeons (AAOMS) system, classify on basis clinical radiographic findings. However, inspection radiography limited in their ability identify extent necrotic bone compared computed...
Recent data suggest that the traditional definition of bisphosphonate-associated osteonecrosis jaw (ONJ) may exclude patients who present with non-exposed variant condition. To test hypothesis a proportion ONJ remain undiagnosed because their symptoms do not conform to case definition, we did secondary analysis from MISSION (Multicentre study on phenotype, and classification jaws associated bisphosphonates), cross-sectional large population were recruited in 13 European centres. Patients...
Objectives Osteonecrosis of the jaw ( ONJ ) is a potentially severe adverse effect bisphosphonates BP ). Although risk increases with increasing duration treatment, there are currently no reliable estimates time to onset TTO The objective this study was estimate and associated factors in ‐treated patients. Subjects Methods Retrospective analysis data from 22 secondary care centres seven countries relevant 349 patients who developed ‐related between 2004 2012. Results median (95% CI 6.0 years...
Introduction . The management of bisphosphonate-related osteonecrosis the jaw (BRONJ), with no evidence-based guidelines, remains controversial. We aimed to evaluate efficiency a conservative surgical treatment combining Er,Cr:YSGG laser and platelet-rich plasma (PRP) for BRONJ in cancer patients. Methods performed longitudinal cohort study. Inclusion criteria were (1) age ≥ 18 years; (2) diagnosis; (3) NBP because underlying cancer. Results consecutively recruited ten patients diagnosed...
Abstract Background Cancer treatment-induced bone loss (CTIBL) is the most common adverse event experienced by patients affected breast cancer (BC) patients, without metastases. Bone modifying agents (BMAs) therapy prescribed for prevention of CTIBL, but it exposes to risk MRONJ. Methods This multicentre hospital-based retrospective study included consecutive non-metastatic BC MRONJ related exposure low-dose BMAs CTIBL prevention. Patients’ data were retrospectively collected from clinical...
In in vivo tissue engineering, many implanted cells die because of hypoxic conditions immediately postimplantation. The aim this study was to determine whether delayed myoblast implantation, at day 4 or 7, improves survival compared with implantation 0 an arterio-venous loop (AB loop) chamber model. adult inbred Sprague-Dawley rats, AB inserted into a plastic (day 0). Group I, 0, two million DiI-labeled (neonatal inbred) myoblasts were around the loop. Groups II and III, created novel cell...
Objective Osteonecrosis of the jaw (ONJ) is a potentially severe adverse effect various medications (bisphosphonates, anti‐resorptive, and anti‐angiogenic drugs). ONJ pathogenesis still unclear although some risk factors have been recognized. Of these, rheumatoid arthritis (RA) has hypothesized as potential factor for developing ONJ. This observational study will describe multicenter case series patients affected with RA ONJ, it attempt to evaluate association between features...